Brain connectivity during resting state and subsequent working memory task predicts behavioural performance

Cortex ◽  
2012 ◽  
Vol 48 (9) ◽  
pp. 1187-1196 ◽  
Author(s):  
Roser Sala-Llonch ◽  
Cleofé Peña-Gómez ◽  
Eider M. Arenaza-Urquijo ◽  
Dídac Vidal-Piñeiro ◽  
Nuria Bargalló ◽  
...  
Keyword(s):  
Working Memory ◽  
Resting State ◽  
Brain Connectivity ◽  
Memory Task ◽  
Behavioural Performance

scholarly journals Declined functional connectivity of white matter during rest and working memory tasks associates with cognitive impairments in schizophrenia

2020 ◽  
Author(s):  
Yurui Gao ◽  
Muwei Li ◽  
Anna S Huang ◽  
Adam W Anderson ◽  
Zhaohua Ding ◽  
...  
Keyword(s):  
Working Memory ◽  
White Matter ◽  
Functional Connectivity ◽  
Resting State ◽  
Spatial Working Memory ◽  
Cognitive Impairments ◽  
Memory Task ◽  
Brain Network ◽  
Blood Oxygenation ◽  
Cerebral Peduncle

BACKGROUND: Schizophrenia, characterized by cognitive impairments, arises from a disturbance of brain network. Pathological changes in white matter (WM) have been indicated as playing a role in disturbing neural connectivity in schizophrenia. However, deficits of functional connectivity (FC) in individual WM bundles in schizophrenia have never been explored; neither have cognitive correlates with those deficits. METHODS: Resting-state and spatial working memory task fMRI images were acquired on 67 healthy subjects and 84 patients with schizophrenia. The correlations in blood-oxygenation-level-dependent (BOLD) signals between 46 WM and 82 gray matter regions were quantified, analyzed and compared between groups under three scenarios (i.e., resting state, retention period and entire time of a spatial working memory task). Associations of FC in WM with cognitive assessment scores were evaluated for three scenarios. RESULTS: FC deficits were significant (p<.05) in external capsule, cingulum, uncinate fasciculus, genu and body of corpus callosum under all three scenarios. Deficits were also present in the anterior limb of the internal capsule and cerebral peduncle in task scenario. Decreased FCs in specific WM bundles associated significantly (p<.05) with cognitive impairments in working memory, processing speed and/or cognitive control. CONCLUSIONS: Decreases in FC are evident in several WM bundles in patients with schizophrenia and are significantly associated with cognitive impairments during both rest and working memory tasks. Furthermore, working memory tasks expose FC deficits in more WM bundles and more cognitive associates in schizophrenia than resting state does.

scholarly journals Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Monika Pupíková ◽  
Patrik Šimko ◽  
Martin Gajdoš ◽  
Irena Rektorová
Keyword(s):  
Working Memory ◽  
Resting State ◽  
Large Scale ◽  
Memory Task ◽  
Resting State Fmri ◽  
Resting State Functional Connectivity ◽  
Double Blind ◽  
Frontoparietal Network ◽  
Cognitive Speed ◽  
The Right

Many cognitive functions, including working memory, are processed within large-scale brain networks. We targeted the right frontoparietal network (FPN) with one session of transcranial direct current stimulation (tDCS) in an attempt to modulate the cognitive speed of a visual working memory task (WMT) in 27 young healthy subjects using a double-blind crossover design. We further explored the neural underpinnings of induced changes by performing resting-state fMRI prior to and immediately after each stimulation session with the main focus on the interaction between a task-positive FPN and a task-negative default mode network (DMN). Twenty minutes of 2 mA anodal tDCS was superior to sham stimulation in terms of cognitive speed manipulation of a subtask with processing of objects and tools in unconventional views (i.e., the higher cognitive load subtask of the offline WMT). This result was linked to the magnitude of resting-state functional connectivity decreases between the stimulated FPN seed and DMN seeds. We provide the first evidence for the action reappraisal mechanism of object and tool processing. Modulation of cognitive speed of the task by tDCS was reflected by FPN-DMN cross-talk changes.

scholarly journals Resting-state functional brain connectivity predicts cognitive performance: An exploratory study on a time-based prospective memory task

2021 ◽  
Vol 402 ◽  
pp. 113130
Author(s):  
Andrea Zangrossi ◽  
Giovanni Zanzotto ◽  
Fabio Lorenzoni ◽  
Giuliana Indelicato ◽  
Fabio Cannas Aghedu ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Prospective Memory ◽  
Resting State ◽  
Exploratory Study ◽  
Brain Connectivity ◽  
Memory Task ◽  
Prospective Memory Task ◽  
Functional Brain

scholarly journals Capacity differences in working memory based on resting state brain networks

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mariko Osaka ◽  
Mizuki Kaneda ◽  
Miyuki Azuma ◽  
Ken Yaoi ◽  
Tetsuya Shimokawa ◽  
...  
Keyword(s):  
Working Memory ◽  
Task Performance ◽  
Resting State ◽  
Attentional Control ◽  
Memory Task ◽  
High Capacity ◽  
Network Connectivity ◽  
Anterior Cingulate ◽  
Single Task ◽  
Task Conditions

