Superoxide dismutase isoforms 1 and 2 in lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin treatment

2005 ◽  
Vol 154 (2) ◽  
pp. 217-225 ◽  
Author(s):  
Fábio Rogério ◽  
Simone A. Teixeira ◽  
Alexandre César Santos de Rezende ◽  
Rafael Cofiño de Sá ◽  
Luciano de Souza Queiroz ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Superoxide Dismutase ◽  
Sciatic Nerve ◽  
Lumbar Spinal Cord ◽  
Nerve Transection ◽  
Neonatal Rats ◽  
Melatonin Treatment ◽  
Sciatic Nerve Transection ◽  
Lumbar Spinal

mRNA and protein expression and activities of nitric oxide synthases in the lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin administration

2006 ◽  
Vol 407 (2) ◽  
pp. 182-187 ◽  
Author(s):  
Fábio Rogério ◽  
Simone Aparecida Teixeira ◽  
Hamilton Jordão Júnior ◽  
Carla Cristina Judice Maria ◽  
André Schwambach Vieira ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Spinal Cord ◽  
Sciatic Nerve ◽  
Lumbar Spinal Cord ◽  
Nerve Transection ◽  
Neonatal Rats ◽  
Sciatic Nerve Transection ◽  
Melatonin Administration ◽  
Mrna And Protein Expression ◽  
Lumbar Spinal

Neonatal sciatic nerve transection induces TUNEL labeling of neurons in the rat spinal cord and DRG

Neuroreport ◽  
1997 ◽  
Vol 8 (13) ◽  
pp. 2837-2840 ◽  
Author(s):  
A L. R. Oliveira ◽  
M Risling ◽  
M Deckner ◽  
T Lindholm ◽  
F Langone ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Sciatic Nerve ◽  
Nerve Transection ◽  
Rat Spinal Cord ◽  
Sciatic Nerve Transection

scholarly journals Effect of Sciatic Nerve Transection on acetylcholinesterase activity in spinal cord and skeletal muscles of the bullfrog Lithobates catesbeianus

2017 ◽  
Vol 78 (2) ◽  
pp. 217-223
Author(s):  
A. Kroth ◽  
V. Mackedanz ◽  
C. Matté ◽  
A. T. S. Wyse ◽  
M. F. M. Ribeiro ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Neuropathic Pain ◽  
Sciatic Nerve ◽  
Skeletal Muscles ◽  
Ache Activity ◽  
Clinical Symptoms ◽  
Phantom Limb ◽  
Nerve Transection ◽  
Sciatic Nerve Transection ◽  
Lithobates Catesbeianus

Abstract Sciatic nerve transection (SNT), a model for studying neuropathic pain, mimics the clinical symptoms of “phantom limb”, a pain condition that arises in humans after amputation or transverse spinal lesions. In some vertebrate tissues, this condition decreases acetylcholinesterase (AChE) activity, the enzyme responsible for fast hydrolysis of released acetylcholine in cholinergic synapses. In spinal cord of frog Rana pipiens, this enzyme’s activity was not significantly changed in the first days following ventral root transection, another model for studying neuropathic pain. An answerable question is whether SNT decreases AChE activity in spinal cord of frog Lithobates catesbeianus, a species that has been used as a model for studying SNT-induced neuropathic pain. Since each animal model has been created with a specific methodology, and the findings tend to vary widely with slight changes in the method used to induce pain, our study assessed AChE activity 3 and 10 days after complete SNT in lumbosacral spinal cord of adult male bullfrog Lithobates catesbeianus. Because there are time scale differences of motor endplate maturation in rat skeletal muscles, our study also measured the AChE activity in bullfrog tibial posticus (a postural muscle) and gastrocnemius (a typical skeletal muscle that is frequently used to study the motor system) muscles. AChE activity did not show significant changes 3 and 10 days following SNT in spinal cord. Also, no significant change occurred in AChE activity in tibial posticus and gastrocnemius muscles at day 3. However, a significant decrease was found at day 10, with reductions of 18% and 20% in tibial posticus and gastrocnemius, respectively. At present we cannot explain this change in AChE activity. While temporally different, the direction of the change was similar to that described for rats. This similarity indicates that bullfrog is a valid model for investigating AChE activity following SNT.

Synaptic targets of commissural interneurons in the lumbar spinal cord of neonatal rats

2003 ◽  
Vol 461 (4) ◽  
pp. 429-440 ◽  
Author(s):  
András Birinyi ◽  
Kornél Viszokay ◽  
Ildikó Wéber ◽  
Ole Kiehn ◽  
Miklós Antal
Keyword(s):  
Spinal Cord ◽  
Lumbar Spinal Cord ◽  
Neonatal Rats ◽  
Lumbar Spinal

Differential effects of pro-BDNF on sensory neurons after sciatic nerve transection in neonatal rats

2008 ◽  
Vol 27 (9) ◽  
pp. 2380-2390 ◽  
Author(s):  
Yong-jun Fan ◽  
Linda Lin-yan Wu ◽  
Hong-yun Li ◽  
Yan-Jiang Wang ◽  
Xin-Fu Zhou
Keyword(s):  
Sciatic Nerve ◽  
Sensory Neurons ◽  
Nerve Transection ◽  
Neonatal Rats ◽  
Sciatic Nerve Transection ◽  
Differential Effects
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