Lymphovascular invasion as a prognostic factor in the upper urinary tract urothelial carcinoma: A systematic review and meta-analysis

2013 ◽  
Vol 49 (12) ◽  
pp. 2665-2680 ◽  
Author(s):  
Ja Hyeon Ku ◽  
Seok-Soo Byun ◽  
Hyeon Jeong ◽  
Cheol Kwak ◽  
Hyeon Hoe Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Urinary Tract ◽  
Prognostic Factor ◽  
Urothelial Carcinoma ◽  
Lymphovascular Invasion ◽  
Meta Analysis ◽  
Upper Urinary Tract ◽  
Urinary Tract Urothelial Carcinoma

Ki-67 as a Prognostic Marker in Upper Urinary Tract Urothelial Carcinoma: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 16 (4) ◽  
pp. e831-e841 ◽  
Author(s):  
Chihyun Ahn ◽  
Chang Wook Jeong ◽  
Cheol Kwak ◽  
Hyeon Hoe Kim ◽  
Hyung Suk Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Prognostic Marker ◽  
Meta Analysis ◽  
Upper Urinary Tract ◽  
Ki 67 ◽  
Urinary Tract Urothelial Carcinoma

The Role of p53 on Survival of Upper Urinary Tract Urothelial Carcinoma: A Systematic Review and Meta-Analysis

2013 ◽  
Vol 11 (3) ◽  
pp. 221-228 ◽  
Author(s):  
Ja Hyeon Ku ◽  
Seok-Soo Byun ◽  
Hyeon Jeong ◽  
Cheol Kwak ◽  
Hyeon Hoe Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Meta Analysis ◽  
Upper Urinary Tract ◽  
Urinary Tract Urothelial Carcinoma

scholarly journals Prognostic Value of Lymphovascular Invasion in Upper Urinary Tract Urothelial Carcinoma after Radical Nephroureterectomy: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-15 ◽  
Author(s):  
Wen Liu ◽  
Lijiang Sun ◽  
Fengju Guan ◽  
Fangming Wang ◽  
Guiming Zhang
Keyword(s):  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Publication Bias ◽  
Prognostic Value ◽  
Lymphovascular Invasion ◽  
Meta Analysis ◽  
Upper Urinary Tract ◽  
Cochrane Library ◽  
Radical Nephroureterectomy ◽  
Urinary Tract Urothelial Carcinoma

This study was performed to identify the prognostic impact of lymphovascular invasion (LVI) in patients with upper urinary tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU). A systematic search in PubMed, Embase, and the Cochrane Library was performed to identify relevant studies. The outcomes of interest, including progression-free survival (PFS), cancer-specific survival (CSS), and overall survival (OS), were extracted, and the pooled hazard ratios (HRs) and 95% confidence intervals (CIs) were used for effect size estimation. Subgroup, metaregression, and sensitivity analyses were performed to explore potential origins of heterogeneity. Publication bias was estimated by Egger’s linear regression and funnel plot. Our meta-analysis included a total of 27 studies involving 17,453 patients. The pooled HRs were statistically significant for PFS (HR=1.73, 95%CI=1.41–2.11), CSS (HR=1.87, 95%CI=1.54–2.27), and OS (HR=1.56, 95%CI=1.29–1.87), with high heterogeneity (I2=77.8%, 70.3%, and 59.2%, respectively). Four studies explored the prognostic value of LVI in patients with advanced tumor stages (T3–T4). The fixed effects model (I2=33.9%) showed that the pooled HR was 1.64 (95%CI=1.35–1.99) for CSS. Egger’s plots showed no significant publication bias (PFS: P=0.443, CSS: P=0.096, and OS: P=0.894). Our meta-analysis demonstrated that LVI is a poor prognostic factor for UTUC and is strongly associated with disease recurrence, cancer-specific mortality, and overall mortality.

Perioperative chemotherapy for urothelial carcinoma of the upper urinary tract: A systematic review and meta-analysis

2018 ◽  
Vol 128 ◽  
pp. 58-64 ◽  
Author(s):  
Richard W. Gregg ◽  
Francisco E. Vera-Badillo ◽  
Christopher M. Booth ◽  
Aamer Mahmud ◽  
Michael Brundage ◽  
...  
Keyword(s):  
Systematic Review ◽  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Meta Analysis ◽  
Upper Urinary Tract ◽  
Perioperative Chemotherapy
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