Impaired emotional memory enhancement on recognition of pictorial stimuli in Alzheimer's disease: No influence of the nature of encoding

Cortex ◽  
2014 ◽  
Vol 50 ◽  
pp. 32-44 ◽  
Author(s):  
Hanna Chainay ◽  
Alexandra Sava ◽  
George A. Michael ◽  
Lionel Landré ◽  
Rémy Versace ◽  
...  
Cortex ◽  
2015 ◽  
Vol 65 ◽  
pp. 89-101 ◽  
Author(s):  
Alina-Alexandra Sava ◽  
Claire Paquet ◽  
Pierre Krolak-Salmon ◽  
Julien Dumurgier ◽  
Jacques Hugon ◽  
...  

2000 ◽  
Vol 14 (1) ◽  
pp. 82-92 ◽  
Author(s):  
Stephan B. Hamann ◽  
Elena S. Monarch ◽  
Felicia C. Goldstein

Emotion ◽  
2002 ◽  
Vol 2 (2) ◽  
pp. 118-134 ◽  
Author(s):  
Elizabeth A. Kensinger ◽  
Barbara Brierley ◽  
Nick Medford ◽  
John H. Growdon ◽  
Suzanne Corkin

1998 ◽  
Vol 172 (5) ◽  
pp. 425-428 ◽  
Author(s):  
Manabu Ikeda ◽  
Etsuro Mori ◽  
Nobutsugu Hirono ◽  
Toru Imamura ◽  
Tatsuo Shimomura ◽  
...  

BackgroundEmotional memory is a special category of memory for events arousing strong emotions. To investigate the effects of emotional involvement on memory retention in individuals with Alzheimer's disease we studied peoples' memories of distressing experiences during a devastating earthquake.MethodFifty-one subjects with probable Alzheimer's disease who experienced the Kobe earthquake at home in the greater Kobe area were studied. Memories of the earthquake were assessed 6 and 10 weeks after the disaster in semi-structured interviews, and were compared with memories of a magnetic resonance imaging (MRI) examination given after the earthquake.ResultsForty-four (86.3%) of the subjects remembered the earthquake and 16 (31.4%) of subjects remembered the MRI experience. Factual content of the earthquake was lost in most of the subjects.ConclusionsFear reinforces memory retention of an episode in subjects with Alzheimer's disease but does not enhance retention of its context, despite repeated exposure to the information.


2020 ◽  
Vol 11 (3) ◽  
pp. 354-359
Author(s):  
O. G. Berchenko ◽  
N. O. Levicheva ◽  
D. O. Bevzyuk ◽  
V. V. Sokolik

Memory impairment is a hallmark of Alzheimer’s disease. The clinical diagnosis of the disease is made in the later stages of its development, when specific therapy of the disease is not always effective. Therefore, the detection of early behavioral manifestations of memory disorders in the development of the disease will allow the use of preventive therapy aimed at stopping the death of neurons in brain structures. A neuroethological study of working, spatial, and emotional memory was performed in rats 15–16 months of age with a model of early manifestations of Alzheimer’s disease induced by stereotactic administration of β-amyloid peptide 40 aggregates into the hippocampus. Changes in the neuroethological components of working and spatial memory have been identified. Testing of working memory showed a violation in rats of recognizing the shape of identical objects, reducing experimental activity to unfamiliar objects and their differentiation. Spatial orientation disorders have been identified in the Barnes labyrinth. Emotional memory research has shown the preservation of innate forms of protective adaptive behaviour. At the same time, vegetative indicators reflected an increase in emotional tension. Intranasal administration of liposomal miRNA miR-101 involved in liposomes to rats with a model of early manifestations of Alzheimer’s disease improved neuroethological parameters of working and spatial memory. Restoration of the level of research activity and differentiation of familiar and unfamiliar objects in the testing of working memory in rats has been established. Spatial memory in Barnes labyrinth testing was improved by reproducing spatial orientation skills and relieving emotional stress. Thus, the intranasal use of miR-101 in Alzheimer’s disease is a promising approach to prevent the development of amyloidosis and preserve memory in the early manifestations of Alz-heimer’s disease.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Akira Okada ◽  
Junko Matsuo

Highly emotional events in daily life can be preserved in memory and such memory is generally referred to as emotional memory. Some reports have demonstrated that emotional memory is also found in patients with Alzheimer’s disease (AD). However, to our knowledge, there have been no reports about how long memory retention for emotional events can continue in patients with AD. In this paper, we present two patients with AD who lost an immediate family member during followup and retained the memory over a long period despite progression of the AD.


2003 ◽  
Vol 999 (1) ◽  
pp. 381-384 ◽  
Author(s):  
NOLWENN QUONIAM ◽  
ANNE-MARIE ERGIS ◽  
PHILIPPE FOSSATI ◽  
ISABELLE PERETZ ◽  
SÉVERINE SAMSON ◽  
...  

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