The relationship between height and neighborhood context across racial/ethnic groups: A multi-level analysis of the 1999–2004 U.S. National Health and Nutrition Examination Survey

2013 ◽  
Vol 11 (1) ◽  
pp. 30-41 ◽  
Author(s):  
D. Phuong Do ◽  
Daphne C. Watkins ◽  
Martin Hiermeyer ◽  
Brian K. Finch
Keyword(s):  
Ethnic Groups ◽  
National Health ◽  
Neighborhood Context ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
Multi Level ◽  
The Relationship ◽  
Racial Ethnic ◽  
Level Analysis

scholarly journals Association of Urinary Phthalate Metabolites With Erectile Dysfunction in Racial and Ethnic Groups in the National Health and Nutrition Examination Survey 2001-2004

2016 ◽  
Vol 11 (3) ◽  
pp. 576-584 ◽  
Author(s):  
David S. Lopez ◽  
Shailesh Advani ◽  
Konstantinos K. Tsilidis ◽  
Run Wang ◽  
Jacques Baillargeon ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Ethnic Groups ◽  
National Health ◽  
Mexican Americans ◽  
Endocrine Disrupting Compounds ◽  
Computer Assisted ◽  
Nutrition Examination Survey ◽  
Phthalate Metabolites ◽  
Health And Nutrition ◽  
Racial Ethnic

Phthalates are endocrine-disrupting compounds detectable in more than 75% of the U.S. population with differential distributions across racial and ethnic groups, and they have been linked with reduced levels of serum testosterone. This study aims to investigate the associations of phthalate metabolites with erectile dysfunction (ED) and to determine whether these associations vary by race/ethnicity among men in the United States. Analyzed data for 12 phthalate metabolites from 3,746 men (≥20 years old), who participated in the National Health and Nutrition Examination Survey 2001-2004 cross-sectional study, were included. Metabolites included MBP, MCHP, MEP, MEHP, MiNP, MBzP, MMP, MCPP, MEHHP, MEOHP, MiBP, and MECPP. Racial/ethnic groups included non-Hispanic Blacks ( n = 770), non-Hispanic Whites ( n = 2,147), and Mexican Americans ( n = 829). ED was assessed by a single question during a self-paced, computer-assisted self-interview. In racial/ethnic stratified analyses, there were higher MBP and MBzP concentrations that had a strong-dose response association with lower prevalence odds of ED among Mexican Americans, ptrend < .01, and ptrend = .03, respectively. Similarly, a significant inverse association between MEHHP and likelihood of ED among non-Hispanic Black men ( ptrend < .04) was observed. Furthermore, significant inverse associations between higher concentrations of phthalates and ED were identified only in minority populations. Further investigations, particularly prospective studies, are warranted to determine the role of phthalates on the biological mechanism(s) associated with ED. A focus may be placed on testosterone levels which are suggested to be affected by phthalates, and also low levels of testosterone are suggested to increase the risk of ED.

scholarly journals Gender Dictates the Relationship between Serum Lipids and Leukocyte Counts in the National Health and Nutrition Examination Survey 1999–2004

2019 ◽  
Vol 8 (3) ◽  
pp. 365 ◽  
Author(s):  
Catherine Andersen ◽  
Terrence Vance
Keyword(s):  
Total Cholesterol ◽  
National Health ◽  
Blood Lymphocyte ◽  
Serum Lipids ◽  
Lipid Lowering ◽  
Nutrition Examination Survey ◽  
Men And Women ◽  
Health And Nutrition ◽  
Leukocyte Counts ◽  
The Relationship

Dyslipidemias and leukocytosis are associated with cardiovascular disease and immune disorders. Mechanistic studies have shown lipoprotein metabolism to play a significant role in the regulation of atherosclerosis development and leukocyte activation, whereas lipid-lowering treatments have been shown to exert beneficial anti-inflammatory and immunomodulatory effects in clinical trials. However, the relationship between clinical markers of lipid metabolism and leukocyte counts has not been extensively evaluated at the population level. We aimed to determine whether clinical blood lipid measures are associated with leukocyte counts in the general U.S. population represented in the National Health and Nutrition Examination Survey (NHANES) 1999–2004, and whether differences exist between men and women (n = 5647). We observed a strong positive linear trend between serum triglycerides vs. blood lymphocyte and basophil counts in both men and women, whereas a positive trend between monocytes vs. triglycerides and lymphocytes vs. total cholesterol and LDL-cholesterol (LDL-C) was only detected in women. Conversely, HDL-C was inversely associated with a greater number of leukocyte subsets in men, whereas inverse trends between HDL-C vs. lymphocytes were observed in both men and women. In multiple regression models, a 10% increase in total cholesterol, LDL-C, and triglycerides was associated with a predicted 1.6%, 0.6%, and 1.4% increase in blood lymphocyte counts in women, respectively, whereas no relationship was observed in men. In both men and women, a 10% increase in triglycerides was additionally associated with higher lymphocyte, neutrophil, and basophil counts, whereas 10% increases in HDL-cholesterol were associated with significantly lower lymphocyte, neutrophil, eosinophil, and basophil counts in men, in addition to lower lymphocyte and monocyte counts in women. These findings suggest that clinical lipid markers may be used to predict blood leukocyte distributions, and that a gender-specific relationship exists between distinct classes of serum lipids and immune cell subsets.

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