scholarly journals Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance

2021 ◽  
Author(s):  
A. Laura Nijstad ◽  
Shelby Barnett ◽  
Arief Lalmohamed ◽  
Inez M. Bérénos ◽  
Elizabeth Parke ◽  
...  
Keyword(s):  
Clinical Pharmacology ◽  
Cytotoxic Drugs ◽  
Evidence Based ◽  
Neonates And Infants

Evidence-Based Morphine Dosing for Postoperative Neonates and Infants

2014 ◽  
Vol 53 (6) ◽  
pp. 553-563 ◽  
Author(s):  
Elke H. J. Krekels ◽  
Dick Tibboel ◽  
Saskia N. de Wildt ◽  
Ilse Ceelie ◽  
Albert Dahan ◽  
...  
Keyword(s):  
Evidence Based ◽  
Neonates And Infants

Role of Lactoferrin in Neonates and Infants: An Update

2018 ◽  
Vol 35 (06) ◽  
pp. 561-565 ◽  
Author(s):  
Alberto Dall'Agnola ◽  
Daniel Tomé ◽  
David Kaufman ◽  
Elena Tavella ◽  
Marta Pieretto ◽  
...  
Keyword(s):  
Quality Control ◽  
Young Children ◽  
Current Evidence ◽  
Evidence Based ◽  
Respiratory Pathogens ◽  
Bioactive Proteins ◽  
Different Types ◽  
Neonates And Infants ◽  
Infants And Young Children

AbstractLactoferrin is one of the most represented and important bioactive proteins in human and mammal milk. In humans, lactoferrin is responsible for several actions targeting anti-infective, immunological, and gastrointestinal domains in neonates, infants, and young children. Evidence-based data vouch for the ability of supplemented lactoferrin to prevent sepsis and necrotizing enterocolitis in preterm infants and to reduce the burden of morbidity related to gastrointestinal and respiratory pathogens in young children. However, several issues remain pending regarding answers and clarification related to quality control, correct intakes, optimal schedules and schemes of supplementations, interactions with probiotics, and different types of milk and formulas. This review summarizes the current evidence regarding lactoferrin and discusses the areas in need of further guidance prior to the adoption of strategies that include a routine use of lactoferrin in neonates and young children.

Best of Five MCQs for the MRCP Part 1 Volume 1

2017 ◽  
Keyword(s):  
Clinical Pharmacology ◽  
Royal College ◽  
Evidence Based ◽  
Medical Systems ◽  
High Quality ◽  
Alphabetical Order ◽  
Practice Questions

Best of Five MCQs for the MRCP Part 1 volumes 1-3 offers a comprehensive and trustworthy solution to anybody wishing to sit, pass, and excel at the Membership of the Royal College of Physicians Part 1 examination. Presented as a unique three-volume set, each volume features 375 high-quality practice questions on each of the medical systems and specialties in alphabetical order. Volume 1 features 375 Best of Five questions on clinical sciences, clinical haematology and oncology, cardiology, and clinical pharmacology, therapeutics and toxicology. All 375 questions contain questions written and reviewed by successful candidates and previous examiners, and are accompanied by detailed explanations and further reading, ensuring complete and successful revision for this challenging exam. Matched to the latest Royal College curricula in coverage and format, this dedicated resource provides readers with an accurate, authoritative and evidence-based companion to the MRCP Part 1.

scholarly journals Nursing Personnel in the Era of Personalized Healthcare in Clinical Practice

2020 ◽  
Vol 10 (3) ◽  
pp. 56
Author(s):  
Marios Spanakis ◽  
Athina E. Patelarou ◽  
Evridiki Patelarou
Keyword(s):  
Clinical Pharmacology ◽  
Clinical Practice ◽  
Healthcare System ◽  
Nursing Care ◽  
Healthcare Providers ◽  
Nursing Personnel ◽  
Evidence Based ◽  
Therapeutic Approaches ◽  
New Era ◽  
Healthcare It

Personalized, stratified, or precision medicine (PM) introduces a new era in healthcare that tries to identify and predict optimum treatment outcomes for a patient or a cohort. It also introduces new scientific terminologies regarding therapeutic approaches and the need of their adoption from healthcare providers. Till today, evidence-based practice (EBP) was focusing on population averages and their variances among cohorts for clinical values that are essential for optimizing healthcare outcome. It can be stated that EBP and PM are complementary approaches for a modern healthcare system. Healthcare providers through EBP often see the forest (population averages) but miss the trees (individual patients), whereas utilization of PM may not see the forest for the trees. Nursing personnel (NP) play an important role in modern healthcare since they are consulting, educating, and providing care to patients whose needs often needs to be individualized (personalized nursing care, PNC). Based on the clinical issues earlier addressed from clinical pharmacology, EBP, and now encompassed in PM, this review tries to describe the challenges that NP have to face in order to meet the requisites of the new era in healthcare. It presents the demands that should be met for upgrading the provided education and expertise of NP toward an updated role in a modern healthcare system.

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