Cetuximab in the management of locoregionally advanced head and neck cancer: Expanding the treatment options?

2010 ◽  
Vol 46 (11) ◽  
pp. 1979-1989 ◽  
Author(s):  
Jean Bourhis ◽  
Jean-Louis Lefebvre ◽  
Jan B. Vermorken
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Treatment Options ◽  
Advanced Head

“CLINICALASSESSMENT OF TREATMENT RELATED TOXICITY AND RESPONSE BY CONCOMITANT CHEMORADIATION THERAPY IN LOCALLY ADVANCED HEAD AND NECK CARCINOMA”

2021 ◽  
pp. 79-81
Author(s):  
Swapan Kumar Mallick ◽  
Rinki Saha
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Treatment Options ◽  
Locally Advanced ◽  
Stage Iv ◽  
Head And Neck Carcinoma ◽  
Complete Response ◽  
Advanced Head

Introduction: Head and neck cancer is the commonest malignancy in India. Most of the cases present are at a locally advanced stage. Concurrent chemo radiotherapy is one of the treatment options in locally advanced Head & Neck Cancer patients. Materials & Methods: Locally advanced head and neck cancer patients attending the Out Patient Department of Radiotherapy from May 2018 to February 2020. Patients were treated with concurrent chemoradiation and followed for a minimum period of 9 months. Results: On analysing the pattern of response, it was noted that, in the chemoradiation complete response was seen in 20 patients (66.66%), partial response in 6 patients (20%), stable disease in 2 patients (6.66%) and progressive disease in 1 patient (3.33%). In our study, complete Response in case of Stage III was seen in 18 patients and other form of response was seen in 3 patients . In case of Stage IV A and IV B , Complete Response in 2 patients and other form of response was in 6 patients respectively. Haematological toxicities like neutropenia (3.3%), thrombocytopenia (0%) and anaemia (3.3%) were seen. Acute toxicities like oral mucositis and skin reaction were observed 10% in both the cases. Conclusions: The present study, Concomitant chemoradiotherapy improved overall survival and locoregional control. Preservation of function is a major endpoint of interest.

scholarly journals Salvage Neck Dissection after Chemoradiation in Head and Neck Cancer: Practice and Pitfalls

2012 ◽  
Vol 3 (1) ◽  
pp. 15-21
Author(s):  
Vedang Murthy ◽  
Sayan Kundu ◽  
Ashwini Budrukkar ◽  
Tejpal Gupta ◽  
Sarbani Ghosh Laskar ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Dissection ◽  
Neck Cancer ◽  
Future Development ◽  
Treatment Options ◽  
Locally Advanced ◽  
Advanced Head ◽  
Current State ◽  
Salvage Neck Dissection

ABSTRACT Locally advanced head and neck cancers are usually treated with concurrent chemoradiation. The residual nodes after chemoradiation in such patients are a common scenario, but the further investigation and treatment options in form of neck dissection are still not very clear. This review focuses on the current state of available evidence in literature for management of such patients and directs for the future development to fill the lacunae. How to cite this article Agarwal J, Kundu S, Krishnatry R Gupta T, Murthy V, Budrukkar A, Laskar SG. Salvage Neck Dissection after Chemoradiation in Head and Neck Cancer: Practice and Pitfalls. Int J Head and Neck Surg 2012;3(1): 15-21.

Acute haemorrhage in patients with advanced head and neck cancer: value of endovascular therapy as palliative treatment option

2005 ◽  
Vol 120 (2) ◽  
pp. 117-124 ◽  
Author(s):  
Andreas M Sesterhenn ◽  
Joanna Iwinska-Zelder ◽  
Carsten V Dalchow ◽  
Siegfried Bien ◽  
Jochen A Werner
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Endovascular Therapy ◽  
Treatment Options ◽  
Neurological Complication ◽  
Advanced Head ◽  
Emergency Procedure ◽  
Acute Bleeding ◽  
Acute Haemorrhage

Aims: Acute or subacute haemorrhage is one of the most frightening complications in patients suffering from advanced head and neck cancer. Few articles report experience with superselective endovascular therapy for this purpose. Is endovascular therapy underestimated in the field of palliative head and neck cancer therapy? This study set out to investigate this question.Patients and methods: A review was undertaken of the clinical courses of seven patients (six men, one woman) suffering from incurable, advanced head and neck cancer (four pharyngeal, two laryngeal, one neck) and treated with superselective endovascular strategies as an emergency procedure for acute bleeding.Results: All patients were successfully treated without evidence of neurological complication. Patients reached a median survival of 20 weeks (range eight–168 weeks). Following endovascular treatment all patients were discharged from the hospital within several days. Three patients survived almost free of symptoms for several weeks and were able to stay at home with their families until their death.Conclusion: We conclude that in the field of palliative care, superselective endovascular therapy deserves to be considered alongside standard treatment options for the management of acute haemorrhage from advanced head and neck cancer.

Nutritional status as a prognostic factor in advanced head and neck cancer

1998 ◽  
Vol 23 (4) ◽  
pp. 376-376
Author(s):  
Quak ◽  
Van Bokhorst ◽  
Klop ◽  
Van Leeuwen ◽  
Snow
Keyword(s):  
Head And Neck Cancer ◽  
Prognostic Factor ◽  
Nutritional Status ◽  
Head And Neck ◽  
Neck Cancer ◽  
Advanced Head

Three-Dimensional Exoscopic Temporal Bone Resections for Advanced Head and Neck Cancer

2020 ◽  
Author(s):  
Mallory J. Raymond ◽  
Roberto M. Soriano ◽  
Ryan Belcher ◽  
C. Arturo Solares
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Temporal Bone ◽  
Neck Cancer ◽  
Three Dimensional ◽  
Advanced Head
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