Risk Stratification in Chronic Heart Failure: Independent and Incremental Prognostic Value of Echocardiography and Brain Natriuretic Peptide and its N-terminal Fragment

2006 ◽  
Vol 19 (5) ◽  
pp. 522-528 ◽  
Author(s):  
Christian Bruch ◽  
Markus Rothenburger ◽  
Michael Gotzmann ◽  
Juergen Sindermann ◽  
Hans H. Scheld ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Risk Stratification ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Prognostic Value ◽  
Terminal Fragment ◽  
Incremental Prognostic Value

Prognostic value of brain natriuretic peptide and enhanced ventilatory response to exercise in patients with chronic heart failure

2008 ◽  
Vol 3 (4) ◽  
pp. 331-337 ◽  
Author(s):  
Angela Beatrice Scardovi ◽  
Renata De Maria ◽  
Andrea Celestini ◽  
Claudio Coletta ◽  
Nadia Aspromonte ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Prognostic Value ◽  
Ventilatory Response ◽  
Response To Exercise

scholarly journals A. Diagnostic and prognostic value of detection of the N-terminal fragment of brain natriuretic peptide in type 2 diabetes mellitus

2017 ◽  
Vol 95 (6) ◽  
pp. 553-557
Author(s):  
A. F. Verbovoy ◽  
Natal’ya A. Barabanova
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Glucose ◽  
Chronic Heart Failure ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Terminal Fragment

Detction of chronic heart failure at the stage of reversible changes can prevent the development of cardiovascular complications, reduce morbidity and mortality in patients with type 2 diabetes mellitus. The aim of our study was to explore the level of N-terminal fragment of pro-brain natriuretic peptide (NT-proBNP) and to evaluate the possibility of using this marker in diagnostics of chronic heart failure in patients with type 2 diabetes. The study included 60 patients with type 2 diabetes and concomitant chronic heart failure. All patients underwent echocardiography, blood glucose and glycated hemoglobin, creatinine, and NT-proBNP measurement. All patients with diabetes mellitus were shown to have elevated NT-proBNP levels in comparison with the control group. We established negative correlation of this parameter with the left ventricular ejection fraction and inverse correlation between NT-proBNP and blood glucose. The study confirmed the value of NT-proBNP measurement for diagnostics of CHF but demonstrated low specificity of this test for the assessment of severity (functional class) of CHF in patients with type 2 diabetes.

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