scholarly journals Gradual Release of Sperm Bound Sex-Peptide Controls Female Postmating Behavior in Drosophila

2005 ◽  
Vol 15 (3) ◽  
pp. 207-213 ◽  
Author(s):  
Jing Peng ◽  
Shanjun Chen ◽  
Susann Büsser ◽  
Huanfa Liu ◽  
Thomas Honegger ◽  
...  
Keyword(s):  
Sex Peptide ◽  
Postmating Behavior ◽  
Gradual Release

scholarly journals Oxidative cyclo-rearrangement of helicenes into chiral nanographenes

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Chengshuo Shen ◽  
Guoli Zhang ◽  
Yongle Ding ◽  
Na Yang ◽  
Fuwei Gan ◽  
...  
Keyword(s):  
Functional Materials ◽  
Optical Devices ◽  
Oxidative Cyclization ◽  
Synthetic Chemistry ◽  
Aromatic Rings ◽  
Cyclization Reactions ◽  
Rearrangement Reaction ◽  
Skeletal Reconstruction ◽  
Gradual Release

AbstractNanographenes are emerging as a distinctive class of functional materials for electronic and optical devices. It is of remarkable significance to enrich the precise synthetic chemistry for these molecules. Herein, we develop a facile strategy to recompose helicenes into chiral nanographenes through a unique oxidative cyclo-rearrangement reaction. Helicenes with 7~9 ortho-fused aromatic rings are firstly oxidized and cyclized, and subsequently rearranged into nanographenes with an unsymmetrical helicoid shape through sequential 1,2-migrations. Such skeletal reconstruction is virtually driven by the gradual release of the strain of the highly distorted helicene skeleton. Importantly, the chirality of the helicene precursor can be integrally inherited by the resulting nanographene. Thus, a series of chiral nanographenes are prepared from a variety of carbohelicenes and heterohelicenes. Moreover, such cyclo-rearrangement reaction can be sequentially or simultaneously associated with conventional oxidative cyclization reactions to ulteriorly enrich the geometry diversity of nanographenes, aiming at innovative properties.

Clay-based nanocomposite hydrogel with attractive mechanical properties and sustained bioactive ion release for bone defect repair

2021 ◽  
Author(s):  
Xinyun Zhai ◽  
Changshun Ruan ◽  
Jie Shen ◽  
Chuping Zheng ◽  
Xiaoli Zhao ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Defect ◽  
Nanocomposite Hydrogel ◽  
Ion Release ◽  
Bone Defect Repair ◽  
Defect Repair ◽  
Gradual Release

Using nanoclay as the physical crosslinker, a novel clay-based nanocomposite hydrogel with attractive mechanical properties has be obtained, and the gradual release of intrinsic Mg2+ and Si4+ endows the system with excellent osteogenesis.

scholarly journals Increasing the Power of Polyphenols through Nanoencapsulation for Adjuvant Therapy against Cardiovascular Diseases

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4621
Author(s):  
Lucileno Rodrigues Trindade ◽  
Davi Vieira Teixeira da da Silva ◽  
Diego dos Santos Baião ◽  
Vania Margaret Flosi Paschoalin
Keyword(s):  
Clinical Trials ◽  
Cardiovascular Diseases ◽  
Adjuvant Therapy ◽  
Vascular Diseases ◽  
Ppar Γ ◽  
Epidemiological Surveys ◽  
Genes Encoding ◽  
And Oxidative Stress ◽  
Gradual Release ◽  
Inflammatory Action

