Hereditary gastric cancer

2018 ◽  
Vol 92 ◽  
pp. S4
Author(s):  
F. Carneiro
Keyword(s):  
Gastric Cancer ◽  
Hereditary Gastric Cancer

Hereditary Gastric Cancer Syndromes

2015 ◽  
Vol 24 (4) ◽  
pp. 765-777 ◽  
Author(s):  
Hugh Colvin ◽  
Ken Yamamoto ◽  
Noriko Wada ◽  
Masaki Mori
Keyword(s):  
Gastric Cancer ◽  
Hereditary Gastric Cancer ◽  
Cancer Syndromes

scholarly journals Family’s History Based on the CDH1 Germline Variant (c.360delG) and a Suspected Hereditary Gastric Cancer Form

2020 ◽  
Vol 21 (14) ◽  
pp. 4904
Author(s):  
Laura Caggiari ◽  
Mara Fornasarig ◽  
Mariangela De Zorzi ◽  
Renato Cannizzaro ◽  
Agostino Steffan ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Susceptibility ◽  
Stop Codon ◽  
Case Reports ◽  
Premature Stop Codon ◽  
Diffuse Gastric Cancer ◽  
Cancer Syndrome ◽  
The Family ◽  
Hereditary Gastric Cancer ◽  
E Cadherin

Hereditary diffuse gastric cancer (HDGC) is a cancer susceptibility syndrome caused by germline pathogenic variant in CDH1, the gene encoding E-cadherin. The germline loss-of-function variants are the only proven cause of the cancer syndrome HDGC, occurring in approximately 10–18% of cases and representing a helpful tool in genetic counseling. The current case reports the family history based on a CDH1 gene variant, c.360delG, p.His121Thr in a suspected family for hereditary gastric cancer form. This frameshift deletion generates a premature stop codon at the amino acid 214, which leads to a truncated E-cadherin protein detecting it as a deleterious variant. The present study expands the mutational spectra of the family with the CDH1 variant. Our results highlight the clinical impact of the reported CDH1 variant running in gastric cancer families.

Hereditary gastric cancer: what’s new? Update 2013–2018

2019 ◽  
Vol 18 (3) ◽  
pp. 363-367 ◽  
Author(s):  
Rachel S. van der Post ◽  
Carla Oliveira ◽  
Parry Guilford ◽  
Fátima Carneiro
Keyword(s):  
Gastric Cancer ◽  
Hereditary Gastric Cancer

Hereditary gastric cancer: Clinicopathologic characteristics in a young hispanic patient population

2003 ◽  
Vol 124 (4) ◽  
pp. A795-A796
Author(s):  
Heriberto Medina-Franco ◽  
Antonio Ramos-De la medina ◽  
Noel Salgado ◽  
Roberto Cisneros ◽  
Carlos Hinojosa
Keyword(s):  
Gastric Cancer ◽  
Patient Population ◽  
Clinicopathologic Characteristics ◽  
Hispanic Patient ◽  
Hereditary Gastric Cancer

scholarly journals E-cadherinis not frequently mutated in hereditary gastric cancer

2001 ◽  
Vol 38 (1) ◽  
pp. 49-52 ◽  
Author(s):  
E. AVIZIENYTE ◽  
V. LAUNONEN ◽  
R. SALOVAARA ◽  
T. KIVILUOTO ◽  
L. A. AALTONEN
Keyword(s):  
Gastric Cancer ◽  
Hereditary Gastric Cancer

Hereditary Gastric Cancer

2001 ◽  
Vol 1 (4) ◽  
pp. 194
Author(s):  
Han Kwang Yang ◽  
Yoon Ho Kim ◽  
Jae Gahb Park
Keyword(s):  
Gastric Cancer ◽  
Hereditary Gastric Cancer
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