Quantitative vibration perception threshold in assessing diabetic neuropathy: Is the cut-off value lower for Indian Subjects? [Q-VADIS Study]

2012 ◽  
Vol 6 (2) ◽  
pp. 85-89 ◽  
Author(s):  
Samit Ghosal ◽  
Jeff Stephens ◽  
Aninda Mukherjee
2018 ◽  
Vol 14 (1) ◽  
pp. 16-21 ◽  
Author(s):  
Jennefer B. J. Zwaferink ◽  
Juha M. Hijmans ◽  
Claudia M. Schrijver ◽  
Laura K. Schrijver ◽  
Klaas Postema ◽  
...  

Background: Mechanical noise may improve somatosensation at the dorsal side of the foot, but the effect at the plantar side of the foot, the side most at risk for foot ulceration, is unknown. Moreover, techniques used in research so far have several problems that limit applicability in daily practice. Piezoelectric actuators may provide mechanical noise with better clinical applicability. We assessed the effects of piezoelectric actuators generating mechanical noise on the vibration perception threshold (VPT) at the plantar side of the foot in people with diabetic neuropathy. Methods: Double-blind within-subjects design in a controlled laboratory setting including participants with diabetic neuropathy (N = 40; 18 male; mean age 69.6 years; mean duration of diabetes 14.1 years; mean BMI 30.5). VPT was measured at three plantar foot locations with and without mechanical noise applied via piezoelectric actuators. Results: Mechanical noise improved VPT at metatarsophalangeal joint (MTP) 1 (left 39.3V vs 43.5V; right 39.0 vs 42.6 V), MTP5 (left 37.5V vs 41.7V; right 34.5V vs 40.8V) and the heel (left 40.0V vs 44.0V; right 39.3V vs 41.0V), all P < .001. Conclusions: Mechanical noise improves VPT at the plantar side of the foot in people with diabetic neuropathy. This is an important step for further development of insoles using mechanical noise that may have the potential to improve VPT and decrease the risk of foot ulceration.


2001 ◽  
Vol 18 (6) ◽  
pp. 469-475 ◽  
Author(s):  
R. W. M. Van Deursen ◽  
M. M. Sanchez ◽  
J. A. Derr ◽  
M. B. Becker ◽  
J. S. Ulbrecht ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0183973 ◽  
Author(s):  
Amit Goel ◽  
Channabasappa Shivaprasad ◽  
Anish Kolly ◽  
Vijaya Sarathi H. A. ◽  
Sridevi Atluri

Author(s):  
Jong Young Lee ◽  
Dong Hoon Shin ◽  
Seung Hoon Lee ◽  
Moo Sik Lee ◽  
Suk Kwan Suh ◽  
...  

2019 ◽  
Vol 19 (2) ◽  
pp. 120-124 ◽  
Author(s):  
Arun G. Maiya ◽  
Anche Parameshwar ◽  
Manjunath Hande ◽  
Vinayak Nandalike

Foot ulcers, infections, and deformity are some of the major sources of mortality and morbidity among the diabetic population. The relationship between glycated hemoglobin (HbA1c) and diabetic peripheral neuropathy (DPN) has been well established. There is a dearth of literature on the relationship between vibration perception threshold (VPT) and HbA1c values. So, the objective of the study was to determine the strength of linear relationship between HbA1c levels and vibration perception threshold in DPN. This cross-sectional study was conducted at Kasturba Hospital, Manipal, and diabetic foot screening camps held at various parts of Udupi district. Ethical approval was obtained from the Institutional Ethics Committee, Kasturba Hospital, Manipal (IEC:281/2017). A total of 534 participants ranging from 30 to 70 years of age and were diagnosed with type 2 diabetes mellitus on medications were included in the study. Neuropathy assessment consisting of monofilament and vibration perception threshold was done using Neurotouch beta version (Yostra Labs, Bengaluru, India). HbA1c measurement was done using turbidimetric inhibition immunoassay technique (Roche Diagnostics, Mannheim, Germany). Pearson correlation coefficient showed a moderate to good correlation between HbA1c and VPT ( r = .0.753, P < .001). Linear regression result has shown a significant relationship of VPT with HbA1c (4.033 [95% confidence interval = 3.67-4.39]). The present study has concluded that there is strong relationship between HbA1c values and VPT and could be a predictor for complications in the foot following DPN.


Sign in / Sign up

Export Citation Format

Share Document