Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer – A pooled analysis of PORTEC 1 and 2 trials

2015 ◽  
Vol 51 (13) ◽  
pp. 1742-1750 ◽  
Author(s):  
Tjalling Bosse ◽  
Elke E.M. Peters ◽  
Carien L. Creutzberg ◽  
Ina M. Jürgenliemk-Schulz ◽  
Jan J. Jobsen ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Risk Factor ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Pooled Analysis ◽  
Vascular Space ◽  
Risk Factor For Recurrence ◽  
Vascular Space Invasion

Rate of osseous metastases as identified by PET/CT in endometrial cancer: serous histology is a significant risk factor

2020 ◽  
Vol 156 (3) ◽  
pp. e30
Author(s):  
L. Hong ◽  
L. Cristiano ◽  
B. Cristiano ◽  
J. Unternaehrer ◽  
Y. Ioffe
Keyword(s):  
Endometrial Cancer ◽  
Risk Factor ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Osseous Metastases ◽  
Pet Ct

scholarly journals Spread through air spaces is an independent predictor of recurrence in stage III (N2) lung adenocarcinoma

2019 ◽  
Vol 29 (3) ◽  
pp. 442-448 ◽  
Author(s):  
Yuriko Terada ◽  
Tsuyoshi Takahashi ◽  
Shigeki Morita ◽  
Kosuke Kashiwabara ◽  
Kazuhiro Nagayama ◽  
...  
Keyword(s):  
Risk Factor ◽  
Lung Adenocarcinoma ◽  
Early Stage ◽  
Free Probability ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Stage Iii ◽  
Pattern Of Invasion ◽  
The Impact ◽  
Risk Factor For Recurrence

Abstract OBJECTIVES Spread through air space (STAS) is recognized as a pattern of invasion in lung adenocarcinoma and has been reported to be a predictor of recurrence and survival in patients with early-stage lung adenocarcinoma. However, this parameter has not been studied well in stage III (N2) lung adenocarcinoma. In this study, we evaluated the association between STAS invasion patterns and recurrence and survival in stage III (N2) lung adenocarcinoma. METHODS We retrospectively reviewed data from 76 patients at University of Tokyo with stage III (N2) lung adenocarcinoma who underwent surgery from August 1998 to December 2013. Statistical analysis was performed to determine the impact of STAS invasion clinicopathological features and clarify the relationship between this pattern of invasion and survival. RESULTS Tumour STAS was observed in 46 of 76 patients (60.5%) and was significantly associated with the presence of lymphatic invasion (P < 0.001), papillary components (P < 0.001) and micropapillary components (P < 0.001). STAS was also significantly associated with recurrence (5-year recurrence-free probability: 19.0% vs 46.1%, P < 0.05). Univariate analyses showed that STAS was a significant risk factor for recurrence (hazard ratio 1.94, 95% confidence interval 1.07–3.51; P = 0.029). CONCLUSIONS The presence of STAS invasion pattern is a significant risk factor for recurrence in stage III (N2) lung adenocarcinoma.

scholarly journals Inferior Surface Leukoplakia of Vocal Folds: Risk of Recurrence: A Preliminary Study

2021 ◽  
pp. 014556132198943
Author(s):  
Hisashi Hasegawa ◽  
Hiroumi Matsuzaki ◽  
Kiyoshi Makiyama ◽  
Takeshi Oshima
Keyword(s):  
Risk Factor ◽  
Vocal Fold ◽  
Significant Risk ◽  
Vocal Folds ◽  
Significant Risk Factor ◽  
Clinicopathological Characteristics ◽  
Inferior Surface ◽  
Preliminary Study ◽  
Risk Factor For Recurrence ◽  
Vocal Fold Leukoplakia

Objectives: This study aimed to identify vocal fold leukoplakia (VFL) lesions on the inferior surface as a risk factor for recurrence. Methods: This was a retrospective study with data collected from 2001 to 2018. The study comprised 37 patients with VFL, divided into the nonrecurrent and recurrent groups. We examined the clinicopathological characteristics and the surgical procedures performed in each patient. Results: Among the 37 patients, 15 (40.5%) had residual (3) or recurrent (12) VFL. Of those patients with and without recurrence, 8 of 12 (66.7%) and 6 of 22 (27.3%), respectively, had inferior surface lesions of the vocal fold at the initial operation ( P = .036). Recurrences were significantly higher in patients with inferior surface lesions. Other evaluated factors did not show significance for recurrence. Conclusion: The presence of VFL lesions on the inferior surface is a significant risk factor for recurrence.

Insulin resistance: A significant risk factor of endometrial cancer

2012 ◽  
Vol 125 (3) ◽  
pp. 751-757 ◽  
Author(s):  
Nan Mu ◽  
Yuanxi Zhu ◽  
Yingmei Wang ◽  
Huiying Zhang ◽  
Fengxia Xue
Keyword(s):  
Insulin Resistance ◽  
Endometrial Cancer ◽  
Risk Factor ◽  
Significant Risk ◽  
Significant Risk Factor
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