scholarly journals Timing of sentinel node biopsy independently predicts disease-free and overall survival in clinical stage I-II melanoma patients: A multicentre study of the Italian Melanoma Intergroup (IMI)

2020 ◽  
Vol 137 ◽  
pp. 30-39
Author(s):  
Mario Mandalà ◽  
Francesca Galli ◽  
Roberto Patuzzo ◽  
Andrea Maurichi ◽  
Simone Mocellin ◽  
...  
Keyword(s):  
Overall Survival ◽  
Multicentre Study ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Clinical Stage ◽  
Stage I ◽  
Node Biopsy ◽  
Melanoma Patients ◽  
Disease Free

Socioeconomic and demographic factors associated with use of sentinel node biopsy and adjuvant biologic response modifiers in melanoma

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 6027-6027 ◽  
Author(s):  
J. R. Lange ◽  
D. Chang ◽  
B. E. Palis ◽  
C. M. Balch
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Clinical Stage ◽  
Stage I ◽  
Cancer Management ◽  
Node Biopsy ◽  
Insurance Type ◽  
Regional Metastases ◽  
Biologic Response ◽  
Socioeconomic And Demographic Factors

6027 Background: Cancer management may be influenced by factors other than disease characteristics. Little is known about the association of demographic and socioeconomic factors with melanoma care. Methods: The National Cancer Data Base, a hospital-based registry, was queried on reported use of adjuvant biologic response modifiers (BRM) for patients with resected regional metastases and the use of sentinel node biopsy (SNBx) for patients with clinical stage I and II melanoma in patients ages 1–69 between 1994 and 2003. Independent variables were age, sex, race, severity of disease, income, insurance type, U. S. Census region and type of treating facility. Analysis was performed by forward stepwise logistic regression. Results: Between 1994 and 2003, 37.8% of 10,790 patients with resected node-positive melanoma received BRM. Between 1998 and 2002, 61,251 patients with clinical stage I and II melanoma had a SNBx in 13.2%, 46.2%, 55.9%, and 41.7% of those with T1, T2, T3, and T4 tumors, respectively. In multivariate analysis, geographic variance in use of BRM and SNBx was striking ( Table ). Insurance type (commercial vs. others) and facility type (teaching/research vs. others) were also significantly associated with these modalities. Use of BRM was also associated with age, number of positive nodes and earlier treatment year, but not with sex, income or race. Use of SNBx was also associated with T stage, later treatment year, age and income, but not with sex or race. Conclusions: BRM and SNBx use varied significantly with geographic region, insurance type, and type of treating facility; this may have implications for provider education and public policy. [Table: see text] No significant financial relationships to disclose.

scholarly journals Sentinel node biopsy in clinical stage I testicular cancer enables early detection of occult metastatic disease

2019 ◽  
Vol 124 (3) ◽  
pp. 424-430 ◽  
Author(s):  
Joost M. Blok ◽  
J. Martijn Kerst ◽  
Erik Vegt ◽  
Oscar R. Brouwer ◽  
Richard P. Meijer ◽  
...  
Keyword(s):  
Early Detection ◽  
Testicular Cancer ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Metastatic Disease ◽  
Clinical Stage ◽  
Stage I ◽  
Node Biopsy ◽  
Occult Metastatic Disease

Sentinel node biopsy in cutaneous melanoma patients with germline CDKN2A mutation

2019 ◽  
Vol 45 (2) ◽  
pp. e151
Author(s):  
N. Ipenburg ◽  
J. Van der Hage ◽  
N. Kukutsch ◽  
H. Helgadottir ◽  
O. Nieweg ◽  
...  
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Cutaneous Melanoma ◽  
Cdkn2a Mutation ◽  
Node Biopsy ◽  
Melanoma Patients

116. Hybrid radio- and fluorescence guided sentinel node biopsy in melanoma patients

2012 ◽  
Vol 38 (9) ◽  
pp. 770
Author(s):  
O. Brouwer ◽  
B.E. Schaafsma ◽  
N.S. van den Berg ◽  
W.M.C. Klop ◽  
A.J.M. Balm ◽  
...  
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Node Biopsy ◽  
Melanoma Patients

Sentinel node biopsy in melanoma patients: The role of day surgery and local anaesthetic approach for quality-of-life and effective cost reduction.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19002-e19002
Author(s):  
Fabio Ricci ◽  
Erminio Saralli ◽  
Loreto Giovanni Capuano ◽  
Maurizio Dorkin ◽  
Mario Valleriani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Cost Reduction ◽  
Primary Melanoma ◽  
Day Surgery ◽  
Blue Dye ◽  
Node Biopsy ◽  
Melanoma Patients

e19002 Background: Sentinel node biopsy (SNB) is used in the management of melanoma patients without nodal metastases. Methods: From January 1, 1998 to December 31, 2011 we performed 182 SNBs at St. M. Goretti Hospital. Patients presented a primary melanoma, Breslow thickness equal to or higher than 1 mm, lower than 1 mm with regression and/or ulceration, and/or IV-V Clark level, and/or mitotic rate ≥ 1/mm2, according to the 7th edition melanoma staging system. All patients underwent pre-operative lymphoscintigraphy with intradermal injection of 50-70 MBq 99 mTc colloidal albumina particles, 50-80 nm size range, in 0.1-0.2 ml saline solution. We never used blue dye. All patients underwent surgical treatment 4-12 h. later. We performed SNB in day-surgery (DS) under local anaesthesia (LA). Surgery incision was 3-4 cm. This study was approved by an ethics committee, discussed with all patients and informed consent was obtained. Purpose of the study is to investigate the validity of this approach for quality of life and cost reduction. Results: 165 patients underwent SNB, 64 (38.7%) in the inguinal region, 83 (50.3%) in axilla, 1 (0.6%) in the popliteal region, 4 (2.4%) patients showed inguinal bilateral sentinel lymph-node (SLN), 6 (3.6%) axillary bilateral SLN, 4 (2.4%) axillary and 3 (1.8%) inguinal double SLN. The SLN identification rate was 100%. After surgery we distributed a questionnaire to the patients about the acceptability of this approach. In 32 patients SLN was positive. In these patients we performed radical lymphoadenectomy, 12 (37.5%) inguinal and 20 (62.5%) axillary. Conclusions: The results achieved are extremely accurate. This procedure is safe, well accepted by patients (98%), reported better quality of life. The oncological results are absolutely reliable. As regards hospital logistics, operations in DS and LA can be easily managed, leading to a significant cost reduction, 42.15% less expensive than the same operation performed under general anaesthesia.

Prognostic importance of lymph node tumor burden in melanoma patients staged by sentinel node biopsy

2002 ◽  
Vol 9 (10) ◽  
pp. 975-981 ◽  
Author(s):  
Jaime M. Ranieri ◽  
Jeffrey D. Wagner ◽  
Rafael Azuaje ◽  
D. Davidson ◽  
Stacie Wenck ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Tumor Burden ◽  
Node Biopsy ◽  
Prognostic Importance ◽  
Melanoma Patients
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