Short-term weight gain velocity in infants with congenital diaphragmatic hernia (CDH)

2017 ◽  
Vol 106-107 ◽  
pp. 7-12 ◽  
Author(s):  
Jason Gien ◽  
Karna Murthy ◽  
Eugenia K Pallotto ◽  
Beverly Brozanski ◽  
Louis Chicoine ◽  
...  
2015 ◽  
Vol 167 (3) ◽  
pp. 762-764 ◽  
Author(s):  
Emma Olson ◽  
Leslie A. Lusk ◽  
Jeffrey R. Fineman ◽  
Laura Robertson ◽  
Roberta L. Keller

2017 ◽  
Vol 15 (2) ◽  
pp. 30-32
Author(s):  
Seyyed Javad Nasiri ◽  
Maryam Ghavami Adel ◽  
Mohammad Reza Keramati

Background: The mortality rate of Congenital Diaphragmatic Hernia (CDH) is still high in many centers. Most important factors influencing the outcome are pulmonary hypoplasia and associated anomalies. In this study, postnatal factors affecting short term outcome of patients with isolated CDH will be studied in an educational children hospital.Methods : This is a historical cohort study, on newborns with isolated posterolateral congenital diaphragmatic hernia from 2005 to 2015. Relative risks of variables for the short term outcome (Discharged alive or expired) were calculated. We also analyzed the highest PaO2, which was measured during the course of the management in the patients. Location of the liver and stomach were detected, too.Results: Fifty-three patients were studied, including 28(52.8%) male and 25(47.2%) female. Mean Gestational Age (GA) was 38 weeks (Range: 33-40) and mean body weight was 3001.22 (Range: 1300 – 4200) grams. Forty-two (79.2%) presented with left sided hernia, and 10(18.9%) had right sided defect. Thirty-two (60.4 %) patients discharged alive, and 21(39.6%) expired. Mortality rate for right sided hernias was 70% (7/10), and for left sided ones was 31% (13/42). Sex, weight, GA, stomach and liver herniation had no significant effect on survival. Side of involvement, time of presentation (Onset of symptoms), first measured PaO2, and first measured PaCO2, had significant influences on survival.Conclusion: According to our analysis, side of hernia, time of onset of symptoms, and initial PaO2 and PaCO2 are factors predicting survival in children with congenital diaphragmatic hernia. Although, we may predict the early outcome of the patients, more studies are needed in this regard.Chatt Maa Shi Hosp Med Coll J; Vol.15 (2); Jul 2016; Page 30-32


2015 ◽  
Vol 32 (11) ◽  
pp. 1038-1044 ◽  
Author(s):  
Karna Murthy ◽  
Beverly Brozanski ◽  
Jason Gien ◽  
Natalie Rintoul ◽  
Sarah Keene ◽  
...  

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Emam D ◽  
◽  
Van der Veeken L ◽  
El Badry A ◽  
Elattar A ◽  
...  

Congenital Diaphragmatic Hernia (CDH) is a rare congenital anomaly characterized by a defect in the diaphragm, which permits abdominal organs to herniate into the thorax. This causes lung hypoplasia and at birth, children with CDH experience respiratory distress and pulmonary hypertension. Despite optimal neonatal treatment, CDH is still associated with a high mortality and morbidity. In severe cases, Fetal Intervention (FETO) may alter the natural course of this disease. Herein we describe the rationale, action mechanism and technique to perform this intervention. Despite hope giving results, this technique remains investigational for left sided CDH. However, an increased survival may come at the cost of increased morbidity. Children born with CDH are at increased risk for long and short-term morbidity, including neurodevelopmental problems. Until now, there are still uncertainties about the severity and prevalence of neurologic morbidity. Furthermore, it remains uncertain if these problems are already present prenatally and if a prenatal intervention influence this.


2015 ◽  
Vol 166 (2) ◽  
pp. 251-256.e1 ◽  
Author(s):  
Leslie A. Lusk ◽  
Katherine C. Wai ◽  
Anita J. Moon-Grady ◽  
Martina A. Steurer ◽  
Roberta L. Keller

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