Polyphenols play a therapeutic role in vascular diseases, acting in inherent illness-associate conditions such as inflammation, diabetes, dyslipidemia, hypertension, and oxidative stress, as demonstrated by clinical trials and epidemiological surveys. The main polyphenol cardioprotective mechanisms rely on increased nitric oxide, decreased asymmetric dimethylarginine levels, upregulation of genes encoding antioxidant enzymes via the Nrf2-ARE pathway and anti-inflammatory action through the redox-sensitive transcription factor NF-κB and PPAR-γ receptor. However, poor polyphenol bioavailability and extensive metabolization restrict their applicability. Polyphenols carried by nanoparticles circumvent these limitations providing controlled release and better solubility, chemical protection, and target achievement. Nano-encapsulate polyphenols loaded in food grade polymers and lipids appear to be safe, gaining resistance in the enteric route for intestinal absorption, in which the mucoadhesiveness ensures their increased uptake, achieving high systemic levels in non-metabolized forms. Nano-capsules confer a gradual release to these compounds, as well as longer half-lives and cell and whole organism permanence, reinforcing their effectiveness, as demonstrated in pre-clinical trials, enabling their application as an adjuvant therapy against cardiovascular diseases. Polyphenol entrapment in nanoparticles should be encouraged in nutraceutical manufacturing for the fortification of foods and beverages. This study discusses pre-clinical trials evaluating how nano-encapsulate polyphenols following oral administration can aid in cardiovascular performance.

Homology modeling and molecular docking studies of Drosophila and Aedes sex peptide receptors

2016 ◽  
Vol 66 ◽  
pp. 115-122 ◽  
Author(s):  
Jeong-hyun Kim ◽  
Soo-Kyung Kim ◽  
Jae-Hyuk Lee ◽  
Young-Joon Kim ◽  
William A. Goddard ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Homology Modeling ◽  
Docking Studies ◽  
Peptide Receptors ◽  
Molecular Docking Studies ◽  
Sex Peptide

scholarly journals Afforestation of Former Farmland with High-value Hardwoods

1991 ◽  
Vol 67 (3) ◽  
pp. 209-212 ◽  
Author(s):  
F. W. von Althen
Keyword(s):  
Early Years ◽  
Intensive Management ◽  
High Quality ◽  
Close Spacing ◽  
Hardwood Species ◽  
Competition Control ◽  
Stem Development ◽  
Gradual Release ◽  
Poor Drainage

For satisfactory growth, most high-value hardwood species demand a deep, fertile, moist but well drained soil. Intensive competition control during the early years after planting is a necessity. Close spacing is recommended, with gradual release of crop trees to promote high-quality stem development. For good hardwood growth on soils of marginal fertility or poor drainage or on sites where intensive management cannot be guaranteed, it is recommended that a mixture of several hardwood species be planted.

scholarly journals Pyrite and pyrrhotite in a prograde metamorphic sequence, Hyland River region, SE Yukon: implications for orogenic gold

2021 ◽  
Author(s):  
C D W Padget ◽  
D R M Pattison ◽  
D P Moynihan ◽  
O Beyssac
Keyword(s):  
Raman Spectroscopy ◽  
Phase Equilibrium ◽  
Source Region ◽  
Carbonaceous Material ◽  
Orogenic Gold ◽  
Metamorphic Rocks ◽  
Small Interval ◽  
River Region ◽  
Gradual Release ◽  
Fluid Release

The distribution of pyrite and pyrrhotite is documented within an andalusite-sillimanite type (high-temperature, low-pressure) metasedimentary succession exposed in the Hyland River region of southeastern Yukon, Canada. The following metamorphic zones are recognized: chlorite, biotite, cordierite/staurolite (porphyroblast-in), andalusite, sillimanite, and K-feldspar + sillimanite. Pyrite occurs in the chlorite zone through the biotite zone, while pyrrhotite occurs from the chlorite zone to K-feldspar + sillimanite zone. The pyrite-pyrrhotite transition, therefore, occupies an interval in the chlorite and lower biotite zones that is terminated upgrade by a pyrite-out isograd in the upper part of the biotite zone or lowest grade part of the cordierite/staurolite zone. Pressure and temperature conditions of the rocks were estimated from phase equilibrium modelling and from Raman spectroscopy of carbonaceous material (RSCM) thermometry. Modelling indicates pressures of 3.7-4.1 kbar with temperatures of ~425 °C at the biotite isograd, 560-570 °C for chlorite-out/porphyroblast-in, ~575 °C for andalusite-in, 575-600 °C for the sillimanite isograd, and 645-660 °C at the K-feldspar + sillimanite isograd. RSCM temperatures are greater than or equal to 420 °C in the Chl zone, 500 °C at the Bt isograd, 525-550 °C for porphyroblast-in isograd, ~550 °C at the And isograd, and 580 °C at the Sil isograd. These results suggest the pyrite-pyrrhotite transition occurs from less than or equal to 420°C to ~560 °C. Thermodynamic modelling shows 0.6 wt. % H2O is released during metamorphism over the ~140 °C interval of the pyrite-pyrrhotite transition. The gradual release of fluid in the biotite zone is interpreted to have broadened the pyrite-pyrrhotite transition compared to other studies that predict a small interval of vigorous fluid release associated with volumetric chlorite consumption. Samples from the pyrite-pyrrhotite transition zone contain lower whole rock and pyrite Au values than samples from unmetamorphosed/lower rocks, suggesting that Au was removed from the rock at conditions below the pyrite-pyrrhotite transition (<420 °C). The chlorite zone and higher-grade metamorphic rocks of the Hyland River area do not appear to be a plausible source region for orogenic gold.

