scholarly journals Data on CUX1 isoforms in idiopathic pulmonary fibrosis lung and systemic sclerosis skin tissue sections

Data in Brief ◽  
2016 ◽  
Vol 8 ◽  
pp. 1377-1380
Author(s):  
Tetsurou Ikeda ◽  
Maria Fragiadaki ◽  
Xu Shi-wen ◽  
Markella Ponticos ◽  
Korsa Khan ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Skin Tissue ◽  
Tissue Sections ◽  
Idiopathic Pulmonary Fibrosis Lung

Idiopathic Pulmonary Fibrosis and Pulmonary Fibrosis in Diffuse Systemic Sclerosis: Two Fibroses with Different Prognoses

Respiration ◽  
1997 ◽  
Vol 64 (1) ◽  
pp. 81-85 ◽  
Author(s):  
Spyros A. Papiris ◽  
Panayiotis G. Vlachoyiannopoulos ◽  
Maria A. Maniati ◽  
Konstantinos X. Karakostas ◽  
Stavros H. Constantopoulos ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Diffuse Systemic Sclerosis

scholarly journals Immunohistochemical and morphometric evaluation of COX 1 and COX-2 in the remodeled lung in idiopathic pulmonary fibrosis and systemic sclerosis

2013 ◽  
Vol 39 (6) ◽  
pp. 692-700 ◽  
Author(s):  
Edwin Roger Parra ◽  
Flavia Lin ◽  
Vanessa Martins ◽  
Maristela Peres Rangel ◽  
Vera Luiza Capelozzi
Keyword(s):  
Systemic Sclerosis ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Interstitial Pneumonia ◽  
Lung Tissue ◽  
Alveolar Volume ◽  
Risk Of Death ◽  
Cox 2 ◽  
Alveolar Septa ◽  
Cox 1

OBJECTIVE: To study the expression of COX-1 and COX-2 in the remodeled lung in systemic sclerosis (SSc) and idiopathic pulmonary fibrosis (IPF) patients, correlating that expression with patient survival.METHODS: We examined open lung biopsy specimens from 24 SSc patients and 30 IPF patients, using normal lung tissue as a control. The histological patterns included fibrotic nonspecific interstitial pneumonia (NSIP) in SSc patients and usual interstitial pneumonia (UIP) in IPF patients. We used immunohistochemistry and histomorphometry to evaluate the expression of COX-1 and COX-2 in alveolar septa, vessels, and bronchioles. We then correlated that expression with pulmonary function test results and evaluated its impact on patient survival.RESULTS: The expression of COX-1 and COX-2 in alveolar septa was significantly higher in IPF-UIP and SSc-NSIP lung tissue than in the control tissue. No difference was found between IPF-UIP and SSc-NSIP tissue regarding COX-1 and COX-2 expression. Multivariate analysis based on the Cox regression model showed that the factors associated with a low risk of death were younger age, high DLCO/alveolar volume, IPF, and high COX-1 expression in alveolar septa, whereas those associated with a high risk of death were advanced age, low DLCO/alveolar volume, SSc (with NSIP), and low COX-1 expression in alveolar septa.CONCLUSIONS: Our findings suggest that strategies aimed at preventing low COX-1 synthesis will have a greater impact on SSc, whereas those aimed at preventing high COX-2 synthesis will have a greater impact on IPF. However, prospective randomized clinical trials are needed in order to confirm that.

scholarly journals Screening for Helicobacter pylori in Idiopathic Pulmonary Fibrosis Lung Biopsies

Respiration ◽  
2015 ◽  
Vol 91 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Michael Kreuter ◽  
Detlef Kirsten ◽  
Thomas Bahmer ◽  
Roland Penzel ◽  
Martin Claussen ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Idiopathic Pulmonary Fibrosis Lung ◽  
Lung Biopsies

CT Features of Lung Disease in Patients with Systemic Sclerosis: Comparison with Idiopathic Pulmonary Fibrosis and Nonspecific Interstitial Pneumonia

Radiology ◽  
2004 ◽  
Vol 232 (2) ◽  
pp. 560-567 ◽  
Author(s):  
Sujal R. Desai ◽  
Srihari Veeraraghavan ◽  
David M. Hansell ◽  
Ageliki Nikolakopolou ◽  
Nicole S. L. Goh ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lung Disease ◽  
Interstitial Pneumonia ◽  
Nonspecific Interstitial Pneumonia ◽  
Ct Features
Sign in / Sign up

Export Citation Format

Share Document