scholarly journals Using a personalized decision support algorithm for dosing in warfarin treatment: A randomised controlled trial

Author(s):  
Peter Brønnum Nielsen ◽  
Søren Lundbye-Christensen ◽  
Meriam van der Male ◽  
Torben Bjerregaard Larsen
Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 706 ◽  
Author(s):  
George Moschonis ◽  
Maria Michalopoulou ◽  
Konstantina Tsoutsoulopoulou ◽  
Elpis Vlachopapadopoulou ◽  
Stefanos Michalacos ◽  
...  

We examined the effectiveness of a computerised decision-support tool (DST), designed for paediatric healthcare professionals, as a means to tackle childhood obesity. A randomised controlled trial was conducted with 65 families of 6–12-year old overweight or obese children. Paediatricians, paediatric endocrinologists and a dietitian in two children’s hospitals implemented the intervention. The intervention group (IG) received personalised meal plans and lifestyle optimisation recommendations via the DST, while families in the control group (CG) received general recommendations. After three months of intervention, the IG had a significant change in dietary fibre and sucrose intake by 4.1 and −4.6 g/day, respectively. In addition, the IG significantly reduced consumption of sweets (i.e., chocolates and cakes) and salty snacks (i.e., potato chips) by −0.1 and −0.3 portions/day, respectively. Furthermore, the CG had a significant increase of body weight and waist circumference by 1.4 kg and 2.1 cm, respectively, while Body Mass Index (BMI) decreased only in the IG by −0.4 kg/m2. However, the aforementioned findings did not differ significantly between study groups. In conclusion, these findings indicate the dynamics of the DST in supporting paediatric healthcare professionals to improve the effectiveness of care in modifying obesity-related behaviours. Further research is needed to confirm these findings.


2017 ◽  
Vol 9 (2) ◽  
pp. 131 ◽  
Author(s):  
Annemarei Ranta ◽  
Mark Weatherall ◽  
John Gommans ◽  
Murray Tilyard ◽  
Des Odea ◽  
...  

Abstract AIMS Many transient ischaemic attack (TIA) patients receive initial assessments by general practitioners (GPs). In a randomised controlled trial (RCT) we showed that BPAC Inc. TIA/stroke electronic decision support (EDS) for GPs improves patient outcomes and guideline adherence. This secondary analysis assesses the impact of trial associated enhanced GP access to radiological investigation. METHODS Post-hoc analysis of a multi-centre, single blind, parallel group, cluster RCT comparing TIA/stroke EDS guided GP management with usual care to assess whether imaging requests and their appropriateness differed between study groups. RESULTS GPs requested 15/291 (5.2%) carotid ultrasounds and 19/291 (6.5%) computed tomography (CT) head scans. Scans were obtained more frequently in the intervention group (ultrasound cluster adjusted OR (95% CI) 1.41 (0.44 to 4.49), P = 0.56 and CT 13.8 (1.7 to 110.7), P < 0.001). All CTs were clinically appropriate. More ultrasounds were appropriate in the EDS group (cluster adjusted OR (95% CI) of 8.4 (0.39 to 92.3), P = 0.18). Overall investigation costs did not differ between groups (P = 0.83). Some apparent avoidable imaging duplication occurred where patients were subsequently assessed by secondary services. CONCLUSION In the setting of a RCT assessing GP electronic decision support, frequency of GP initiated imaging requests was low and largely appropriate especially in the setting of EDS use. Thus enhanced GP imaging access as part of the EDS tool did not result in inappropriate or excessive GP imaging requests. However, some duplication occurred and practitioners need to ensure that test referrals and results are adequately communicated between sectors.


BMJ ◽  
2004 ◽  
Vol 328 (7437) ◽  
pp. 437-438 ◽  
Author(s):  
Ellen Murray ◽  
David Fitzmaurice ◽  
Debbie McCahon ◽  
Chris Fuller ◽  
Hardeep Sandhur

2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
Ana Requena

Abstract Dr Requena will share new data from a pilot randomised controlled trial of a novel integrated multi-infection screening digital decision support tool, to promote screening for multiple infections in primary care in Spain among presenting migrants.


2006 ◽  
Vol 62 (9) ◽  
pp. 2267-2278 ◽  
Author(s):  
Tim Rapley ◽  
Carl May ◽  
Ben Heaven ◽  
Madeline Murtagh ◽  
Ruth Graham ◽  
...  

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