scholarly journals Different patterns of short-term memory deficit in Alzheimer's disease, Parkinson's disease and subjective cognitive impairment

Cortex ◽  
2020 ◽  
Vol 132 ◽  
pp. 41-50
Author(s):  
Nahid Zokaei ◽  
Annie Sillence ◽  
Annika Kienast ◽  
Daniel Drew ◽  
Olivia Plant ◽  
...  
2021 ◽  
pp. 155005942199714
Author(s):  
Lucia Zinno ◽  
Anna Negrotti ◽  
Chiara Falzoi ◽  
Giovanni Messa ◽  
Matteo Goldoni ◽  
...  

Introduction. An easily accessible and inexpensive neurophysiological technique such as conventional electroencephalography may provide an accurate and generally applicable biomarker capable of differentiating dementia with Lewy bodies (DLB) from Alzheimer’s disease (AD) and Parkinson’s disease-associated dementia (PDD). Method. We carried out a retrospective visual analysis of resting-state electroencephalography (EEG) recording of 22 patients with a clinical diagnosis of 19 probable and 3 possible DLB, 22 patients with probable AD and 21 with PDD, matched for age, duration, and severity of cognitive impairment. Results. By using the grand total EEG scoring method, the total score and generalized rhythmic delta activity frontally predominant (GRDAfp) alone or, even better, coupled with a slowing of frequency of background activity (FBA) and its reduced reactivity differentiated DLB from AD at an individual level with an high accuracy similar to that obtained with quantitative EEG (qEEG). GRDAfp alone could also differentiate DLB from PDD with a similar level of diagnostic accuracy. AD differed from PDD only for a slowing of FBA. The duration and severity of cognitive impairment did not differ between DLB patients with and without GRDAfp, indicating that this abnormal EEG pattern should not be regarded as a disease progression marker. Conclusions. The findings of this investigation revalorize the role of conventional EEG in the diagnostic workup of degenerative dementias suggesting the potential inclusion of GRDAfp alone or better coupled with the slowing of FBA and its reduced reactivity, in the list of supportive diagnostic biomarkers of DLB.


Cortex ◽  
2017 ◽  
Vol 88 ◽  
pp. 201-204 ◽  
Author(s):  
Yuying Liang ◽  
Yoni Pertzov ◽  
Jennifer M. Nicholas ◽  
Susie M.D. Henley ◽  
Sebastian Crutch ◽  
...  

2016 ◽  
Vol 127 (6) ◽  
pp. 2423-2435 ◽  
Author(s):  
Robert M. Chapman ◽  
Margaret N. Gardner ◽  
Mark Mapstone ◽  
Rafael Klorman ◽  
Anton P. Porsteinsson ◽  
...  

Brain ◽  
2008 ◽  
Vol 132 (4) ◽  
pp. 1057-1066 ◽  
Author(s):  
M. A. Parra ◽  
S. Abrahams ◽  
K. Fabi ◽  
R. Logie ◽  
S. Luzzi ◽  
...  

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