Cancer survival in European adolescents and young adults

2003 ◽  
Vol 39 (18) ◽  
pp. 2600-2610 ◽  
Author(s):  
G. Gatta ◽  
R. Capocaccia ◽  
R. De Angelis ◽  
C. Stiller ◽  
J.W. Coebergh
2019 ◽  
Vol 111 (6) ◽  
pp. 633-634 ◽  
Author(s):  
Stuart E Siegel ◽  
Peter F Coccia ◽  
Ronald Barr ◽  
Brandon Hayes-Lattin ◽  
Archie Bleyer

2019 ◽  
Vol 8 (10) ◽  
pp. 4867-4874 ◽  
Author(s):  
Meryl D. Colton ◽  
DeLayna Goulding ◽  
Alina Beltrami ◽  
Carrye Cost ◽  
Anna Franklin ◽  
...  

2019 ◽  
Vol 121 (12) ◽  
pp. 1079-1084 ◽  
Author(s):  
Klaus Rostgaard ◽  
Henrik Hjalgrim ◽  
Laura Madanat-Harjuoja ◽  
Tom B. Johannesen ◽  
Sofia Collin ◽  
...  

Abstract Background The present study aimed to assess whether the widespread concern of inferior cancer survival in adolescents and young adults (AYAs) compared with children and adults holds true in a Nordic setting with important differences in healthcare organisation compared with the United States (e.g. free access to healthcare) and the United Kingdom (e.g. young teenagers are treated in paediatric departments). Methods Five-year relative survival was calculated for 17 diagnostic groups in patients diagnosed in 2000–2013 in three diagnostic age categories: children (0–14 years), AYAs (15–24 years) and adults (25–34 years). Results For 13 out of 17 diagnostic groups examined, there was no difference in survival between AYAs and neighbouring age categories. For acute lymphoblastic leukaemias, astrocytomas, rhabdomyosarcomas and non-rhabdomyosarcoma soft tissue sarcomas we found survival in children to be superior to that in AYAs. For these four diagnostic groups, the rate of survival improvement over three calendar periods (1980–1989, 1990–1999 and 2000–2013) was not particularly low in AYAs compared with neighbouring age categories. Conclusions The present study suggests that in an affluent setting with free access to healthcare, meaningful differences in survival between AYA patients and either childhood or adult patients are a phenomenon of the past for most AYA cancer diagnostic groups.


Thyroid ◽  
2015 ◽  
Vol 25 (6) ◽  
pp. 635-648 ◽  
Author(s):  
Theresa H.M. Keegan ◽  
Raymon H. Grogan ◽  
Helen M. Parsons ◽  
Li Tao ◽  
Michael G. White ◽  
...  

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Diana J Moke ◽  
Kaiya Tsai ◽  
Ann S Hamilton ◽  
Amie Hwang ◽  
Lihua Liu ◽  
...  

Abstract Background Although landmark studies in the 1990s demonstrated that adolescents and young adults (AYAs, ages 15–39 years) with cancer had lower survival improvement compared to other ages, therapeutic advances warrant reappraisal of those observations. We utilized more recent data to study site-specific AYA survival trends and disparities and gain a more contemporary understanding of this problem. Methods Using California Cancer Registry data from 1988 to 2014, we calculated 1) 5-year overall survival improvement for AYAs compared to other age groups; 2) hazard ratios (HRs) of death for AYAs comparing 2001–2014 with 1988–2000 stratified by site, stage, sex, age group, race and ethnicity, and socioeconomic status (SES); and 3) site-specific adjusted HRs (aHRs) for AYA risk groups and interaction analyses by time period. Results For all cancers combined, AYAs demonstrated survival improvement that exceeded all other age groups, largely due to reduced mortality in human immunodeficiency virus and acquired immunodeficiency syndrome-related cancers. The strongest predictor of death was cancer stage (aHR = 6.32 for distant vs localized, 95% confidence interval [CI] = 6.20 to 6.45). The aHR of death was statistically significantly higher for blacks (1.46, 95% CI = 1.42 to 1.50), Asian and Pacific Islanders (1.12, 95% CI = 1.09 to 1.15), and Latino whites (1.06, 95% CI = 1.04 to 1.08) compared to non-Latino whites, and was statistically significantly higher for low SES compared to high (1.31, 95% CI = 1.29 to 1.34). Survival disparities by stage, race and ethnicity, and SES worsened over time. Conclusions For AYAs in aggregate, the historical cancer survival improvement gap has been closed. However, the growing survival disparities in AYA subsets reported here, including advanced stage disease, racial and ethnic minorities, and low SES, highlight new priorities in need of increased attention, including inequities in cancer care and delivery within this vulnerable population.


2018 ◽  
Vol 111 (5) ◽  
pp. 509-518 ◽  
Author(s):  
Lihua Liu ◽  
Diana J Moke ◽  
Kai-Ya Tsai ◽  
Amie Hwang ◽  
David R Freyer ◽  
...  

Cancer ◽  
2016 ◽  
Vol 122 (7) ◽  
pp. 1009-1016 ◽  
Author(s):  
Theresa H.M. Keegan ◽  
Lynn A.G. Ries ◽  
Ronald D. Barr ◽  
Ann M. Geiger ◽  
Deborah Vollmer Dahlke ◽  
...  

Author(s):  
Marc Allroggen ◽  
Peter Rehmann ◽  
Eva Schürch ◽  
Carolyn C. Morf ◽  
Michael Kölch

Abstract.Narcissism is seen as a multidimensional construct that consists of two manifestations: grandiose and vulnerable narcissism. In order to define these two manifestations, their relationship to personality factors has increasingly become of interest. However, so far no studies have considered the relationship between different phenotypes of narcissism and personality factors in adolescents. Method: In a cross-sectional study, we examine a group of adolescents (n = 98; average age 16.77 years; 23.5 % female) with regard to the relationship between Big Five personality factors and pathological narcissism using self-report instruments. This group is compared to a group of young adults (n = 38; average age 19.69 years; 25.6 % female). Results: Grandiose narcissism is primarily related to low Agreeableness and Extraversion, vulnerable narcissism to Neuroticism. We do not find differences between adolescents and young adults concerning the relationship between grandiose and vulnerable narcissism and personality traits. Discussion: Vulnerable and grandiose narcissism can be well differentiated in adolescents, and the pattern does not show substantial differences compared to young adults.


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