scholarly journals Long-term risk of renal and urinary tract diseases in childhood cancer survivors: A population-based cohort study

2016 ◽  
Vol 64 ◽  
pp. 52-61 ◽  
Author(s):  
Trine Gade Bonnesen ◽  
Jeanette F. Winther ◽  
Peter H. Asdahl ◽  
Sofie de Fine Licht ◽  
Thorgerdur Gudmundsdottir ◽  
...  
Keyword(s):  
Cohort Study ◽  
Urinary Tract ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Population Based

scholarly journals Long-term inpatient disease burden in the Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study: A cohort study of 21,297 childhood cancer survivors

PLoS Medicine ◽  
2017 ◽  
Vol 14 (5) ◽  
pp. e1002296 ◽  
Author(s):  
Sofie de Fine Licht ◽  
Kathrine Rugbjerg ◽  
Thorgerdur Gudmundsdottir ◽  
Trine G. Bonnesen ◽  
Peter Haubjerg Asdahl ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Disease Burden ◽  
Adult Life ◽  
Childhood Cancer Survivors

Increased risk of antidepressant use in childhood cancer survivors: A Danish population-based cohort study

2015 ◽  
Vol 51 (5) ◽  
pp. 675-684 ◽  
Author(s):  
Lasse Wegener Lund ◽  
J.F. Winther ◽  
L. Cederkvist ◽  
K.K. Andersen ◽  
S.O. Dalton ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Population Based ◽  
Danish Population ◽  
Increased Risk ◽  
Antidepressant Use

Long-Term Incidence and Predictors of Significant Hearing Loss Requiring Hearing Assistive Devices Among Childhood Cancer Survivors: A Population-Based Study

2020 ◽  
Vol 38 (23) ◽  
pp. 2639-2646
Author(s):  
Jason A. Beyea ◽  
Cindy Lau ◽  
Bonnie Cooke ◽  
Stephen Hall ◽  
Paul C. Nathan ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Population Based ◽  
Assistive Devices ◽  
High Risk Populations ◽  
Multivariable Analyses ◽  
Treatment Predictors

PURPOSE Hearing loss is a significant late effect among childhood cancer survivors. Recent guidelines note insufficient evidence to quantify its natural history or risk associated with specific exposures. We examined the long-term incidence and predictors of hearing loss requiring hearing amplification devices (HADs) using population-based health care data. METHODS In Ontario, Canada, HAD costs are subsidized by the Assistive Devices Program (ADP). Ontario children < 18 years of age at cancer diagnosis between 1987 and 2016 were identified and linked to ADP claims. Cumulative HAD incidence was compared between cases and matched controls. Patient, disease, and treatment predictors of HAD were examined. RESULTS We identified 11,842 cases and 59,210 controls. Cases were at higher risk for HAD (hazard ratio [HR], 12.8; 95% CI, 9.8 to 16.7; P < .001). The cumulative incidence of HAD among survivors was 2.1% (95% CI, 1.7% to 2.5%) at 20 years and 6.4% (95% CI, 2.8% to 12.1%) at 30 years post-diagnosis. The 30-year incidence was highest in neuroblastoma (10.7%; 95% CI, 3.8% to 21.7%) and hepatoblastoma (16.2%; 95% CI, 8.6% to 26.0%) survivors. Predictors of HAD in multivariable analyses included age 0-4 years at diagnosis ( v 5-9 years; HR, 2.2; 95% CI, 1.4-3.3; P < .001). Relative to no cisplatin exposure, patients receiving < 200 mg/m2 were not at greater risk, unlike those receiving higher cumulative doses. Relative to no cranial or facial radiation, those who had received ≤ 32.00 Gy were at no higher risk, unlike those who had received > 32.00 Gy. Carboplatin exposure was not associated with HAD. CONCLUSION Childhood cancer survivors are at elevated risk for requiring HAD, which continues to increase between 20 and 30 years after diagnosis. Thresholds of cisplatin and radiation exposure exist, above which risk substantially increases. Prolonged monitoring and trials of otoprotective agents are warranted in high-risk populations.

scholarly journals Assessment of potential bias from non-participation in a dynamic clinical cohort of long-term childhood cancer survivors: Results from the St. Jude lifetime cohort study

2012 ◽  
Vol 60 (5) ◽  
pp. 856-864 ◽  
Author(s):  
Rohit P. Ojha ◽  
S. Cristina Oancea ◽  
Kirsten K. Ness ◽  
Jennifer Q. Lanctot ◽  
D. Kumar Srivastava ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Potential Bias ◽  
Clinical Cohort

scholarly journals A detailed insight in the high risks of hospitalizations in long-term childhood cancer survivors—A Dutch LATER linkage study

PLoS ONE ◽  
2020 ◽  
Vol 15 (5) ◽  
pp. e0232708
Author(s):  
Nina Streefkerk ◽  
Wim J. E. Tissing ◽  
Joke C. Korevaar ◽  
Eline van Dulmen-den Broeder ◽  
Dorine Bresters ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Linkage Study

scholarly journals Determining transition readiness in Swiss childhood cancer survivors – a feasibility study

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Maria Otth ◽  
Patrick Wechsler ◽  
Sibylle Denzler ◽  
Henrik Koehler ◽  
Katrin Scheinemann
Keyword(s):  
Health Care ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Self Management ◽  
Transition Readiness ◽  
Long Term Follow Up ◽  
Time Point

Abstract Background The successful transition of childhood cancer survivors (CCSs) from pediatric to adult long-term follow-up care is a critical phase, and determining the right time point can be challenging. We assessed the feasibility of the use of existing transition readiness tools in the context of the Swiss health care system, assessed partly transition readiness in Swiss CCSs, and compared our findings with Canadian CCSs for which these tools were originally developed. Methods We officially translated the Cancer Worry Scale (CWS) and Self-Management Skill Scale (SMSS) into German and integrated them into this cross-sectional study. We included CCSs attending the long-term follow-up (LTFU) clinic in the Division of Oncology-Hematology, Department of Pediatrics, Kantonsspital Aarau. We used descriptive statistics to describe transition readiness. Results We randomly recruited 50 CCSs aged ≥18 years at participation. The CCSs had a median CWS score of 62 (interquartile range 55–71), indicating a moderate level of cancer-related worry. Despite high self-management skills, some answers showed a dependency of CCSs on their parents. Our experience shows that the CWS and SMSS are easy for Swiss CCSs to use, understand, and complete. The interpretation of the results must take differences in health care systems between countries into account. Conclusions The translated CWS and SMSS are appropriate additional measures to assess transition readiness in CCSs. These scales can be used longitudinally to find the individual time point for transition and the completion by CCSs enables the health care team to individualize the transition process and to support the CCSs according to their individual needs.

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