AbstractHerein, we compared the connectivity of resting-state networks between participants with high and low working memory capacity groups. Brain network connectivity was assessed under both resting and working memory task conditions. Task scans comprised dual-task (reading sentences while memorizing target words) and single-task (reading sentences) conditions. The low capacity group showed relatively stronger connectivity during resting-state in most brain regions, and the high capacity group showed a stronger connectivity between the medial prefrontal and posterior parietal cortices. During task performance, the dorsal attention and salience networks were relatively strongly connected in the high capacity group. In the comparison between dual- and single-task conditions, increased coupling between the anterior cingulate cortex and other attentional control-related areas were noted in the high capacity group. These findings suggest that working memory differences are related with network connectivity variations in attentional control-associated regions during both resting and task performance conditions.

scholarly journals Theta Oscillations and Source Connectivity During Complex Audiovisual Object Encoding in Working Memory

2021 ◽  
Vol 15 ◽  
Author(s):  
Yuanjun Xie ◽  
Yanyan Li ◽  
Haidan Duan ◽  
Xiliang Xu ◽  
Wenmo Zhang ◽  
...  
Keyword(s):  
Working Memory ◽  
Brain Connectivity ◽  
Memory Task ◽  
Theta Oscillations ◽  
Neural Oscillations ◽  
Neural Signals ◽  
Sensory Modalities ◽  
Cortical Regions ◽  
Oscillation Characteristics ◽  
Single Modality

Working memory is a limited capacity memory system that involves the short-term storage and processing of information. Neuroscientific studies of working memory have mostly focused on the essential roles of neural oscillations during item encoding from single sensory modalities (e.g., visual and auditory). However, the characteristics of neural oscillations during multisensory encoding in working memory are rarely studied. Our study investigated the oscillation characteristics of neural signals in scalp electrodes and mapped functional brain connectivity while participants encoded complex audiovisual objects in a working memory task. Experimental results showed that theta oscillations (4–8 Hz) were prominent and topographically distributed across multiple cortical regions, including prefrontal (e.g., superior frontal gyrus), parietal (e.g., precuneus), temporal (e.g., inferior temporal gyrus), and occipital (e.g., cuneus) cortices. Furthermore, neural connectivity at the theta oscillation frequency was significant in these cortical regions during audiovisual object encoding compared with single modality object encoding. These results suggest that local oscillations and interregional connectivity via theta activity play an important role during audiovisual object encoding and may contribute to the formation of working memory traces from multisensory items.

scholarly journals Brain Connectivity in Ateles geoffroyi: Resting-State Functional Magnetic Resonance Imaging of Working Memory and Executive Control

2019 ◽  
Vol 93 (1) ◽  
pp. 19-33
Author(s):  
Diana Platas-Neri ◽  
Silvia Hidalgo-Tobón ◽  
Fernando Chico-Ponce de León ◽  
Jairo Muñoz-Delgado ◽  
Kimberley A. Phillips ◽  
...  
Keyword(s):  
Working Memory ◽  
Executive Control ◽  
Resting State ◽  
Information Transfer ◽  
Brain Connectivity ◽  
Brain Regions ◽  
Primate Species ◽  
Ateles Geoffroyi ◽  
Healthy Human ◽  
The Gift

The objective of this research was to describe the organization and connectivity of the working memory (WM) and executive control (EC) networks in Ateles geoffroyi in resting-state conditions. Recent studies have shown that resting-state activity may underlie rudimentary brain functioning, showing that several brain regions can be tonically active at rest, maximizing the efficiency of information transfer while preserving a low physical connection cost. Whole-brain resting-state images were acquired from three healthy adult Ateles monkeys (2 females, 1 male; mean age 10.5 ± SD 2.5 years). Data were analyzed with independent component analysis, and results were grouped together using the GIFT software. The present study compared the EC and WM networks obtained with human data and with results found in the literature in other primate species. Nine resting-state networks were found, which were similar to resting networks found in healthy human adults in the prefrontal basal portion and frontopolar area. Additionally, components of the WM network were found to be extending into the hypothalamus and the olfactory areas. A key finding was the discovery of connections in the WM and EC networks to the hypothalamus, the motor cortex, and the entorhinal cortex, suggesting that information is integrated from larger brain areas. The correlated areas suggest that many elements of WM and EC may be conserved across primate species. Characterization of these networks in resting-state conditions in nonhuman primate brains is a fundamental prerequisite for understanding of the neural bases underlying the evolution and function of this cognitive system.

NIRS Captured Changes in Resting State Functional Connectivity after Performing a Working Memory Task

2012 ◽  
Author(s):  
Laleh Najafizadeh ◽  
Fatima Chowdhry ◽  
Jana Kainerstorfer ◽  
Nader Shahni Karamzadeh ◽  
Franck Amyot ◽  
...  
Keyword(s):  
Working Memory ◽  
Functional Connectivity ◽  
Resting State ◽  
Memory Task ◽  
Resting State Functional Connectivity

REDUCED ABILITY TO ENGAGE DEFAULT-MODE BRAIN REGIONS DURING THE RESTING-STATE PERIODS OF A WORKING MEMORY TASK IN RECENT-ONSET SCHIZOPHRENIA

2010 ◽  
Vol 117 (2-3) ◽  
pp. 347
Author(s):  
Sarah C. Jacobson ◽  
Katherine H. Karlsgodt ◽  
Jacqueline H. Sanz ◽  
Theo G.M. van Erp ◽  
Keith H. Nuechterlein ◽  
...  
Keyword(s):  
Working Memory ◽  
Resting State ◽  
Memory Task ◽  
Brain Regions ◽  
Default Mode ◽  
Recent Onset
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