Highly porous 3D sponge-like shape memory polymer for tissue engineering application with remote actuation potential

2019 ◽  
Vol 184 ◽  
pp. 107874 ◽  
Author(s):  
Mohadeseh Zare ◽  
Nader Parvin ◽  
Molamma P. Prabhakaran ◽  
Jamshid Aghazadeh Mohandesi ◽  
Seeram Ramakrishna
2020 ◽  
Vol 20 (9) ◽  
pp. 5356-5359
Author(s):  
Tae In Hwang ◽  
Joon Yeon Moon ◽  
Jeong In Kim ◽  
Chan Hee Park ◽  
Cheol Sang Kim

Deer antler velvet (DAV), Cornu Cervi Pantotrichum, has been known for the outstanding growth rate and used in extracted liquid form in oriental herbal medicine for the tissue regeneration. The DAV is also famous for the abundance of many different minerals, proteins, growth factors and interleukins. The immense amount of DAV is consumed to produce DAV extract in Asian countries. However, the mechanical strength and the morphologic features of DAV have been overlooked. In this study, we revisited the possibility of DAV as a bone tissue scaffold. We first obtained DAV particles via physical decellularization followed by levigation procedure and then applied to the fabrication of three-dimensional porous alginate/DAVP sponge through lyophilizing alginate/DAVP hydrogel as a potential bone tissue scaffold source. The morphological and physicochemical properties of alginate/DAVP sponge were characterized using UTM, SEM, FE-SEM, and FT-IR. The alginate-based highly porous sponge demonstrated the interconnected porous structure with DAVP and improved mechanical properties. We expected both alginate/DAVP and DAVP are potential for tissue engineering application.


2006 ◽  
Vol 49 ◽  
pp. 142-147 ◽  
Author(s):  
H. Ivankovic ◽  
G. Gallego Ferrer ◽  
E. Tkalcec ◽  
M. Ivankovic

Scaffold of hydroxyapatite for further tissue-engineering application was produced by hydrothermal treatment of cuttlefish bone originated aragonite at 200°C. Aragonite (CaCO3) monoliths were completely transformed into hydroxyapatite after 48 hours of HT treatment. The substitution of CO3- groups predominantly into the PO4 3- sites of the Ca10(PO4)6(OH)2 structure was suggested by FTIR spectroscopy. SEM micrographs have shown that the interconnected hollow structure with pillars connecting parallel lamellae in cuttlefish bone is maintained after conversion. Specific surface area (SBET) and total pore volume increased and mean pore size decreased by HT treatment.


2021 ◽  
Vol 29 (3) ◽  
pp. 191-198
Author(s):  
Zahra Orafa ◽  
Shiva Irani ◽  
Ali Zamanian ◽  
Hadi Bakhshi ◽  
Habib Nikukar ◽  
...  

2020 ◽  
Vol 249 ◽  
pp. 123010 ◽  
Author(s):  
Senthil Rethinam ