The National Horizon Scanning Centre (NHSC): Early warning for new and emerging health technologies in England

2005 ◽  
Vol 9 (6) ◽  
pp. 410-413 ◽  
Author(s):  
Claire Packer
Keyword(s):  
Early Warning ◽  
Health Technologies ◽  
Horizon Scanning

Implementing Early Warning Messages on Emerging Health Technologies

1998 ◽  
Vol 14 (4) ◽  
pp. 663-670 ◽  
Author(s):  
Graham Mowatt ◽  
Mary Ann Thomson ◽  
Jeremy Grimshaw ◽  
Adrian Grant
Keyword(s):  
Health Care ◽  
Early Warning ◽  
Health Care Professionals ◽  
Implementation Strategies ◽  
Care Group ◽  
Health Technologies ◽  
Organisation Of Care ◽  
Warning Messages ◽  
Horizon Scanning ◽  
Active Implementation

AbstractThe purpose of this study was to determine how horizon-scanning organizations can encourage the implementation of recommendations contained in their early warning messages about emerging health technologies. We reviewed the conclusions of the EUR-ASSESS Project Subgroup report on dissemination and impact, an overview of systematic reviews of interventions to promote implementation of research findings by health care professionals, and various Cochrane Effective Practice and Organisation of Care Group protocols and reviews. The evidence on the effectiveness of different implementation strategies aimed at distinct target groups is of variable quality. There is some evidence from rigorous study designs on the effectiveness of strategies designed to influence the behavior of health care professionals; the quality of the evidence relating to policy makers and the general public is more limited. Horizon-scanning organizations can improve the likelihood of their recommendations being acted upon by developing active implementation strategies based on the best available evidence, establishing links with key groups, and directing early warning messages at specific target audiences. Given the relative lack of good quality evidence, it is important that implementation strategies be rigorously evaluated to determine their effectiveness.

scholarly journals Almost half of references in reports on new and emerging nondrug health technologies are grey literature

2019 ◽  
Vol 107 (1) ◽  
Author(s):  
Kelly Farrah ◽  
Monika Mierzwinski-Urban
Keyword(s):  
Medical Devices ◽  
Laboratory Tests ◽  
Evidence Synthesis ◽  
Grey Literature ◽  
Regulatory Agencies ◽  
Literature Searching ◽  
Health Technologies ◽  
Clinical Trial Registries ◽  
Horizon Scanning ◽  
The Us

Objective: The research investigated how frequently grey literature is used in reports on new and emerging nondrug health technologies, which sources are most cited, and how grey literature searching is reported.Methods: A retrospective review of references cited in horizon scanning reports on nondrug health technologies—including medical devices, laboratory tests, and procedures—was conducted. A quasi-random sample of up to three reports per agency was selected from a compilation of reports published in 2014 by international horizon scanning services and health organizations.Results: Twenty-two reports from 8 agencies were included in the analysis. On average, 47% (288/617) of references listed in the bibliographies of the horizon scanning reports were grey literature. The most frequently cited type of grey literature was information from manufacturers (30% of all grey literature references), regulatory agencies (10%), clinical trial registries (9%), and other horizon scans or evidence synthesis reports (9%). The US Food and Drug Administration (FDA) and ClincalTrials.gov were the most frequently cited specific sources, constituting 7% and 8% of grey literature references, respectively. Over two-thirds (15/22) of the analyzed reports provided some details on search methodology; all 15 of these reported searching some grey literature.Conclusions: In this sample, grey literature represented almost half of the references cited in reports on new and emerging nondrug health technologies. Of these grey literature references, almost half came from three sources: the manufacturers, ClinicalTrials.gov, and the FDA. There was wide variation in the other sources cited. Literature search methodology was often insufficiently reported for analysis.

International diffusion of new health technologies: A ten-country analysis of six health technologies

2006 ◽  
Vol 22 (4) ◽  
pp. 419-428 ◽  
Author(s):  
Claire Packer ◽  
Sue Simpson ◽  
Andrew Stevens ◽  
Keyword(s):  
United Kingdom ◽  
Early Warning ◽  
New Technologies ◽  
Health Spending ◽  
Early Warning Systems ◽  
Health Technologies ◽  
International Diffusion ◽  
The United Kingdom ◽  
Drug Eluting ◽  
Deep Brain

Objectives: The objective of this study was to examine and explain the differential international diffusion of six health innovations.Methods: A retrospective diffusion study was undertaken of sildenafil, cyclooxygenase-II (COX II) inhibitors, beta interferon, verteporfin, deep brain stimulators, and drug-eluting coronary stents in ten countries—Australia, Canada, Denmark, France, The Netherlands, Norway, Spain, Sweden, Switzerland, and the United Kingdom. We plotted diffusion curves of daily defined doses per quarter, vials or implants per million population, and examined the association between diffusion and five key variables.Results: Canada, Switzerland, and Sweden are generally high users of new technologies; Spain, Denmark, and particularly the United Kingdom are low users. Almost all countries experienced rapid adoption of sildenafil with diffusion to a similar level; there was variable adoption and diffusion of COX II inhibitors, verteporfin, and interferon beta; drug-eluting stents penetrated the market in a similar way in all but one country; and two countries had very different adoption patterns for deep brain stimulators. Above average health spending and the presence of health technology assessment (HTA) or other guidance reports are consistently associated with increased diffusion. Early warning activity and a national coverage decision being taken are more likely to be associated with a reduced diffusion.Conclusions: The significant differences in diffusion between different countries are not consistent with a neat evidence-based world. The tools available to policy makers to control diffusion (early warning systems, HTA, and a fourth hurdle) play some part in influencing diffusion but need close scrutiny of how successfully they operate.

MAKING PROCESSES RELIABLE: A VALIDATED PUBMED SEARCH STRATEGY FOR IDENTIFYING NEW OR EMERGING TECHNOLOGIES

2012 ◽  
Vol 28 (4) ◽  
pp. 452-459 ◽  
Author(s):  
Leonora Varela-Lema ◽  
Jeanette Punal-Riobóo ◽  
Beatriz Casal Acción ◽  
Alberto Ruano-Ravina ◽  
Marisa López García
Keyword(s):  
Search Strategy ◽  
Emerging Technologies ◽  
Scanning System ◽  
Free Text ◽  
Medline Search ◽  
Health Technologies ◽  
Horizon Scanning ◽  
Wide Range ◽  
Pubmed Search ◽  
Bibliographic Search

Background and Objectives:Horizon scanning systems need to handle a wide range of sources to identify new or emerging health technologies. The objective of this study is to develop a validated Medline bibliographic search strategy (PubMed search engine) to systematically identify new or emerging health technologies.Methods:The proposed Medline search strategy combines free text terms commonly used in article titles to denote innovation within index terms that make reference to the specific fields of interest. Efficacy was assessed by running the search over a period of 1 year (2009) and analyzing its retrieval performance (number and characteristics). For comparison purposes, all article abstracts published during 2009 in six preselected key research journals and eight high impact surgery journals were scanned. Sensitivity was defined as the proportion of relevant new or emerging technologies published in key journals that would be identified in the search strategy within the first 2 years of publication.Results:The search yielded 6,228 abstracts of potentially new or emerging technologies. Of these, 459 were classified as new or emerging (383 truly new or emerging and 76 new indications). The scanning of 12,061 journal abstracts identified 35 relevant new or emerging technologies. Of these, twenty-nine were located within the Medline search strategy during the first 2 years of publication (sensitivity = 83 percent).Conclusions:The current search strategy, validated against key journals, has demonstrated to be effective for horizon scanning. Even though it can require adaptations depending on the scope of the horizon scanning system, it could serve to simplify and standardize scanning processes.

OP491 Beyond Horizon-Scanning And Early Identification Of Innovative Technologies – Development Of An Active Monitoring Framework

2020 ◽  
Vol 36 (S1) ◽  
pp. 11-11
Author(s):  
Patricia Aluko ◽  
Fernando Zanghelini ◽  
Oladapo Ogunbayo
Keyword(s):  
Evidence Synthesis ◽  
Regulatory Approval ◽  
Sensitive Information ◽  
Active Monitoring ◽  
Health Technologies ◽  
Horizon Scanning ◽  
Monitoring Process ◽  
Advanced Therapies ◽  
Monitoring Framework ◽  
Completion Date

