scholarly journals Dataset of red light induced pupil constriction superimposed on post-illumination pupil response

Data in Brief ◽  
2016 ◽  
Vol 8 ◽  
pp. 1300-1302
Author(s):  
Shaobo Lei ◽  
Herbert C. Goltz ◽  
Jaime C. Sklar ◽  
Agnes M.F. Wong
Keyword(s):  
Red Light ◽  
Pupil Response ◽  
Pupil Constriction

scholarly journals Pulses of melanopsin-directed contrast produce highly reproducible pupilresponses that are insensitive to a change in background radiance

2018 ◽  
Author(s):  
Harrison McAdams ◽  
Aleksandra Sasha Igdalova ◽  
Manuel Spitschan ◽  
David H. Brainard ◽  
Geoffrey K. Aguirre
Keyword(s):  
Blue Light ◽  
Human Subjects ◽  
Clinical Pathology ◽  
Primary Interest ◽  
High Reproducibility ◽  
Pupil Response ◽  
Silent Substitution ◽  
Temporal Shape ◽  
Pupil Constriction ◽  
Average Pupil

AbstractPurposeTo measure the pupil response to pulses of melanopsin-directed contrast, and compare this response to those evoked by cone-directed contrast and spectrally-narrowband stimuli.Methods3-second unipolar pulses were used to elicit pupil responses in human subjects across 3 sessions. Thirty subjects were studied in Session 1, and most returned for Sessions 2 and 3. The stimuli of primary interest were “silent substitution” cone‐ and melanopsin-directed modulations. Red and blue narrowband pulses delivered using the post-illumination pupil response (PIPR) paradigm were also studied. Sessions 1 and 2 were identical, while Session 3 involved modulations around higher radiance backgrounds. The pupil responses were fit by a model whose parameters described response amplitude and temporal shape.ResultsGroup average pupil responses for all stimuli overlapped extensively across Sessions 1 and 2, indicating high reproducibility. Model fits indicate that the response to melanopsin-directed contrast is prolonged relative to that elicited by cone-directed contrast. The group average cone‐ and melanopsin-directed pupil responses from Session 3 were highly similar to those from Sessions 1 and 2, suggesting that these responses are insensitive to background radiance over the range studied. The increase in radiance enhanced persistent pupil constriction to blue light.ConclusionsThe group average pupil response to stimuli designed through silent substitution provides a reliable probe of the function of a melanopsin-mediated system in humans. As disruption of the melanopsin system may relate to clinical pathology, the reproducibility of response suggests that silent substitution pupillometry can test if melanopsin signals differ between clinical groups.

scholarly journals The absence of attenuating effect of red light exposure on pre-existing melanopsin-driven post-illumination pupil response

2016 ◽  
Vol 124 ◽  
pp. 59-65 ◽  
Author(s):  
Shaobo Lei ◽  
Herbert C. Goltz ◽  
Jaime C. Sklar ◽  
Agnes M.F. Wong
Keyword(s):  
Light Exposure ◽  
Red Light ◽  
Pupil Response

The effect of previous optic chiasm compression on the post-illumination pupil response in pituitary patients

2019 ◽  
Author(s):  
Tessel Boertien ◽  
Wisse van der Meijden ◽  
Adriaan Coumou ◽  
Madeleine Drent ◽  
Eus Van Someren ◽  
...  
Keyword(s):  
Optic Chiasm ◽  
Pupil Response

Postnatal growth rate and gonadal development in circadian tau mutant hamsters reared in constant dim red light

Reproduction ◽  
2000 ◽  
pp. 327-330 ◽  
Author(s):  
RJ Lucas ◽  
JA Stirland ◽  
YN Mohammad ◽  
AS Loudon
Keyword(s):  
Time Course ◽  
Red Light ◽  
Somatic Growth ◽  
Postnatal Growth ◽  
Gonadal Development ◽  
Testicular Development ◽  
Wild Type ◽  
Similar Time ◽  
Syrian Hamsters ◽  
Body Weights

The role of the circadian clock in the reproductive development of Syrian hamsters (Mesocricetus auratus was examined in wild type and circadian tau mutant hamsters reared from birth to 26 weeks of age under constant dim red light. Testis diameter and body weights were determined at weekly intervals in male hamsters from 4 weeks of age. In both genotypes, testicular development, subsequent regression and recrudescence exhibited a similar time course. The age at which animals displayed reproductive photosensitivity, as exhibited by testicular regression, was unrelated to circadian genotype (mean +/- SEM: 54 +/- 3 days for wild type and 59 +/- 5 days for tau mutants). In contrast, our studies revealed a significant impact of the mutation on somatic growth, such that tau mutants weighed 18% less than wild types at the end of the experiment. Our study reveals that the juvenile onset of reproductive photoperiodism in Syrian hamsters is not timed by the circadian system.

Inhibition of Various Steps in the Replication Cycle of Vesicular Stomatitis Virus Contributes to Its Photoinactivation by AlPcS4 or Pc4 and Red Light

1999 ◽  
Vol 69 (3) ◽  
pp. 353 ◽  
Author(s):  
Anne C. E. Moor ◽  
Angeline E. Wagenaars-van Gompel ◽  
Ralph C. A. Hermanns ◽  
Jannes van der Meulen ◽  
Jolanda Smit ◽  
...  
Keyword(s):  
Vesicular Stomatitis Virus ◽  
Red Light ◽  
Replication Cycle ◽  
Vesicular Stomatitis
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