The role of mannose-binding lectin (MBL) in paediatric oncology patients with febrile neutropenia

2006 ◽  
Vol 42 (7) ◽  
pp. 909-916 ◽  
Author(s):  
F.N.J. Frakking ◽  
M.D. van de Wetering ◽  
N. Brouwer ◽  
K.M. Dolman ◽  
J. Geissler ◽  
...  
Keyword(s):  
Febrile Neutropenia ◽  
Paediatric Oncology ◽  
Mannose Binding Lectin ◽  
Oncology Patients ◽  
Mannose Binding ◽  
Binding Lectin

Mannose-binding lectin (MBL) and the risk for febrile neutropenia and infection in pediatric oncology patients with chemotherapy

2010 ◽  
Vol 57 (1) ◽  
pp. 89-96 ◽  
Author(s):  
F.N.J. Frakking ◽  
J. Israëls ◽  
L.C.M. Kremer ◽  
T.W. Kuijpers ◽  
H.N. Caron ◽  
...  
Keyword(s):  
Febrile Neutropenia ◽  
Pediatric Oncology ◽  
Mannose Binding Lectin ◽  
Oncology Patients ◽  
Mannose Binding ◽  
Binding Lectin

The role of mannose binding lectin on fever episodes in pediatric oncology patients

2015 ◽  
Vol 22 (1) ◽  
pp. 139-143 ◽  
Author(s):  
Ferenc Fekete ◽  
Balázs Fadgyas ◽  
Éva Papp ◽  
Ágnes Szilágyi ◽  
Zoltán Prohászka ◽  
...  
Keyword(s):  
Pediatric Oncology ◽  
Mannose Binding Lectin ◽  
Oncology Patients ◽  
Mannose Binding ◽  
Binding Lectin

scholarly journals Mannose-binding lectin (MBL) as prognostic factor in paediatric oncology patients

2011 ◽  
Vol 165 (1) ◽  
pp. 51-59 ◽  
Author(s):  
F. N. J. Frakking ◽  
N. Brouwer ◽  
K. M. Dolman ◽  
J. B. M. van Woensel ◽  
H. N. Caron ◽  
...  
Keyword(s):  
Prognostic Factor ◽  
Paediatric Oncology ◽  
Mannose Binding Lectin ◽  
Oncology Patients ◽  
Mannose Binding ◽  
Binding Lectin

Mannose-binding lectin genetics: from A to Z

2008 ◽  
Vol 36 (6) ◽  
pp. 1461-1466 ◽  
Author(s):  
Peter Garred
Keyword(s):  
Epidemiological Studies ◽  
Mannose Binding Lectin ◽  
Host Cells ◽  
Lectin Pathway ◽  
Mannose Binding ◽  
The Stability ◽  
Genetically Determined ◽  
Micro Organisms ◽  
Binding Lectin

MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein. It binds sugar structures on micro-organisms and on dying host cells and is one of the four known mediators that initiate activation of the complement system via the lectin pathway. Common variant alleles situated both in promoter and structural regions of the human MBL gene (MBL2) influence the stability and the serum concentration of the protein. Epidemiological studies have suggested that genetically determined variations in MBL serum concentrations influence the susceptibility to and the course of different types of infectious, autoimmune, neoplastic, metabolic and cardiovascular diseases, but this is still a subject under discussion. The fact that these genetic variations are very frequent, indicates a dual role of MBL. This overview summarizes the current molecular understanding of human MBL2 genetics.

scholarly journals ON VASCULAR STENOSIS, RESTENOSIS AND MANNOSE BINDING LECTIN

2016 ◽  
Vol 29 (1) ◽  
pp. 57-59 ◽  
Author(s):  
Barbara Stadler KAHLOW ◽  
Rodrigo Araldi NERY ◽  
Thelma L SKARE ◽  
Carmen Australia Paredes Marcondes RIBAS ◽  
Gabriela Piovezani Ramos ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Mannose Binding Lectin ◽  
Mannose Binding ◽  
Vascular Stenosis ◽  
Micro Organisms ◽  
The Complement System ◽  
Binding Lectin

Mannose binding lectin is a lectin instrumental in the innate immunity. It recognizes carbohydrate patterns found on the surface of a large number of pathogenic micro-organisms, activating the complement system. However, this protein seems to increase the tissue damage after ischemia. In this paper is reviewed some aspects of harmful role of the mannose binding lectin in ischemia/reperfusion injury.

scholarly journals Potential Role of Mannose-Binding Lectin in Intrauterine Transmission of Hepatitis B Virus

2013 ◽  
Vol 66 (5) ◽  
pp. 391-393 ◽  
Author(s):  
Yuzhong Wu ◽  
Qunyan Zhou ◽  
Huihua Wang ◽  
Ting Tian ◽  
Qiuyuan Zhu ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Potential Role ◽  
Mannose Binding Lectin ◽  
Intrauterine Transmission ◽  
B Virus ◽  
Mannose Binding ◽  
Binding Lectin
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