scholarly journals ESTS guidelines for intraoperative lymph node staging in non-small cell lung cancer☆

2006 ◽  
Vol 30 (5) ◽  
pp. 787-792 ◽  
Author(s):  
D LARDINOIS ◽  
P DELEYN ◽  
P VANSCHIL ◽  
R PORTA ◽  
D WALLER ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lymph Node Staging ◽  
Small Cell Lung

Lymph node staging in non-small-cell lung cancer with FDG-PET scan: a prospective study on 690 lymph node stations from 68 patients.

1998 ◽  
Vol 16 (6) ◽  
pp. 2142-2149 ◽  
Author(s):  
J F Vansteenkiste ◽  
S G Stroobants ◽  
P R De Leyn ◽  
P J Dupont ◽  
J Bogaert ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Locally Advanced ◽  
Small Cell ◽  
Lymph Node Staging ◽  
Small Cell Lung ◽  
Visual Scale ◽  
Pet Ct

PURPOSE To compare the accuracy of computed tomography-(CT) scan and the radiolabeled glucose analog 18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) visually correlated with CT (PET + CT) in the locoregional lymph node (LN) staging of non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS Sixty-eight patients with potentially operable NSCLC underwent thoracic CT, PET, and invasive surgical staging (ISS). Imaging studies were read prospectively and blinded to the surgical and pathologic data. A five-point visual scale was used for the interpretation of LNs on PET. Afterwards, with knowledge of the pathology, the relationship between standardized uptake values (SUVs) and the presence of metastasis in LNs was explored in a receiver operating characteristic (ROC) analysis, and the likelihood ratios (LRs) for SUVs of LNs were determined. RESULTS ISS was available for 690 LN stations. CT correctly identified the nodal stage in 40 of 68 patients (59%), with understaging in 12 patients and overstaging in 16 patients. PET + CT was accurate in 59 patients (87%), with understaging in five patients and overstaging in four patients. In the detection of locally advanced disease (N2/N3), the sensitivity, specificity, and accuracy of CT were 75%, 63%, and 68%, respectively. For PET + CT, this was 93%, 95%, and 94% (P = .0004). In the ROC curve, the best SUV threshold to distinguish benign from malignant LNs was 4.40. The analysis with this SUV threshold was not superior to the use of a five-point visual scale. The LR of a SUV less than 3.5 in an LN was 0.152; for a SUV between 3.5 and 4.5, it was 3.157; and for a SUV greater than 4.5, it was 253.096. CONCLUSION PET + CT is significantly more accurate than CT alone in LN staging of NSCLC. A five-point visual scale is as accurate as the use of an SUV threshold for LNs in the distinction between benign and malignant nodes. The very high negative predictive value of mediastinal PET could reduce the need for mediastinal ISS in NSCLC substantially.

Mediastinal Lymph Node Staging With FDG-PET Scan in Patients With Potentially Operable Non-small Cell Lung Cancer

CHEST Journal ◽  
1997 ◽  
Vol 112 (6) ◽  
pp. 1480-1486 ◽  
Author(s):  
Johan F. Vansteenkiste ◽  
Sigrid G. Stroobants ◽  
Paul R. De Leyn ◽  
Patrick J. Dupont ◽  
Johny A. Verschakelen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Fdg Pet ◽  
Mediastinal Lymph Node ◽  
Small Cell ◽  
Lymph Node Staging ◽  
Small Cell Lung ◽  
Fdg Pet Scan

Quantitative Analysis and Effect of Attenuation Correction on Lymph Node Staging of Non-Small Cell Lung Cancer on SPECT and CT

2006 ◽  
Vol 186 (5) ◽  
pp. 1450-1457 ◽  
Author(s):  
Shinya Shiraishi ◽  
Seiji Tomiguchi ◽  
Daisuke Utsunomiya ◽  
Koichi Kawanaka ◽  
Kazuo Awai ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Quantitative Analysis ◽  
Small Cell Lung Cancer ◽  
Attenuation Correction ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lymph Node Staging ◽  
Small Cell Lung

Intrathoracic lymph node staging of potentially resectable non-small cell lung cancer - The role of PET-CT

2015 ◽  
Author(s):  
Raquel Rosa ◽  
Dionísio Maia ◽  
Ana Alves ◽  
Telma Lopes ◽  
Inês Gonçalves ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lymph Node Staging ◽  
Small Cell Lung ◽  
Pet Ct

scholarly journals Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-small-cell lung cancer

2014 ◽  
Vol 45 (5) ◽  
pp. 787-798 ◽  
Author(s):  
P. De Leyn ◽  
C. Dooms ◽  
J. Kuzdzal ◽  
D. Lardinois ◽  
B. Passlick ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Mediastinal Lymph Node ◽  
Small Cell ◽  
Lymph Node Staging ◽  
Small Cell Lung
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