Metformin significantly reduces incident prostate cancer risk in Taiwanese men with type 2 diabetes mellitus

2014 ◽  
Vol 50 (16) ◽  
pp. 2831-2837 ◽  
Author(s):  
Chin-Hsiao Tseng
Keyword(s):  
Prostate Cancer ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cancer Risk ◽  
Prostate Cancer Risk ◽  
Taiwanese Men

Prostate cancer genetic propensity risk score may modify the association between this tumour and type 2 diabetes mellitus (MCC-Spain study)

2021 ◽  
Author(s):  
Rocío Barrios-Rodríguez ◽  
Esther García-Esquinas ◽  
Beatriz Pérez-Gómez ◽  
Gemma Castaño-Vinyals ◽  
Javier Llorca ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Risk Score ◽  
Cancer Genetic

scholarly journals The association between type 2 diabetes mellitus and bladder cancer risk among postmenopausal women

2020 ◽  
Vol 31 (5) ◽  
pp. 503-510
Author(s):  
Yueyao Li ◽  
Michael S. Hendryx ◽  
Pengcheng Xun ◽  
Ka He ◽  
Aladdin H. Shadyab ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Bladder Cancer ◽  
Type 2 Diabetes Mellitus ◽  
Cancer Risk ◽  
Postmenopausal Women ◽  
Bladder Cancer Risk

scholarly journals Men with type 2 diabetes mellitus have a lower detection rate of prostate cancer

2020 ◽  
Vol 27 (9) ◽  
pp. 817-820
Author(s):  
Mohammad‐Ali Haghsheno ◽  
Jan Hammarsten ◽  
Ralph Peeker ◽  
Carl Johan Behre ◽  
Dan Mellström ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Detection Rate ◽  
Lower Detection

Gender-specific effects of oral hypoglycaemic agents on cancer risk in type 2 diabetes mellitus

2013 ◽  
Vol 16 (3) ◽  
pp. 276-283 ◽  
Author(s):  
G. E. C. Sun ◽  
B. J. Wells ◽  
K. Yip ◽  
R. Zimmerman ◽  
D. Raghavan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cancer Risk ◽  
Oral Hypoglycaemic Agents ◽  
Hypoglycaemic Agents ◽  
Specific Effects ◽  
Gender Specific

scholarly journals Exploring the Association Between Prostate Cancer Diagnosis per se and use of GnRH Agonists and Diabetes Control in Men with type 2 Diabetes Mellitus: A Nationwide, Population-Based Cohort Study

2021 ◽  
Author(s):  
E Lin ◽  
Hans Garmo ◽  
Mieke Hemelrijck ◽  
Jan Adolfsson ◽  
Pär Stattin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Population Based ◽  
Diabetes Control ◽  
Gnrh Agonists ◽  
Cancer Data

Abstract Background: Gonadotropin Releasing Hormones agonists (GnRH), which are first line treatment for metastatic prostate cancer (PCa), increase risk of type 2 diabetes mellitus (T2DM). This study aims to quantify the association of use of GnRH with diabetes control in PCa men with T2DM.Methods: Nationwide population-based cohort study in the Swedish National Diabetes Register and Prostate Cancer data Base Sweden 4.1, on the association between GnRH and diabetes control in T2DM men with PCa by comparing T2DM men with PCa vs. without PCa, as well as comparing T2DM men with PCa on or not on GnRH. The primary exposure was use of GnRH. Worsening diabetes control was the primary outcome, defined as: 1) increase of HbA1c to 58 mmol/mol or higher; 2) HbA1c increase by 10 mmol/mol or more; 3) Start of antidiabetic drugs or switch to insulin; 4) combine all definitions above. Cox proportional hazards regression was used to analyze the association. Results: There were 5,714 T2DM men with PCa of whom 692 were on GnRH and 28,445 PCa-free men with T2DM with similar baseline characteristics. Diabetes control was worse in men with GnRH vs. PCa-free men (HR: 1.24, 95% CI: 1.13-1.34) as well as compared with PCa men without GnRH (HR:1.58, 95% CI: 1.39-1.80). Conclusion: Use of GnRH in T2DM men with PCa was associated with worse glycemic control. The findings highlight the need to closely monitor diabetes control in men with T2DM and PCa starting GnRH agonists and to limit the duration of their use when possible.

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