scholarly journals Long-term outcome of pediatric-onset Crohn’s disease: A population-based cohort study

2019 ◽  
Vol 51 (4) ◽  
pp. 496-502 ◽  
Author(s):  
Mathurin Fumery ◽  
Benjamin Pariente ◽  
Helene Sarter ◽  
Guillaume Savoye ◽  
Claire Spyckerelle ◽  
...  
Keyword(s):  
Cohort Study ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Population Based ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Pediatric Onset

scholarly journals P458 Long-term outcome of Crohn’s disease complicated by upper gastrointestinal stricture: A GETAID cohort study

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S336-S336
Author(s):  
T Lambin ◽  
A Amiot ◽  
J M Gornet ◽  
P Seksik ◽  
D Laharie ◽  
...  
Keyword(s):  
Cohort Study ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Upper Gastrointestinal

scholarly journals P137 Long-term outcome of paediatric-onset Crohn's disease: A population-based study

2012 ◽  
Vol 6 ◽  
pp. S64 ◽  
Author(s):  
A. Peneau ◽  
J. Salleron ◽  
M. Fumery ◽  
G. Savoye ◽  
E. Lerebours ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Population Based ◽  
Term Outcome ◽  
Population Based Study ◽  
Long Term Outcome

103 Long-Term Outcome of Paediatric-Onset Crohn's Disease: A Population-Based Study

2012 ◽  
Vol 142 (5) ◽  
pp. S-25 ◽  
Author(s):  
Anaïs Peneau ◽  
Julia Salleron ◽  
Mathurin Fumery ◽  
Guillaume Savoye ◽  
Eric Lerebours ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Population Based ◽  
Term Outcome ◽  
Population Based Study ◽  
Long Term Outcome

Mo1785 - Long-Term Outcome of Crohn's Disease Complicated by Upper Gastrointestinal Stricture: A Getaid Cohort Study

2018 ◽  
Vol 154 (6) ◽  
pp. S-801
Author(s):  
Thomas Lambin ◽  
Aurélien Amiot ◽  
Jean-Marc Gornet ◽  
Philippe Seksik ◽  
David Laharie ◽  
...  
Keyword(s):  
Cohort Study ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Upper Gastrointestinal

scholarly journals Early Initiation of Anti-TNF is Associated with Favourable Long-term Outcome in Crohn’s Disease: 10-Year-Follow-up Data from the Swiss IBD Cohort Study

2019 ◽  
Vol 13 (10) ◽  
pp. 1292-1301 ◽  
Author(s):  
Roy Frei ◽  
Nicolas Fournier ◽  
Jonas Zeitz ◽  
Michael Scharl ◽  
Bernhard Morell ◽  
...  
Keyword(s):  
Cohort Study ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Rank Test ◽  
Optimal Timing ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Medical Visits

Abstract Background and Aims The optimal timing of treatment escalation in Crohn’s disease [CD] remains a challenging issue, and very little is known about its long-term development following early versus late administration of anti-TNF antibodies. The long-term outcome of Swiss CD patients was comparatively assessed in an up to 10-year follow-up, using patients participating in the Swiss Inflammatory Bowel Disease Cohort Study [SIBDCS]. Methods Prospectively collected SIBDCS patient data, including disease history, baseline characteristics at enrolment, and course of disease, were analysed in patients with early versus late [<24 versus ≥24 months after diagnosis] and no anti-TNF treatment. Results A reduced risk of developing bowel stenosis was found in patients who received early anti-TNF treatment. This association was seen in patients overall and also in the subgroups of CD patients without pre-existing complications [Log-rank test: p < 0.001]. Furthermore, osteoporosis and anaemia were observed significantly less frequently in patients who received early anti-TNF treatment, compared with either patients who received treatment late [p < 0.001 and p = 0.046, respectively] or were never [p < 0.001 for both] treated with anti-TNF antibodies. Patients with early anti-TNF administration sought medical consultations significantly less often, including gastroenterologists in private practice [p = 0.017], ambulatory [outpatient] hospital visits [p = 0.038], and a composite of any medical visits [p = 0.001]. The percentage of patients unable to work was lowest for early-anti-TNF–treated patients, in comparison with patients who were treated late or never [3.6% vs 8.8% vs 3.7%, p = 0.016]. Conclusions In CD patients within the SIBDCS, early anti-TNF administration was found to be associated with several indicators of a more favourable long-term outcome.

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