Synthesis and evaluation of curcumin-related compounds for anticancer activity

2012 ◽  
Vol 53 ◽  
pp. 235-245 ◽  
Author(s):  
Xingchuan Wei ◽  
Zhi-Yun Du ◽  
Xi Zheng ◽  
Xiao-Xing Cui ◽  
Allan H. Conney ◽  
...  
2005 ◽  
Vol 13 (4) ◽  
pp. 1285-1291 ◽  
Author(s):  
Jingli Wang ◽  
Linxiang Zhao ◽  
Rui Wang ◽  
Min Lu ◽  
Duo Chen ◽  
...  

2002 ◽  
Vol 67 (10) ◽  
pp. 3290-3300 ◽  
Author(s):  
Tomohisa Moriguchi ◽  
Norio Asai ◽  
Kazuhisa Okada ◽  
Kohji Seio ◽  
Takuma Sasaki ◽  
...  

1987 ◽  
Vol 76 (6) ◽  
pp. 481-484 ◽  
Author(s):  
Philip W. Crawford ◽  
William O. Foye ◽  
Michael D. Ryan ◽  
Peter Kovacic

2004 ◽  
Vol 57 (11) ◽  
pp. 1091 ◽  
Author(s):  
Christopher J. Byrne ◽  
Mathew A. Cooper ◽  
Prudence A. Cowled ◽  
Robert A. W. Johnstone ◽  
Lorraine Mackenzie ◽  
...  

The synthesis of diporphyrins and analogous compounds related to those present in the oligomeric fraction (Photofrin II) obtained from hematoporphyrin derivative (HPD) is described. The photodynamic activity of these compounds, in vivo, varies from inactive to as active as Photofrin II. Factors that are important in determining this anticancer activity of the synthetic compounds are the presence of hydrophobic side chains, as well as the propionic acid side chains of the hematoporphyrin derived materials, and the nature of the linking group between the porphyrins.


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