scholarly journals A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration

2018 ◽  
Vol 46 (2) ◽  
pp. 135-143 ◽  
Author(s):  
Michael N. Wosczyna ◽  
Thomas A. Rando
Keyword(s):  
Stem Cell ◽  
Support Group ◽  
Muscle Regeneration ◽  
Cellular Responses ◽  
Muscle Stem Cell ◽  
Stem Cell Support ◽  
Cell Support

scholarly journals The CXCL12 Crossroads in Cancer Stem Cells and Their Niche

Cancers ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 469
Author(s):  
Juan Carlos López-Gil ◽  
Laura Martin-Hijano ◽  
Patrick C. Hermann ◽  
Bruno Sainz
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Tumor Microenvironment ◽  
Cancer Stem Cells ◽  
Crucial Role ◽  
Diverse Group ◽  
Hematopoietic Stem ◽  
Stem Cell Support ◽  
Cell Support ◽  
Tumor Entities

Cancer stem cells (CSCs) are defined as a subpopulation of “stem”-like cells within the tumor with unique characteristics that allow them to maintain tumor growth, escape standard anti-tumor therapies and drive subsequent repopulation of the tumor. This is the result of their intrinsic “stem”-like features and the strong driving influence of the CSC niche, a subcompartment within the tumor microenvironment that includes a diverse group of cells focused on maintaining and supporting the CSC. CXCL12 is a chemokine that plays a crucial role in hematopoietic stem cell support and has been extensively reported to be involved in several cancer-related processes. In this review, we will provide the latest evidence about the interactions between CSC niche-derived CXCL12 and its receptors—CXCR4 and CXCR7—present on CSC populations across different tumor entities. The interactions facilitated by CXCL12/CXCR4/CXCR7 axes seem to be strongly linked to CSC “stem”-like features, tumor progression, and metastasis promotion. Altogether, this suggests a role for CXCL12 and its receptors in the maintenance of CSCs and the components of their niche. Moreover, we will also provide an update of the therapeutic options being currently tested to disrupt the CXCL12 axes in order to target, directly or indirectly, the CSC subpopulation.

Acute Pseudo-Obstruction of the Small Intestine Following High-Dose Chemotherapy and Stem Cell Support

2003 ◽  
Vol 26 (4) ◽  
pp. 344-346 ◽  
Author(s):  
T. Bauernhofer ◽  
M. Eibl ◽  
F. Ploner ◽  
I. Kuss ◽  
J. Pfeifer ◽  
...  
Keyword(s):  
Small Intestine ◽  
Stem Cell ◽  
High Dose Chemotherapy ◽  
High Dose ◽  
Stem Cell Support ◽  
Cell Support

High-dose chemotherapy and stem-cell support in breast cancer

The Lancet ◽  
1998 ◽  
Vol 352 (9135) ◽  
pp. 1220
Author(s):  
Paolo Pedrazzoli ◽  
Gian Antonio Da Prada ◽  
Gioacchino Robustelli della Cuna
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
High Dose Chemotherapy ◽  
High Dose ◽  
Stem Cell Support ◽  
Cell Support

Angiogenetic Factors and Biochemical Markers of Bone Metabolism in POEMS Syndrome Treated with High-Dose Therapy and Autologous Stem Cell Support

2006 ◽  
Vol 7 (1) ◽  
pp. 73-76 ◽  
Author(s):  
Efstathios Kastritis ◽  
Evangelos Terpos ◽  
Athanasios Anagnostopoulos ◽  
Irini Xilouri ◽  
Meletios Athanasios Dimopoulos
Keyword(s):  
Stem Cell ◽  
Bone Metabolism ◽  
Biochemical Markers ◽  
Poems Syndrome ◽  
High Dose ◽  
High Dose Therapy ◽  
Stem Cell Support ◽  
Dose Therapy ◽  
Cell Support
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