Potential benefits of physical activity during pregnancy for the reduction of gestational diabetes prevalence and oxidative stress

2016 ◽  
Vol 94 ◽  
pp. 57-62 ◽  
Author(s):  
Marcela Cid ◽  
Marcelo González
Keyword(s):  
Oxidative Stress ◽  
Physical Activity ◽  
Gestational Diabetes ◽  
Diabetes Prevalence ◽  
Potential Benefits ◽  
And Oxidative Stress

Comparison of Salivary Antioxidants and Oxidative Stress Status in Gestational Diabetes Mellitus and Healthy Pregnant Women

2020 ◽  
Vol 20 ◽  
Author(s):  
Fatemeh Ahmadi-Motamayel ◽  
Shima Fathi ◽  
Mohammad Taghi Goodarzi ◽  
Shiva Borzouei ◽  
Jalal Poorolajal ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Pregnant Women ◽  
Oxidative Stress Markers ◽  
Blood Samples ◽  
Stress Markers ◽  
Total Antioxidant ◽  
Total Oxidative Stress ◽  
And Oxidative Stress

Background: One of the most common complications of pregnant women is gestational diabetes mellitus (GDM). Oxidative stress can play an important role in GDM. Objective: The aim of this study was to evaluate salivary antioxidants and oxidative stress markers in GDM. Method: Twenty pregnant women with GDM and 20 healthy pregnant women with normal blood glucose test participated in this study. Five mL of unstimulated saliva samples were collected. Spectrophotometric assay was carried out for sialochemical analysis. Stata software was used for data analysis. Results: The GDM group exhibited no significant difference in salivary total antioxidant capacity and malondialdehyde compared to the healthy control group. All of antioxidants markers, the uric acid, total antioxidant, peroxidase and catalase, decreased in GDM group that the difference of peroxidase and catalase was statistically significant. All of oxidative stress markers, the salivary malondyaldehid, total oxidative stress and total thiol, increased in GDM group. GDM group exhibited significantly higher salivary total oxidative stress levels. Conclusion: Catalase level was significantly lower and total oxidative stress was significantly higher. These two markers might have significant importance and might exhibit early changes compared to other factors in GDM. . Some of salivary antioxidants might have diagnostic, prognostic or therapeutic implications in GDM. Other studies with large sample size on salivary and blood samples need to be done to confirm this properties and salivary samples using instead of blood samples in GDM biomarkers changes.

scholarly journals A Short Overview of Changes in Inflammatory Cytokines and Oxidative Stress in Response to Physical Activity and Antioxidant Supplementation

Antioxidants ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 886 ◽  
Author(s):  
Shima Taherkhani ◽  
Katsuhiko Suzuki ◽  
Lindy Castell
Keyword(s):  
Oxidative Stress ◽  
Physical Activity ◽  
Inflammatory Cytokines ◽  
Muscle Metabolism ◽  
Exercise Protocol ◽  
Level Of Training ◽  
Type Of Exercise ◽  
Antioxidant Supplements ◽  
And Oxidative Stress

Excessive release of inflammatory cytokines and oxidative stress (OS) are triggering factors in the onset of chronic diseases. One of the factors that can ensure health in humans is regular physical activity. This type of activity can enhance immune function and dramatically prevent the spread of the cytokine response and OS. However, if physical activity is done intensely at irregular intervals, it is not only unhealthy but can also lead to muscle damage, OS, and inflammation. In this review, the response of cytokines and OS to exercise is described. In addition, it is focused predominantly on the role of reactive oxygen and nitrogen species (RONS) generated from muscle metabolism and damage during exercise and on the modulatory effects of antioxidant supplements. Furthermore, the influence of factors such as age, sex, and type of exercise protocol (volume, duration, and intensity of training) is analyzed. The effect of antioxidant supplements on improving OS and inflammatory cytokines is somewhat ambiguous. More research is needed to understand this issue, considering in greater detail factors such as level of training, health status, age, sex, disease, and type of exercise protocol.

Iron and Oxidative Stress in Gestational Diabetes

2017 ◽  
pp. 479-491
Author(s):  
Isabelle Hininger-Favier ◽  
Jean-Marc Moulis ◽  
Jean-Marc Ayoubi
Keyword(s):  
Oxidative Stress ◽  
Gestational Diabetes ◽  
And Oxidative Stress

scholarly journals Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?

2020 ◽  
Vol 13 (10) ◽  
pp. 306 ◽  
Author(s):  
Stephanie Kourakis ◽  
Cara A. Timpani ◽  
Judy B. de Haan ◽  
Nuri Gueven ◽  
Dirk Fischer ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dimethyl Fumarate ◽  
Immune Mediated ◽  
Relapsing Remitting ◽  
Favourable Safety ◽  
Potential Benefits ◽  
Monomethyl Fumarate ◽  
Relapsing Remitting Multiple Sclerosis ◽  
And Oxidative Stress ◽  
Acid Esters

Fumaric acid esters (FAEs) are small molecules with anti-oxidative, anti-inflammatory and immune-modulating effects. Dimethyl fumarate (DMF) is the best characterised FAE and is approved and registered for the treatment of psoriasis and Relapsing-Remitting Multiple Sclerosis (RRMS). Psoriasis and RRMS share an immune-mediated aetiology, driven by severe inflammation and oxidative stress. DMF, as well as monomethyl fumarate and diroximel fumarate, are commonly prescribed first-line agents with favourable safety and efficacy profiles. The potential benefits of FAEs against other diseases that appear pathogenically different but share the pathologies of oxidative stress and inflammation are currently investigated.

scholarly journals Lipid profile, apolipoprotein A-I and oxidative stress in professional footballers, sedentary individuals, and their relatives

2011 ◽  
Vol 55 (2) ◽  
pp. 121-126 ◽  
Author(s):  
Aline Margioti Zanella ◽  
Marcelo Arruda Nakazone ◽  
Marcela Augusta Souza Pinhel ◽  
Dorotéia Rossi Silva Souza
Keyword(s):  
Oxidative Stress ◽  
Physical Activity ◽  
Physical Exercise ◽  
Lipid Profile ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
Beneficial Effects ◽  
Apolipoprotein A ◽  
And Oxidative Stress ◽  
Cholesterol Fraction

OBJECTIVE: To evaluate whether lipid profile (LP), apolipoprotein A-1 (apo A-I) and malondialdehyde (MDA) have any relationship with physical exercise by comparing the groups of footballers (FG) with sedentary individuals (CG) and their relatives (RFG and RCG). SUBJECTS AND METHODS: Twenty individuals from FG and CG, 60 from RFG, and 57 from RCG were studied. RESULTS: FG showed lower levels of total cholesterol (119.5 ± 37.9 mg/dL), LDL-cholesterol fraction (53.6 ± 30.3), apo A-I (116.7 ± 11.9), and higher level of HDL-cholesterol fraction (HDLc) (49.7 ± 8.5) compared to RFG (148.3 ± 36.9, P = 0.02; 82.4 ± 37.7, P < 0.01; 124.6 ± 10.2, P = 0.03; and 42.7 ± 7.7, P < 0.01; respectively). Moreover, FG had reduced levels of MDA (101.0 ± 77.0 ng/mL) compared to CG (290.0 ± 341.0, P = 0.03) and RFG (209.9 ± 197.5, P = 0.04). CONCLUSIONS: These results suggest an association between physical exercise and lower levels of MDA in FG. Physical activity seems to promote beneficial effects on the LP regardless of the genetic influence considering HDLc levels.

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