Magnesium sulfate exposure increases fetal blood flow redistribution to the brain during acute non-acidemic hypoxemia in goats

2006 ◽  
Vol 82 (9) ◽  
pp. 597-602 ◽  
Author(s):  
Shigeki Tanaka ◽  
Hiroshi Sameshima ◽  
Tsuyomu Ikenoue ◽  
Hiroshi Sakamoto
Keyword(s):  
Blood Flow ◽  
Magnesium Sulfate ◽  
Fetal Blood ◽  
The Brain ◽  
Blood Flow Redistribution

Ultrasound Measurements of Intracranial Structures in Growth-Restricted Neonates with Fetal Blood Flow Redistribution: A Pilot Observational Study

Neonatology ◽  
2020 ◽  
Vol 117 (4) ◽  
pp. 446-452
Author(s):  
Pramod Pharande ◽  
Mohan Krishnamurthy ◽  
Gillian Whiteley ◽  
Arun Sasi ◽  
Atul Malhotra
Keyword(s):  
Blood Flow ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Brain Structures ◽  
Cranial Ultrasound ◽  
Fetal Blood ◽  
The Impact ◽  
The Brain ◽  
Blood Flow Redistribution

<b><i>Background:</i></b> Fetal growth restriction (FGR) is associated with neonatal and long-term neuro-morbidity. Preferential redistribution of blood flow to the brain is a common antenatal adaptation in FGR. The impact of this “brain sparing,” which may signify severity of FGR, on the growth of brain structures has not been studied. <b><i>Aim:</i></b> To compare corpus callosum (CC), cerebellar, and ventricular measurements of FGR neonates with evidence of fetal blood flow redistribution with those of gestation-matched appropriately grown (AGA) neonates. <b><i>Methods:</i></b> This was a pilot, prospective observational study conducted at a tertiary level neonatal unit in Melbourne, Australia. Cranial ultrasound was done between days 1 and 3 of life in FGR and AGA neonates. <b><i>Results:</i></b> Cranial ultrasound on 20 FGR, gestation (mean ± SD) 31.4 ± 3.1 weeks, weight 1,205 ± 463 g, and 20 AGA neonates, 31.1 ± 3.0 weeks, 1,668 ± 490 g, was performed. CC length was significantly decreased in FGR neonates as compared to AGA neonates (35.28 ± 3.47 vs. 38.83 ± 4.05 mm, <i>p</i> = 0.0002). CC was significantly thinner at genu (3.36 ± 0.66 vs. 4.04 ± 0.83 mm, <i>p</i> = 0.007), body (1.97 ± 0.36 vs. 2.27 ± 0.39 mm, <i>p</i> = 0.02), and splenium (4.07 ± 0.76 vs. 4.72 ± 0.75 mm, <i>p</i> = 0.003) in FGR vs. AGA neonates. CC-fastigium length was also significantly decreased (39.65 ± 3.87 vs. 41.96 ± 4.50 mm, <i>p</i> = 0.04). Similarly, FGR neonates showed decreased transverse cerebellar diameter (36.15 ± 5.51 vs. 38.81 ± 7.21 mm, <i>p</i> = 0.02), but ventricular measurements were comparable. In multivariate analysis, these differences were evident independent of the birth weight. <b><i>Conclusions:</i></b>CC and cerebellar measurements are significantly smaller in FGR neonates with fetal blood flow redistribution, which warrants further study.

scholarly journals Influence of fetal blood flow redistribution on fetal and childhood growth and fat distribution: the Generation R Study

2016 ◽  
Vol 123 (13) ◽  
pp. 2104-2112 ◽  
Author(s):  
MN Kooijman ◽  
R Gaillard ◽  
IKM Reiss ◽  
A Hofman ◽  
EAP Steegers ◽  
...  
Keyword(s):  
Blood Flow ◽  
Fat Distribution ◽  
Fetal Blood ◽  
Childhood Growth ◽  
Blood Flow Redistribution

scholarly journals Prenatal Ambient Air Pollutants Influence Fetal Blood Flow and Shunting to the Brain in the Third Trimester

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
C.V. Breton ◽  
A. Peterson ◽  
R. Habre ◽  
F. Lurmann ◽  
M. Amin ◽  
...  
Keyword(s):  
Blood Flow ◽  
Air Pollutants ◽  
Ambient Air ◽  
Fetal Blood ◽  
Third Trimester ◽  
The Third ◽  
Ambient Air Pollutants ◽  
The Brain

scholarly journals OC069: New view on fetal blood flow redistribution

2004 ◽  
Vol 24 (3) ◽  
pp. 235-235
Author(s):  
K. Vetter ◽  
Ö. Kilavuz
Keyword(s):  
Blood Flow ◽  
Fetal Blood ◽  
Blood Flow Redistribution ◽  
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