Trans fatty acids and lipid profile: A serious risk factor to cardiovascular disease, cancer and diabetes

2019 ◽  
Vol 13 (2) ◽  
pp. 1643-1647 ◽  
Author(s):  
Md. Ashraful Islam ◽  
Mohammad Nurul Amin ◽  
Shafayet Ahmed Siddiqui ◽  
Md. Parvez Hossain ◽  
Farhana Sultana ◽  
...  
2012 ◽  
pp. 307-318
Author(s):  
Corinne Malpuech-Brugère ◽  
Béatrice Morio ◽  
Ronald P. Mensink

Author(s):  
Salma Hussein Elhassan ◽  
Bader Eldien Hassan Elabid ◽  
Sara osman Yousif

Background: Type 2 diabetes mellitus is an independent risk factor for cardiovascular disease and the risk for cardiovascular disease is increased three to four fold in type 2 diabetes mellitus as compared to non-diabetic population. Hyperuricaemia has been reported to be a potential risk factor for cardiovascular disease in type 2 diabetes mellitus. The objective of this study was to assess the plasma level of urate in Sudanese patients with type 2 diabetes in comparison with apparently healthy (non-diabetic) volunteers as controls.Methods: This is a descriptive, cross- sectional and hospital-based study conducted during the period from March to May 2011 in Jabir Abu Elez diabetic center and Nurein medical center, both in Khartoum state, Sudan. The study group included 52 NIDDM cases and 30 healthy controls of either sex matched for age and gender. Fasting venous samples were collected from both cases and controls. Serum levels of uric acid, and lipid profile were assayed using commercial reagent kits from Biosystem Company.Results: In the current study there was a significant increase in plasma urate in type 2 diabetic patients as compared to the control group. There was a significant increase in lipid profile with exception to high density lipoprotein which was significantly reduced. There was insignificant correlation of plasma urea, and lipid profile with both; body mass index and the duration of diabetes.Conclusion: Hyperuricemia is significantly associated with type 2 diabetes mellitus and can increase the morbidity and mortality of diabetes if not managed in time. Elevated plasma urate levels are associated with increased risk of cardiovascular mortality in type 2 diabetes.


2008 ◽  
Vol 87 (3) ◽  
pp. 593-599 ◽  
Author(s):  
Annie Motard-Bélanger ◽  
Amélie Charest ◽  
Geneviève Grenier ◽  
Paul Paquin ◽  
Yvan Chouinard ◽  
...  

2006 ◽  
Vol 354 (15) ◽  
pp. 1601-1613 ◽  
Author(s):  
Dariush Mozaffarian ◽  
Martijn B. Katan ◽  
Alberto Ascherio ◽  
Meir J. Stampfer ◽  
Walter C. Willett

Cardiology ◽  
2017 ◽  
Vol 138 (4) ◽  
pp. 254-258 ◽  
Author(s):  
Mateusz M. Wilczek ◽  
Robert Olszewski ◽  
Andrzej Krupienicz

Hydrogenated oils containing trans-fatty acids (TFA) are used to produce margarine and various processed foods. TFA affect serum lipid levels, fatty acid metabolism, and endothelial function. High TFA intake is linked to increased all-cause mortality, coronary heart disease mortality, and cardiovascular disease (CVD) incidence. Denmark was the first country to introduce a law that limited TFA content in food; this action led to lower CVD mortality. So far 7 European countries have followed this practice, in a few others the food industry voluntarily reduced TFA use. The issue remains mostly unaddressed in the rest of the world. Legal TFA limits should be commonly established as they are the optimal solution considering both CVD prevention and the associated cost savings in public healthcare.


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