scholarly journals Neratinib as extended adjuvant therapy in patients with copositive early breast cancer: German health technology assessment–driven analyses from the ExteNET study

2021 ◽  
Vol 150 ◽  
pp. 268-277
Author(s):  
Diana Lüftner ◽  
Hans Tesch ◽  
Marcus Schmidt ◽  
Andreas D. Hartkopf ◽  
Sarah Streicher ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adjuvant Therapy ◽  
Health Technology Assessment ◽  
Early Breast Cancer ◽  
Technology Assessment ◽  
Health Technology ◽  
German Health ◽  
Extended Adjuvant Therapy

Adoption of trastuzumab for breast cancer in four emerging countries in the use of health technology assessment: a case study

2016 ◽  
Vol 5 (4) ◽  
pp. 365-373 ◽  
Author(s):  
Eva Martín-Ruiz ◽  
Jaime Espín Balbino ◽  
Alexandre Lemgruber ◽  
Araceli Caro-Martínez ◽  
Fernanda Lessa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Health Technology Assessment ◽  
Technology Assessment ◽  
Health Technology ◽  
Emerging Countries

OP181 Adapting Evidence To Produce A Health Technology Assessment Of Mammography Screening: An Example From The West Bank

2021 ◽  
Vol 37 (S1) ◽  
pp. 4-4
Author(s):  
Lieke Fleur Heupink ◽  
Mervett Isbeih ◽  
Sharif Qaddomi ◽  
Elizabeth Peacocke ◽  
Ingvil Sæterdal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Cancer Screening ◽  
Health Technology Assessment ◽  
Breast Cancer Screening ◽  
Technology Assessment ◽  
Mammography Screening ◽  
West Bank ◽  
Health Technology ◽  
The West

IntroductionHealth technology assessment (HTA) can play a key role in evidence-based decision-making. However, HTA requires resources that might be lacking in low-income settings. To test the feasibility of adapting existing evidence as part of the HTA process, this project evaluated the effectiveness and economic impact of breast cancer screening programs for women over 40 years in the West Bank, where mammography screening is provided for free in governmental clinics.MethodsWe conducted a search for systematic reviews, HTAs and guidelines in electronic databases. We included the most recent global systematic review and meta-analysis that fulfilled our inclusion criteria. The European Network for Health Technology Assessment (EUnetHTA) adaptation toolkit was used to guide adaptation and undertake a budget impact analysis of the economic impact of mammography screening. We build capacity by working as a team of HTA experts and first-time HTA researchers. The results were disseminated to raise awareness for HTA.ResultsThe European Commission Guidelines on Breast Cancer Screening were identified as most recent global systematic review with meta-analyses, out of 2,365 references. The adapted evidence may inform policies on screening in the West Bank. Our experience is that adaption requires extensive skills and resources, including finding, assessing, and adapting relevant evidence. The EUnetHTA toolkit is useful, but also adds to the workload. Furthermore, local stakeholder engagement is important in topic selection, to access information, and to contextualize global evidence to the local setting.ConclusionsThis study is currently ongoing, but preliminary findings show that producing an HTA by adapting existing evidence in resource-limited settings is feasible. There is a need for nuanced guidance on transferability of evidence from other settings. Future studies should investigate innovative methods to optimize the adaption process. Capacity building in adaptation is important to ensure the production of quality HTA products. Inclusion of local team members and stakeholders is important for future development of HTA in the region.

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