A two-stage analysis of the influences of employee alignment on effecting business–IT alignment

2012 ◽  
Vol 53 (3) ◽  
pp. 490-498 ◽  
Author(s):  
T.C. Wong ◽  
Shing-Chung Ngan ◽  
Felix T.S. Chan ◽  
Alain Yee-Loong Chong
Keyword(s):  
Two Stage ◽  
It Alignment ◽  
Employee Alignment ◽  
Business It Alignment ◽  
Stage Analysis

scholarly journals A coevolutionary framework of business-IT alignment via the lens of enterprise architecture

2020 ◽  
Vol 31 (5) ◽  
pp. 983-995
Author(s):  
Lin Menglong ◽  
Yi Shuanghui ◽  
Zhang Mengmeng ◽  
Chen Tao ◽  
Chen Honghui ◽  
...  
Keyword(s):  
Enterprise Architecture ◽  
It Alignment ◽  
Business It Alignment

Pharmacokinetics of Propofol after a Single Dose in Children Aged 1–3 Years with Minor Burns

1996 ◽  
Vol 84 (3) ◽  
pp. 526-532 ◽  
Author(s):  
I. Murat ◽  
V. Billard ◽  
J. Vernois ◽  
M. Zaouter ◽  
P. Marsol ◽  
...  
Keyword(s):  
Single Dose ◽  
Surface Area ◽  
Total Body Surface Area ◽  
Central Compartment ◽  
Pharmacokinetic Parameters ◽  
Systemic Clearance ◽  
Older Children ◽  
Noncompartmental Analysis ◽  
Two Stage ◽  
Stage Analysis

Background No complete pharmacokinetic profile of propofol is yet available in children younger than 3 yr, whereas clinical studies have demonstrated that both induction and maintenance doses of propofol are increased with respect to body weight in this age group compared to older children and adults. This study was therefore undertaken to determine the pharmacokinetics of propofol after administration of a single dose in aged children 1-3 yr requiring anesthesia for dressing change. Methods This study was performed in 12 children admitted to the burn unit and in whom burn surface area was less than or equal to 12% of total body surface area. Exclusion criteria were: unstable hemodynamic condition, inappropriate fluid loading, associated pulmonary injury, or burn injury older than 2 days. Propofol (4 mg.kg(-1))plus fentanyl (2.5 microg.kg(-1)) was administered while the children were bathed and the burn area cleaned during which the children breathed spontaneously a mixture of oxygen and nitrous oxide (50:50). Venous blood samples of 300 microl were obtained at 5, 15, 30, 60, 90, and 120 min, and 3, 4, 8, and 12 thereafter injection; an earlier sample was obtained from 8 of 12 children. The blood concentration curves obtained for individual children were analyzed by three different methods: noncompartmental analysis, mixed effects population model, and standard two-stage analysis. Results Using noncompartmental analysis, total clearance of propofol (+/-SD) was 0.053+/-0.013l.kg(-1).min(-1), volume of distribution at steady state9.5 +/- 3.7l.kg(-1),and residence time 188 +/- 85 min. Propofol pharmacokinetics were best described by a weight-proportional three-compartmental model in both population and two-stage analysis. Estimated and derived pharmacokinetic parameters were similar using these two pharmacokinetic approaches. Results of population versus two-stage analysis are as follow: systemic clearance 0.049 versus 0.048 l.kg(-).min(-1), volume of central compartment 1.03 versus 0.95 l.kg(-1), volume of steady state 8.09 versus 8.17 l.kg(-1). Conclusions The volume of the central compartment and the systemic clearance were both greater than all values reported in older children and adults. This is consistent with the increased propofol requirements for both induction and maintenance of anesthesia in children 1-3 yr. (Key words: Anesthesia: pediatric. Pharmacokinetics: propofol.)

Business/IT Alignment

2019 ◽  
pp. 75-90
Author(s):  
Steven De Haes ◽  
Wim Van Grembergen ◽  
Anant Joshi ◽  
Tim Huygh
Keyword(s):  
It Alignment ◽  
Business It Alignment

Business-IT Alignment Literature Review

2018 ◽  
Vol 31 (3) ◽  
pp. 34-53 ◽  
Author(s):  
Yu Jia ◽  
Nianxin Wang ◽  
Shilun Ge
Keyword(s):  
Citation Analysis ◽  
Knowledge Flows ◽  
Intellectual Structure ◽  
Future Research ◽  
Research Directions ◽  
It Alignment ◽  
Research Themes ◽  
Future Research Directions ◽  
Business It Alignment ◽  
New Perspective

The purpose of this article is to portray the knowledge evolution paths of business-IT alignment (BITA) research and identify a set of important papers in the development of BITA, and elucidate the intellectual structure of this field. This study collected 309 papers published during the period 1983-2015 from the Web of Science (WOS) database. Using a variety of bibliometric and visualization analytic techniques such as citation analysis, co-citation analysis and main path analysis, this article (1) delineates the significant knowledge flows of BITA research and identifies 15 important papers in this field; (2) graphically maps the influential countries, institutions, and journals of BITA research; (3) identifies four major research themes: BITA model, measurement, antecedents, and dynamics, and visualizing the relationships among them. Based on these findings, recommendations for the future research directions have suggested. This article provides IT practitioners, executives, and scholars with a new perspective to get a better understanding of BITA.

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