IntroductionWhile horizon-scanning systems aim to identify innovative and potentially disruptive health technologies in development, a key challenge is variation in information collation and tracking of the pace of change prior to regulatory approval. An active and efficient monitoring process is crucial for timely notification of health technology assessment (HTA) stakeholders to enhance faster market and patient access. The National Institute for Health Research Innovation Observatory (NIHRIO) identifies and notifies its key HTA stakeholders in England of technologies that are within three to five-year timeframe to regulatory approval. Regular review of each technology is required to meet this remit.MethodsA standardized monitoring framework was developed based on the knowledge and experience of the evidence synthesis specialists in NIHRIO, supplemented by literature to ensure consistency of setting review periods. This framework used predefined criteria that integrated the technology innovation (advanced therapies, orphan status, regulatory awards), trial data (phase, status, completion date, preliminary results) and estimated approval timelines obtained from the company or other sources (for example, press releases).ResultsThe framework has been piloted and early findings showed improved consistency in the monitoring process between different analysts. It ensures that each technology is reviewed at least once a year; review timelines are set at three, six, nine or twelve months based on the predefined criteria. Estimated timeframes obtained from the companies are used to triangulate and streamline review periods, improving efficiency of the monitoring process.ConclusionsFindings from the pilot work with the framework demonstrated improved consistency and efficiency of the technology monitoring process, which can be easily implemented to provide early awareness in an accurate and timely manner for HTA. This framework was designed using a systematic and transparent approach that integrated different data sources to set review periods. While most of the data used in defining the criteria are publicly available, commercially sensitive information provided by companies were also used which may not always be readily available. Implications for horizon-scanning organizations will be discussed.

scholarly journals Pharyngeal Electrical Stimulation for the Treatment of Dysphagia Associated With Neurologic Conditions

2021 ◽  
Vol 1 (9) ◽  
Author(s):  
Anusree Subramonian
Keyword(s):  
Health Care ◽  
Electrical Stimulation ◽  
Emerging Technology ◽  
Decision Makers ◽  
Health Care Decision ◽  
Health Technologies ◽  
Potential Interest ◽  
Horizon Scanning ◽  
Available Information ◽  
Care Decision

Horizon Scan reports provide brief summaries of information regarding new and emerging health technologies. These technologies are identified through the CADTH Horizon Scanning Service as topics of potential interest to health care decision-makers in Canada. This Horizon Scan summarizes the available information regarding an emerging technology, Phagenyx, a pharyngeal electrical stimulation device for the treatment of difficulty swallowing associated with neurologic conditions.

Health Technology Assessment in Malaysia: Past, Present, and Future

2019 ◽  
Vol 35 (6) ◽  
pp. 446-451 ◽  
Author(s):  
Sarimin Roza ◽  
Sabirin Junainah ◽  
Mudla Mohamed Ghazali Izzuna ◽  
Ku Abdul Rahim Ku Nurhasni ◽  
Mohd Aminuddin Mohd Yusof ◽  
...  
Keyword(s):  
Decision Making ◽  
Health Technology Assessment ◽  
Technology Assessment ◽  
Impact Evaluation ◽  
Quantitative Description ◽  
Health Technology ◽  
Health Technologies ◽  
The Past ◽  
Horizon Scanning ◽  
Report Quality

AbstractObjectivesThe aim of this study was to provide a comprehensive overview of the evolution of health technology assessment (HTA) in Malaysia over the past decade.MethodsWe described the evolution of HTA program in Malaysia based on review of administrative data, publicly available information and quantitative description of impact evaluation.ResultsHealth Technology Assessment HTA was formalized in Malaysia in 1995 as a central structure within the Ministry of Health, Malaysia in 1995. Expansion of activities demonstrated over the years including Horizon Scanning of health technologies and implementation of evidence-based Clinical Practice Guidelines. Improvement on the processes in terms of types of report, quality, monitoring, and impact evaluation as well as accessibility was also carried out. Examples of impact/influence of the reports have also been demonstrated.ConclusionsHTA program in Malaysia has evolved over the past decades. Its role in policy formulation and decision making of health technologies has become more significant over the years and is foreseen to be bigger in the future. As a trusted source of evidence, HTA in Malaysia will continue to strengthen the health system by advocating informed decision making and value-based medicine. As other countries in this region is trying to establish their own HTA processes and procedures, this review on the evolution of the HTA program in Malaysia might give some insights on developing a sustainable HTA program.

