Hepatocellular carcinoma recurrence rate in HCV infected patients treated with direct antiviral agents. A single center experience

2017 ◽  
Vol 49 (1) ◽  
pp. e45-e46
Author(s):  
R. Granata ◽  
G.G. Di Costanzo ◽  
M. Sanduzzi Zamparelli ◽  
M. Guarino ◽  
G. Cordone ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Recurrence Rate ◽  
Antiviral Agents ◽  
Single Center ◽  
Single Center Experience ◽  
Direct Antiviral Agents ◽  
Hepatocellular Carcinoma Recurrence

scholarly journals Hepatocellular Carcinoma Recurrence in HCV Patients Treated with Direct Antiviral Agents

Viruses ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 406 ◽  
Author(s):  
Marco Sanduzzi-Zamparelli ◽  
Loreto Boix ◽  
Cassia Leal ◽  
María Reig
Keyword(s):  
Hepatocellular Carcinoma ◽  
De Novo ◽  
Antiviral Agents ◽  
The Subject ◽  
Direct Antiviral Agents ◽  
Hepatocellular Carcinoma Recurrence ◽  
Underlying Mechanisms ◽  
Almost All ◽  
The Impact ◽  
Hcc Recurrence

The risk of hepatocellular carcinoma recurrence is universal regardless of the treatment modality applied, and secondary prevention is still an unmet issue even though the elimination of hepatitis C (HCV) with direct antiviral agents (DAAs) was expected to be one of the new options. Unfortunately, the impact of DAAs on hepatocellular carcinoma (HCC) development (de novo and recurrence) is still controversial. Since the first publication on the subject in 2016, almost all groups worldwide have carried out research in this field with hundreds of publications now available. This revision is focused on the impact of DAAs on HCC recurrence and aims to discuss the potential underlying mechanisms and host factors pointing out the time association phenomenon between DAA treatment and HCC recurrence. Moreover, we comment on the methodological issues that could affect the different interpretations of the published results. In conclusion, this is an area of research with potential in the understanding of the impact of factors not previously considered, and may also help change hepatocarcinogenesis tenets, such as the belief that the elimination of HCV should be used as a second prevention treatment.

Liver transplantation for hepatocellular carcinoma: A single center experience

2004 ◽  
Vol 42 (05) ◽  
Author(s):  
V Stadlbauer ◽  
S Schaffellner ◽  
D Kniepeiss ◽  
E Jakoby ◽  
F Iberer ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Single Center ◽  
Single Center Experience
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