The role of glutathione-S-transferase polymorphisms in ovarian cancer survival

2007 ◽  
Vol 43 (2) ◽  
pp. 283-290 ◽  
Author(s):  
Christina M. Nagle ◽  
Georgia Chenevix-Trench ◽  
Amanda B. Spurdle ◽  
Penelope M. Webb
Keyword(s):  
Ovarian Cancer ◽  
Cancer Survival ◽  
Glutathione S Transferase ◽  
Ovarian Cancer Survival

Role of hypertension associated genes with ovarian cancer survival in the TCGA data.

2012 ◽  
Vol 125 ◽  
pp. S38
Author(s):  
S. Hensley Alford ◽  
J. Li ◽  
X. Yang ◽  
T. Buekers ◽  
A. Munkarah
Keyword(s):  
Ovarian Cancer ◽  
Cancer Survival ◽  
Ovarian Cancer Survival

scholarly journals On the Reproducibility of TCGA Ovarian Cancer MicroRNA Profiles

2013 ◽  
Author(s):  
Ying-Wooi Wan ◽  
Claire Mach ◽  
Genevera I. Allen ◽  
Matthew Anderson ◽  
Zhandong Liu
Keyword(s):  
Ovarian Cancer ◽  
Cancer Survival ◽  
Human Cancer ◽  
The Cancer Genome Atlas ◽  
Detection Algorithms ◽  
Level 3 ◽  
Cancer Genome Atlas ◽  
Ovarian Cancer Survival ◽  
Generation Sequencing

Dysregulated microRNA (miRNA) expression is a well-established feature of human cancer. However, the role of specific miRNAs in determining cancer outcomes remains unclear. Using Level 3 expression data from the Cancer Genome Atlas (TCGA), we identified 61 miRNAs that are associated with overall survival in 469 ovarian cancers profiled by microarray (p<0.01). We also identified 12 miRNAs that are associated with survival when miRNAs were profiled in the same specimens using Next Generation Sequencing (miRNA-Seq) (p<0.01). Surprisingly, only 1 miRNA transcript is associated with ovarian cancer survival in both datasets. Our analyses indicate that this discrepancy is due to the fact that miRNA levels reported by the two platforms correlate poorly, even after correcting for potential issues inherent to signal detection algorithms. Further investigation is warranted.

Vaginal hysterectomy with or without bilateral salpingo-oophorectomy may be an alternative treatment for endometrial cancer patients with medical co-morbidities precluding standard surgical procedures: a systematic review

2019 ◽  
Vol 29 (2) ◽  
pp. 299-304 ◽  
Author(s):  
Arnold-Jan Kruse ◽  
Henk G ter Brugge ◽  
Harm H de Haan ◽  
Hugo W Van Eyndhoven ◽  
Hans W Nijman
Keyword(s):  
Ovarian Cancer ◽  
Endometrial Cancer ◽  
Vaginal Hysterectomy ◽  
Cancer Survival ◽  
Survival Rates ◽  
Survival Outcomes ◽  
Ovarian Malignancy ◽  
Post Menopausal ◽  
Ovarian Cancer Survival ◽  
Overall Survival Rates

ObjectiveVaginal hysterectomy with bilateral salpingo-oophorectomy may be an alternative strategy for patients with low-risk endometrial cancer and medical co-morbidities precluding laparoscopic or abdominal procedures. The current study evaluates the prevalence of co-existent ovarian malignancy in patients with endometrial cancer and the influence of bilateral salpingo-oophorectomy on survival outcomes in these patients.MethodsMedline and EMBASE were searched for studies published between January 1, 2000 and November 20, 2017 that investigated (1) the prevalence of co-existing ovarian malignancy (either metastases or primary synchronous ovarian cancer in women with endometrial cancer, and (2) the influence of bilateral salpingo-oophorectomy on recurrence and/or survival rates.ResultsOf the pre-menopausal and post-menopausal patients (n=6059), 373 were identified with metastases and 106 were identified with primary synchronous ovarian cancer. Of the post-menopausal patients (n=6016), 362 were identified with metastases and 44 were identified with primary synchronous ovarian cancer. Survival outcomes did not differ for pre-menopausal patients with endometrial cancer with and without bilateral salpingo-oophorectomy (5-year overall survival rates were 89–94.5% and 86–97.8%, respectively).ConclusionBilateral salpingo-oophorectomy during vaginal hysterectomy seems to have a limited impact on disease outcome in patients with endometrial cancer. These results support the view that vaginal hysterectomy alone or with bilateral salpingo-oophorectomy may be an option for patients with endometrial cancer who are not ideal surgical candidates.

Ambient air pollution and ovarian cancer survival in California

2021 ◽  
Author(s):  
Carolina Villanueva ◽  
Jenny Chang ◽  
Argyrios Ziogas ◽  
Robert E. Bristow ◽  
Verónica M. Vieira
Keyword(s):  
Ovarian Cancer ◽  
Air Pollution ◽  
Cancer Survival ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Ovarian Cancer Survival

Usual Adult Body Mass Index Is Not Predictive of Ovarian Cancer Survival

2007 ◽  
Vol 16 (3) ◽  
pp. 626-628 ◽  
Author(s):  
Kirsten B. Moysich ◽  
Julie A. Baker ◽  
Ravi J. Menezes ◽  
Vijayvel Jayaprakash ◽  
Kerry J. Rodabaugh ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Body Mass Index ◽  
Body Mass ◽  
Cancer Survival ◽  
Adult Body Mass ◽  
Adult Body ◽  
Adult Body Mass Index ◽  
Ovarian Cancer Survival

Disparity of ovarian cancer survival between urban and rural settings

2021 ◽  
Vol 162 ◽  
pp. S137-S138
Author(s):  
Keely Ulmer ◽  
Nicholas Cardillo ◽  
Megan McDonald ◽  
David Bender ◽  
Michael Goodheart ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Survival ◽  
Rural Settings ◽  
Ovarian Cancer Survival

Impact of beta blockers on epithelial ovarian cancer survival

2012 ◽  
Vol 127 (2) ◽  
pp. 375-378 ◽  
Author(s):  
Elena S. Diaz ◽  
Beth Y. Karlan ◽  
Andrew J. Li
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Cancer Survival ◽  
Beta Blockers ◽  
Ovarian Cancer Survival
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