The quality of life in patients with chronic pancreatitis evaluated using the SF-12 questionnaire: A comparative study with the SF-36 questionnaire

Author(s):  
R PEZZILLI ◽  
A MORSELLILABATE ◽  
L FRULLONI ◽  
G CAVESTRO ◽  
B FERRI ◽  
...  
Pancreas ◽  
2005 ◽  
Vol 31 (4) ◽  
pp. 463
Author(s):  
R Pezzilli ◽  
A M Morselli-Labate ◽  
L Fantini ◽  
L Frulloni ◽  
G M Cavestro ◽  
...  

Author(s):  
A. V. Okhlobystin ◽  
M. A. Tatarkina ◽  
O. Z. Okhlobystina ◽  
S. A. Budzinskiy ◽  
P. V. Pavlov ◽  
...  

Aim. To study the contribution of biliary sludge (BS) to the development of chronic pancreatitis in patients with gallbladder sludge and verified chronic pancreatitis; to evaluate the clinical efficacy and safety of hymecromone therapy according to clinical and laboratory signs, as well as dynamics of gallbladder size and contractility.Materials and methods. An open single-centre clinical trial included 30 patients with chronic pancreatitis (CP), which was diagnosed according to the Cambridge criteria. All patients received hymocromone (Odeston®) 400 mg tid for 3 weeks. An analysis of the efficacy and safety of the studied drug was performed on the 21st day of treatment based on the results of laboratory tests, abdominal ultrasound, cholecystography and endosonography of the pancreatobiliary zone, quality-of-life assessment according to the SF-36 questionnaire, the frequency and severity of adverse effects (AE).Results. CP signs were found in 6.3 % of patients with gallbladder BS. CP was significantly more frequent in patients with putty-like bile (33.3 %, χ2 = 38.21, p < 0.00001). The area of the major duodenal papilla (MDP) was below normal in 78% of patients. According to factor analysis, monotherapy with hymocromone resulted in a decrease in abdominal pain, nausea, heaviness in the abdomen and bloating. By the end of the therapy, the quality of life according to the “BP” bodily pain scale of the SF-36 questionnaire significantly increased.Conclusions. Biliary sludge (including undiagnosed forms during routine examination) was found to be a factor in the development of CP. The medical correction of biliary disorders in CP should include selective antispasmodics. Hymecromone therapy demonstrates a good level of tolerability and safety, normalizes the motor function of the biliary tract and sphincter tone over a short period of time, and relieves CP symptoms.


2021 ◽  
Vol 63 (1) ◽  
pp. 33-37
Author(s):  
Liliya S. Babinets ◽  
Halyna M. Sasyk ◽  
Iryna M. Halabitska ◽  
Victoria R. Mykuliak

Introduction: An important place in the formation of the rehabilitation program is occupied by non-drug methods, such as physiotherapy, reflexology, spa treatment, the use of which improves the effectiveness of correction of complications, reduces drug load, allows to achieve sustainable compensation for diabetes and chronic pancreatitis (CP), and also improves life quality suffering from such comorbidity. Aim: to investigate the effectiveness of the use of acupuncture in the complex rehabilitation of patients with type 2 diabetes in combination with chronic pancreatitis based on an assessment of the quality of life (QOL) and clinical parameters. Material and Methods: 60 patients with type 2 diabetes in combination with CP were examined and divided into 2 groups. The average age of the patients was (52.86±0.83) years. Control group – 15 healthy persons. To evaluate QOL, a questionnaire was interviewed using the SF-36 questionnaire in treatment dynamics. All patients with type 2 diabetes in combination with CP received adequate conventional therapy. In addition to the treatment, the patients of group II received the acupuncture course according to the methodology, which was formed on the basis of the experience of the Kyiv School of reflexology (EL Macheret et al.) and the Beijing School (Kong Lin). Results: Faecal α-elastase levels increased by 14.9% in group 1, by 25.6% in group 2, blood glucose decreased by 9.2% in group 1 and by 19.5% in group 2, HbA1c level – by 4.9% in Group 1 and by 12.2% in Group 2, changes in coprogram parameters in points – by 24.5% in Group 1 and by 55.2% in Group 2. According to the SF-36 scales, there was a positive dynamics of quality of life in patients of both groups. In group 2, there was a more significant positive trend in the total indicator of mental status (increased by 17.75% (p <0.001) versus 8.71% (p <0.005) in the group 1, respectively) and physical status (increased by 2.59% ( p <0.05) versus 7.19% (p <0.05)). Conclusions: Improved exocrine and endocrine functions of the pancreas, as well as improved quality of life in patients treated with a course of acupuncture increase the efficiency of complex rehabilitation of patients with type 2 diabetes in combination with CP was found.


2019 ◽  
Vol 1 (6) ◽  
pp. 56-60
Author(s):  
N. B. Gubergrits ◽  
E. A. Krylova ◽  
E. Yu. Plotnikova

In 72 patients with chronic pancreatitis were studied quality of life indicators using a common questionnaire the SF-36 (Short Form-36, Healt Status Survey) in the dynamics of treatment. It was established that the disease affects the quality of life of patients, affecting all levels of life:physical, emotional, role, psychological, social functioning. After treatment, the quality of life of patients significantly improved both indicators of physical and social health of patients increased the overall tone and physical activity during the day, improves sleep at night.


