Clinical Utility of Measuring Epicardial Adipose Tissue Thickness with Echocardiography Using a High-Frequency Linear Probe in Patients with Coronary Artery Disease

2015 ◽  
Vol 28 (10) ◽  
pp. 1240-1246.e1 ◽  
Author(s):  
Yukina Hirata ◽  
Hirotsugu Yamada ◽  
Kenya Kusunose ◽  
Takashi Iwase ◽  
Susumu Nishio ◽  
...  
PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e110005 ◽  
Author(s):  
Fabien A. Picard ◽  
Pascal Gueret ◽  
Jean-Pierre Laissy ◽  
Stéphane Champagne ◽  
Florence Leclercq ◽  
...  

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Yukia Hirata ◽  
Hirotsugu Yamada ◽  
Kenya Kusunose ◽  
Susumu Nishio ◽  
Mika Bando ◽  
...  

Introduction: Epicardial adipose tissue(EAT), which is thought to be an ectopic adipose tissue, has been paid attention in association with coronary artery disease (CAD). Hypothesis: We hypothesized that EAT in anterior interventricular groove (AIG) obtained by echocardiography can be an additional marker over classical risk factors for prediction of CAD. Methods: We enrolled 311 patients (mean age 67±11 yrs, 208 men) who underwent coronary angiography between December 2011 and December 2013 at our hospital. We measured EAT thickness on the AIG and right ventricular free wall (EAT-RV) using high-frequency linear probe. Subjects were divided into 2 groups with and without significant coronary stenosis (≧75%) from coronary angiography. The performance of clinical risk factors (including age, male gender, body mass index (BMI), diabetes mellitus, hypertension, dyslipidemia, and smoking) plus various combinations of EAT thickness measurements for predicting CAD was assessed using the area under the curve (AUC) in ROC analysis. Results: The EAT-AIG thickness was significantly greater in the CAD group than that in the non-CAD group (8.3±3.0 vs. 6.3±2.5 mm, p<0.001), and there as also significant difference in the EAT-RV between the two groups (5.0±2.1 vs. 4.4±2.3 mm, p=0.009). Adding the EAT-AIG thickness over classical risk factors improved prediction of presence CAD (AUC 0.692 vs. 0.788, p<0.001), while the EAT-RV did not (AUC 0.692 vs. 0.704, p=0.343). Conclusions: Echocardiographic EAT-AIG thickness was greater in the CAD group than the non-CAD group. This non-invasive index may have clinical potential as a maker for predicting coronary atherosclerosis.


2018 ◽  
Vol 08 (03) ◽  
pp. 155-158
Author(s):  
Sadaf Shaheen ◽  
Sahrish Mukhtar ◽  
Iffat Raza ◽  
Bashir Sheikh

Objectives: The aim of this study was to measure the Epicardial Adipose Tissue thickness through echocardiography in healthy adults and coronary artery disease patients and to make its association with age and gender. Methods: It was a case control study. A total of 315 samples including 159 cases of coronary artery disease and 156 asymptomatic individuals for coronary artery disease underwent echocardiography for Epicardial Adipose Tissue thickness measurement. Results: Mean Epicardial Adipose Tissue (EAT) in the study was found to be 15.45 ± 7.16 mm. Cases had significantly higher EAT 16.77 ±9.80mm as compared to controls 14.13 ± 4.52 mm (P=0.02). EAT thickness increased significantly with age (P=0.004). There was no significant difference of EAT (P=0.999) in both the genders. Conclusion: The mean EAT thickness is significantly higher in our study population as compared to previous studies. The mean EAT thickness was same in both males and females of our study. There was no significant difference in EAT of both genders.


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