Positivity rates and performances of immunochemical faecal occult blood tests at different cut-off levels within a colorectal cancer screening programme

2012 ◽  
Vol 44 (8) ◽  
pp. 700-704 ◽  
Author(s):  
Jean Faivre ◽  
Vincent Dancourt ◽  
Sylvain Manfredi ◽  
Bernard Denis ◽  
Gérard Durand ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Screening ◽  
Colorectal Cancer Screening ◽  
Screening Programme ◽  
Occult Blood ◽  
Faecal Occult Blood ◽  
Blood Tests ◽  
Faecal Occult ◽  
Cancer Screening Programme

scholarly journals Results of the Czech National Colorectal Cancer Screening Programme – Faecal Occult Blood Tests

2014 ◽  
Vol 27 (Suppl 2) ◽  
pp. 2S87-2S97
Author(s):  
Bohumil Seifert ◽  
Ondřej Májek ◽  
Miroslav Zavoral ◽  
Norbert Král ◽  
Štěpán Suchánek ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Screening ◽  
Colorectal Cancer Screening ◽  
Screening Programme ◽  
Occult Blood ◽  
Faecal Occult Blood ◽  
Blood Tests ◽  
Faecal Occult ◽  
Cancer Screening Programme

scholarly journals Implementation of Failure Mode and Effects Analysis to the specimens flow in a population-based colorectal cancer screening programme using immunochemical faecal occult blood tests: a quality improvement project in the Milan colorectal cancer screening programme

2018 ◽  
Vol 7 (1) ◽  
pp. e000299 ◽  
Author(s):  
Silvia Deandrea ◽  
Enrica Tidone ◽  
Aldo Bellini ◽  
Luigi Bisanti ◽  
Nico Gerardo Leonardo ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Screening ◽  
Colorectal Cancer Screening ◽  
Failure Modes ◽  
Screening Programme ◽  
Occult Blood ◽  
Faecal Occult Blood ◽  
Faecal Occult ◽  
Cancer Screening Programme ◽  
Corrective Actions

BackgroundA multidisciplinary working group applied the Healthcare Failure Mode and Effects Analysis (HFMEA) approach to the flow of kits and specimens for the first-level test of a colorectal cancer screening programme using immunochemical faecal occult blood tests.MethodsHFMEA comprised four steps: (1) identification and mapping of the process steps (subprocesses); (2) analysis of failure modes and calculation of the risk priority numbers (RPNs); (3) identification of corrective actions; and (4) follow-up and evaluation of corrective actions.ResultsThe team identified 9 main failure modes, 12 effects and 34 associated causes. RPN scores ranged from 2 to 96. Failure modes within the first five positions in the ranking list ordered by RPN concerned: ‘degraded haemoglobin in the specimen’, ‘mixed-up kits’ and ‘anonymous specimen’. All of these could lead to false-negative results and/or subjects with positive tests not being recalled for assessment. The team planned corrective actions for those failure modes. As a result, the follow-up of corrective actions showed a significant decrease in the proportion of anonymous kits from 11.6 to 4.8 per 1000 (relative reduction of 59%). The HFMEA exercise led to a reduction in: missed positive tests; missed cancer and high-risk adenomas; complaints about the communication of test results to a person who never did the test; and false-negative results due either to haemoglobin degradation or an expired sampling tube.ConclusionsHFMEA is a useful tool for reducing errors in colorectal cancer screening programmes using faecal occult blood tests and is characterised by a straightforward interpretation of results and ease of communication to healthcare managers and decision makers.

713 False Negative Immunochemical Faecal Occult Blood Tests Due to Delayed Sample Return in Colorectal Cancer Screening.

2009 ◽  
Vol 136 (5) ◽  
pp. A-113
Author(s):  
Leo G. van Rossum ◽  
Anne Floortje van Rijn ◽  
Martijn G. van Oijen ◽  
Paul Fockens ◽  
Robert J. Laheij ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Screening ◽  
Colorectal Cancer Screening ◽  
False Negative ◽  
Occult Blood ◽  
Sample Return ◽  
Faecal Occult Blood ◽  
Blood Tests ◽  
Faecal Occult
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