Hemorrhagic hydrocephalus (hhy): a novel mutation on mouse chromosome 12

2004 ◽  
Vol 152 (1) ◽  
pp. 69-72 ◽  
Author(s):  
Mitsuru Kuwamura ◽  
Asako Kinoshita ◽  
Masaaki Okumoto ◽  
Jyoji Yamate ◽  
Nobuko Mori
Keyword(s):  
Mouse Chromosome ◽  
Novel Mutation ◽  
Chromosome 12

Mouse Chromosome 12

1992 ◽  
Vol 3 (S1) ◽  
pp. S182-S194 ◽  
Author(s):  
Peter D'Eustachio
Keyword(s):  
Mouse Chromosome ◽  
Chromosome 12

Mouse Chromosome 12

1999 ◽  
Vol 10 (10) ◽  
pp. 953-953 ◽  
Author(s):  
Peter D'Eustachio ◽  
Roy Riblet
Keyword(s):  
Mouse Chromosome ◽  
Chromosome 12

Imprinting analysis in the Acrodysplasia region of mouse chromosome 12

2009 ◽  
Vol 30 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Erin N. McMurray ◽  
Eric D. Rogers ◽  
Jennifer V. Schmidt
Keyword(s):  
Mouse Chromosome ◽  
Genomic Imprinting ◽  
Critical Region ◽  
The Other ◽  
Chromosome 12 ◽  
Imprinted Genes ◽  
Skeletal Abnormalities ◽  
Mouse Mutation ◽  
Parent Of Origin

The insertional mouse mutation Adp (Acrodysplasia) confers a parent-of-origin developmental phenotype, with animals inheriting the mutation from their father showing skeletal abnormalities, whereas those inheriting the mutation from their mother are normal. This parental-specific phenotype, along with mapping of the insertion to a region of chromosome 12 proposed to contain imprinted genes, suggested that disruption of genomic imprinting might underlie the Adp phenotype. Genomic imprinting is the process by which autosomal genes are epigenetically silenced on one of the two parental alleles; imprinting mutation phenotypes manifest after inheritance from one parent but not the other. Imprinted genes typically occur in dense clusters that contain few non-imprinted genes and therefore representative genes from the Adp critical region could be assayed to identify any imprinted domains. None of the genes analysed were found to be imprinted, however, suggesting that other explanations for the Adp phenotype must be considered.

Mouse chromosome 12

1997 ◽  
Vol 7 (S1) ◽  
pp. S209-S222 ◽  
Author(s):  
Peter D’Eustachio ◽  
Roy Riblet
Keyword(s):  
Mouse Chromosome ◽  
Chromosome 12

A Genome Segment on Mouse Chromosome 12 Determines Maxillary Growth

2007 ◽  
Vol 86 (12) ◽  
pp. 1203-1206 ◽  
Author(s):  
J. Oh ◽  
C.J. Wang ◽  
M. Poole ◽  
E. Kim ◽  
R.C. Davis ◽  
...  
Keyword(s):  
Mouse Chromosome ◽  
Chromosome 12 ◽  
Mouse Strains ◽  
Snout Length ◽  
Face Width ◽  
Maxillofacial Development ◽  
A Genome ◽  
Imaging Results ◽  
Trait Locus ◽  
Anterior Posterior

The primary and modifier genes that regulate normal maxillofacial development are unknown. Previous quantitative trait locus (QTL) analyses using the F2 progeny of 2 mouse strains, DBA/2J (short snout/wide face) and C57BL/6J (long snout/narrow face), revealed a significant logarithm-of-odds (LOD) score for snout length on mouse chromosome 12 at 44 centimorgan (cM). We further sought to validate this locus contributing to anterior-posterior dimensions of the upper mid-face at the D12Mit7 marker in a 44-centimorgan portion of chromosome 12. Congenic mice carrying introgressed DNA from DBA/2J on a C57BL/6J background were selected for submental vertex cephalometric imaging. Results confirmed QTLs, determining that short snout length (P < 0.05) and face width relative to snout length (P < 0.01) were present in the 44-cM region of chromosome 12. We conclude that one or more genes contributing to the shape of the maxillary complex are located near 44 cM of mouse chromosome 12.

Mouse chromosome 12

1993 ◽  
Vol 4 (S1) ◽  
pp. S176-S191 ◽  
Author(s):  
Peter D'Eustachio
Keyword(s):  
Mouse Chromosome ◽  
Chromosome 12

Imprinting of a Small Nucleolar RNA Gene on Mouse Chromosome 12

Genomics ◽  
2002 ◽  
Vol 79 (4) ◽  
pp. 483-486 ◽  
Author(s):  
Masafumi Shimoda ◽  
Sumiyo Morita ◽  
Yayoi Obata ◽  
Yusuke Sotomaru ◽  
Tomohiro Kono ◽  
...  
Keyword(s):  
Mouse Chromosome ◽  
Chromosome 12 ◽  
Small Nucleolar Rna ◽  
Nucleolar Rna

scholarly journals The Epimorphin Gene Is Highly Conserved among Humans, Mice, and Rats and Maps to Human Chromosome 7, Mouse Chromosome 5, and Rat Chromosome 12

Genomics ◽  
1996 ◽  
Vol 37 (3) ◽  
pp. 386-389 ◽  
Author(s):  
Hongbin Zha ◽  
Elaine F. Remmers ◽  
Claude Szpirer ◽  
Josiane Szpirer ◽  
Heying Zhang ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Mouse Chromosome ◽  
Chromosome 7 ◽  
Chromosome 12 ◽  
Chromosome 5 ◽  
Human Chromosome 7
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