scholarly journals Rendimiento y eficiencia en el uso del agua de un genotipo de chile serrano (Capsicum annuum L.) Producido bajo fertilización orgánica e inorgánica en casa sombra

2021 ◽  
pp. 47329-47332
Keyword(s):  
Capsicum Annuum ◽  
Fruit Weight ◽  
Organic Fertilization ◽  
The Third ◽  
Capsicum Annuum L ◽  
Weight Yield ◽  
High Yields ◽  
The University ◽  
Gradual Release ◽  
Research Show

The objective of this research was to evaluate the effect of organic fertilization, compared to inorganic and a combination of both in the cultivation of serrano pepper (Capsicum annuum L.) under shade net at the University of Sonora. The variables that were evaluated were: fruit weight, yield, length and diameter of fruit, as well as efficiency of water use. For the weight of the fruit per plant, no significant differences were observed between treatments in the first two cuts, however, for the third cut if there were significant differences, the best treatments were inorganic fertilization and the mixture of inorganic plus algae extracts with 280.29 and 212.21 g respectively. For the fourth and fifth cut the trend was in the same way up to the final average resulting in the best treatment inorganic fertilization with 233.94 g per plant followed by the mixture of inorganic plus seaweed extract with 166.75 g per plant. Regarding the yield, it can be observed that from the third cut the treatments that contained inorganic resulted with the highest yield, resulting in the total average inorganic fertilization with 38665.77 kg ha-1 and inorganic fertilization plus algae extract with 27514.08 kg ha-1. The results obtained from this research show that organic fertilization does not provide high yields compared to inorganic because of the gradual release of nutrients to the plant.

scholarly journals Growth Factors & Stem Cells Entrapment in Bio Compatible & Biodegradable Nano Particles to Prevent Early Degradation & Facilitate Gradual Release

2021 ◽  
Author(s):  
ANURUDDHA A. H. M. P. ◽  
C. A. N. FERNANDO ◽  
YOSHIHISA SAIDA ◽  
MINORU SAKURABA
Keyword(s):  
Stem Cells ◽  
Growth Factors ◽  
Extraction Process ◽  
Nano Particles ◽  
The Core ◽  
Experimental Process ◽  
One Step ◽  
Treatment Procedures ◽  
Early Degradation ◽  
Gradual Release

Abstract The use of growth factors and stem cells as the core treating agents is one step into creating a biocompatible Solid Lipid Nano Particles (SLNP) for treatments. Apart from obtaining these growth factors and stem cells from the patients, using the bi-product of the extraction process which is the lipid of the patient for the production of the SLNP assures the final product to be biocompatible and of a unique structure. The use of autologous cells and proteins from the patients makes the entire process medically ethical and more viable for treatment procedures. This article, thus discusses on the experimental process of developing such SLNP and the introduction of the relevant medical contraption designed uniquely for the procedure inclusive of a specified membrane.

A functioning ovary is not required for sex peptide to reduce receptivity to mating in D. melanogaster

2007 ◽  
Vol 53 (4) ◽  
pp. 343-348 ◽  
Author(s):  
Andrew I. Barnes ◽  
James M. Boone ◽  
Linda Partridge ◽  
Tracey Chapman
Keyword(s):  
Sex Peptide
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