Author(s):  
M. V. Palykhata ◽  
L. S. Babinets ◽  
O. V. Pronyuk

Вивчення якості життя (ЯЖ) у всьому світі є однією з актуальних проблем у медицині. Опитувальники є надійним і дійсним інструментом для вимірювання ЯЖ з точки зору пацієнта. Шкала часто використовуються з упевненістю у пацієнтів з хронічними захворюваннями, що потребують довготривалої терапії. У пацієнтів із хронічним панкреатитом (ХП) і супутньою анемією частіше зустрічаються супутні когнітивні порушення у молодих жінок, більший ризик летальності та госпіталізацій у дорослих і особливо у пацієнтів літнього віку, порушення терморегуляції, дисфункція імунної системи, шлунково-кишкові розлади, інфекція Helicobacter pylori, які ще більше знижують ЯЖ. Наше дослідження ЯЖ у пацієнтів із ХП і ХП із супутнім анемічним синдромом за допомогою опитувальників SF-36 і GSRS, продемонстрували значно нижчий рівень ЯЖ у пацієнтів із анемією. Це свідчить про об’єктивну обтяжувальну роль супутньої анемії на перебіг основного захворювання.


2021 ◽  
Vol 55 (3) ◽  
pp. 191-198
Author(s):  
V.G. Yareshko ◽  
Iu.O. Mikheiev ◽  
O.F. Shpylenko ◽  
O.M. Babii

Background. The majority of studies on the surgical treatment of chronic pancreatitis (CP) compare treatment outcomes by the type of the procedure. However, some studies, especially systematic reviews and meta-analyses, indicate the equality of different surgeries by their long-term results. During last 5–9 years, several studies showed advantages of early surgery in chronic pancreatitis, within three years after symptoms onset. Objective: to analyze the short- and long-term results of surgical treatment for chronic pancreatitis regarding timing and, accordingly, the neglect of the disease. Materials and methods. Retrospective analysis of data of 147 patients from 2001 to 2020, the main intervention was surgery aimed at the main manifestations of CP, such as pancreatic ductal and/or parenchymal hypertension. Patients who suffered from CP symptoms 3 years or more were included in the control group (late surgery), and those who noted symptoms of CP for less than 3 years were included in the study group (early surgery). All patients completed the EORTC QLQ-30, SF-36 questionnaires, as well as the questionnaire developed by the study authors, via telephone or mail, or during the visit. Results. According to all scales of the SF-36 questionnaire, except for Physical functioning, the group of early surgery prevails over the group of late surgery. The early surgery group had the best average scores on all functional scales of the EORTC QLQ-30 questionnaire compared to the late surgery group, except for the Cognitive functioning. Of the symptomatic scales, the early surgery group had the best averages on Pain and Diarrhea. The average Health/Quality of life scale was significantly better in the early surgery group. Conclusions. The quality of life, pain control, pancreatic function in patients operated within 3 years from the onset of CP symptoms were better compared to those with longer disease duration, with the same short-term results. The duration of the disease is a major factor for the success of surgical treatment of chronic pancreatitis in terms of long-term results. The early surgery is effective approach to obtain better long-term outcomes in chronic pancreatitis.


2021 ◽  
Vol 15 (3) ◽  
pp. 69-74
Author(s):  
V. I. Panikar ◽  
E. I. Korshun ◽  
S. G. Anikin ◽  
O. V. Bochko ◽  
E. A. Voronina ◽  
...  

Objective: to develop a personalized rehabilitation program for improving age-related resilience (AR), antioxidant status (AOS), the quality of life and reducing pain in elderly patients with osteoarthritis (OA).Patients and methods. The program consisted of two parts. In the first part, we conducted a comparative study to assess the AR (Mahnach test), geriatric status, and AOS (amperometric flow-injection analysis) in 181 subjects in total, with coxarthrosis (n=92) and without it (n=89). The average age of patients in two groups was comparable: 72.1±1.1 and 71.9±1.1 years. Using factor analysis, we developed the personalized rehabilitation program based on the obtained data. The effectiveness of the program was evaluated in the second part of our work. We conducted an additional comparative study of changes in AR, AOS, severity of joint pain (by visual analogue scale, VAS) and quality of life (according to SF-36 questionnaire) in patients with coxarthrosis (n=114).Results and discussion. Patients with coxarthrosis had significantly lower level of AR, total antioxidant, and antiradical activity, and a higher content of Schiff bases as compared to subjects without coxarthrosis (p<0.05). The program of rehabilitation, which included a course of treatment with Chondroquard, significantly improved AR, AOS, quality of life and reduced hip pain compared to the standard OA therapy (p<0.05).Conclusion. The personalized rehabilitation program has a complex positive effect on pain, quality of life, AR and AOS in elderly patients with OA.


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