Genetic analysis of ionizing radiation-induced mutagenesis in Saccharomyces cerevisiae reveals TransLesion Synthesis (TLS) independent of PCNA K164 SUMOylation and ubiquitination

DNA Repair ◽  
2006 ◽  
Vol 5 (12) ◽  
pp. 1475-1488 ◽  
Author(s):  
Clark C. Chen ◽  
Akira Motegi ◽  
Yuko Hasegawa ◽  
Kyungjae Myung ◽  
Richard Kolodner ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Ionizing Radiation ◽  
Genetic Analysis ◽  
Translesion Synthesis ◽  
Radiation Induced ◽  
Induced Mutagenesis

scholarly journals Recovery of a low mutant frequency after ionizing radiation-induced mutagenesis during spermatogenesis

2008 ◽  
Vol 654 (2) ◽  
pp. 150-157 ◽  
Author(s):  
Guogang Xu ◽  
Gabriel W. Intano ◽  
John R. McCarrey ◽  
Ronald B. Walter ◽  
C. Alex McMahan ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Radiation Induced ◽  
Induced Mutagenesis ◽  
Mutant Frequency

scholarly journals GENETIC CONTROL OF RADIATION SENSITIVITY IN SCHIZOSACCHAROMYCES POMBE

Genetics ◽  
1975 ◽  
Vol 79 (4) ◽  
pp. 573-582
Author(s):  
A Nasim ◽  
B P Smith
Keyword(s):  
Ionizing Radiation ◽  
Genetic Analysis ◽  
Schizosaccharomyces Pombe ◽  
Genetic Control ◽  
Single Gene ◽  
Radiation Sensitivity ◽  
Cellular Repair ◽  
Repair Mechanisms ◽  
Radiation Induced

ABSTRACT Genetic analysis of a large number of radiation-sensitive mutants of S. pombe, isolated in different laboratories, showed that these isolates represent 22 non-allelic loci. The mutants were shown to fall into three distinct classes concerning response to UV and ionizing radiation, including two mutants which are primarily sensitive to ionizing radiation but not to UV. Single-gene mutants were crossed to obtain supersensitive double mutants. Such double mutants showed a marked increase in sensitivity to a variety of inactivating agents as compared to the parental strains. The isolation of three classes of radiation-sensitive mutants and the construction of double mutants implies the presence of multiple pathways in S. pombe for repair of radiation-induced damage. The bearing of these data on cellular repair mechanisms in eukaryotes is discussed.

Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells

2007 ◽  
Vol 250 (1) ◽  
pp. 63-73 ◽  
Author(s):  
Ying Zhang ◽  
Junqing Zhou ◽  
Xiaofan Cao ◽  
Qinming Zhang ◽  
Chang U.K. Lim ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Human Cells ◽  
Radiation Induced ◽  
Induced Mutagenesis ◽  
Partial Deficiency

scholarly journals A Shuttle Vector System for Studying Ionizing Radiation-Induced Mutagenesis in Mammalian Cells.

1993 ◽  
Vol 34 (2) ◽  
pp. 148-156
Author(s):  
CHIDORI MURAISO ◽  
JOHN S. MUDGETT ◽  
HIROMICHI MATSUDAIRA ◽  
GARY F. STRNISTE
Keyword(s):  
Ionizing Radiation ◽  
Mammalian Cells ◽  
Shuttle Vector ◽  
Vector System ◽  
Radiation Induced ◽  
Induced Mutagenesis

scholarly journals Enhanced fungicide resistance inIsaria fumosoroseafollowing ionizing radiation-induced mutagenesis

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Shinobu Shinohara ◽  
Yuyun Fitriana ◽  
Katsuya Satoh ◽  
Issay Narumi ◽  
Tsutomu Saito
Keyword(s):  
Ionizing Radiation ◽  
Fungicide Resistance ◽  
Radiation Induced ◽  
Induced Mutagenesis
Sign in / Sign up

Export Citation Format

Share Document