OP107 The Stakeholder Involvement Strategy For Horizon Scanning In Korea

2018 ◽  
Vol 34 (S1) ◽  
pp. 40-40
Author(s):  
Jooyeon Park ◽  
Eunjung Park ◽  
Chaemin Shin
Keyword(s):  
Social Impact ◽  
New Technologies ◽  
Stakeholder Involvement ◽  
Scanning System ◽  
Final Report ◽  
Health Technologies ◽  
Horizon Scanning ◽  
Potential Impact ◽  
Scanning Systems ◽  
Horizon Scanning System

Introduction:As science advances the number of newly developed health technologies increases, but the lifecycles of health technologies becomes shorter. Thus, the importance of horizon scanning systems for identifying promising new health technologies and evaluating their potential impact is increasing. Engaging and collecting opinions from various stakeholders in this search process is very important. The purpose of this study was to develop a strategy for involving various stakeholders in all steps of the horizon scanning system in Korea.Methods:The horizon scanning system consists of five steps: identification, filtration, prioritization, assessment, and dissemination. We identified the stakeholders to be considered at each stage, and examined who would be involved and how. In addition, we planned how to synthesize and apply stakeholder opinions and to test the feasibility of these methods by using them in a horizon scanning system.Results:In the identification stage, developers, health professionals, and consumers suggested new and emerging health technologies to investigate. In the filtration stage, the person in charge of licensing judged the technologies based on appropriateness, innovativeness, and potential of market entry. In the prioritization phase, experts from eight to ten related fields (clinical, health technology and drugs, policy, methodology, patient organizations, etc.) participated and judged the technologies according to seven criteria (burden of disease, clinical impact, innovativeness, economic impact, acceptability, social impact, and evidence). In the assessment stage, between one and four clinical and methodological experts assessed the potential impact of the selected promising health technologies using seven evaluation items (unmet needs, improved patient health, health equity, change in medical behaviors, acceptability with respect to the patient and clinical condition, change in medical costs, and social, ethical, political, and cultural aspects). Before its dissemination, the final report was delivered to relevant industries for feedback (with particular emphasis on accuracy of data on the technology).Conclusions:There are many stakeholders in the horizon scanning system for new and emerging health technologies, depending on the healthcare system, policy, environment, etc. This study confirmed that stakeholder opinions on new technologies can vary. In addition, standards of social value judgment may change over time. It is therefore very important for horizon scanning systems to engage various stakeholders, collect their opinions, and make rational scientific decisions.

EARLY ASSESSMENT AND PREDICTION OF POTENTIAL IMPACT OF THE IMPLANTATION OF POLYURETHANE SCAFFOLD IN PARTIAL MENISCAL LESIONS: A PILOT HORIZON SCANNING ACTIVITY IN SOUTH KOREA

2015 ◽  
Vol 31 (6) ◽  
pp. 380-389 ◽  
Author(s):  
Ji Yun Tark ◽  
Ji-young Jeong ◽  
Min Lee ◽  
Eunjung Park ◽  
Jooyeon Park ◽  
...  
Keyword(s):  
Adverse Events ◽  
Healthcare System ◽  
Case Series ◽  
Current Evidence ◽  
Early Assessment ◽  
Health Technologies ◽  
Polyurethane Scaffold ◽  
Horizon Scanning ◽  
Meniscal Lesions ◽  
Potential Impact

Objectives: The aim of this study was to predict the potential impact of the introduction of implantation of polyurethane scaffold for the treatment of partial meniscal lesions in the South Korean healthcare system.Methods: The horizon scanning process was used to select a target technology and assess its potential impacts on patients and the Korean healthcare system. We identified and filtered research-phase health technologies that are not listed yet in Korean, but appear promising. After a process of prioritization, we chose the implantation of polyurethane scaffolds as a target technology. Then, through the procedures of assessment and peer review, we analyzed current evidence and its predicted potential impacts.Results: There were eight studies included in the review: one prospective cohort and seven case-series studies. Six revealed significant improvements in function and pain relief. Of the six studies, which reported safety endpoints, four stated no major postoperative complications related to scaffold, and two reported adverse events and serious adverse events such as pain, joint swelling, et cetera. We also included the potential impact of this technology based on the experts’ consultation. They all agreed that it would satisfy the diverse needs of patients and fulfill clinical needs. However, the majority of related clinical studies were based on short-term follow-up observations without any validation process involving comparison with control groups.Conclusions: Through a horizon scanning activity, we found that the implantation of polyurethane scaffolds is a promising technology to resolve articular cartilage defects; however, long-term evidence with comparison groups for safety and effectiveness is required.

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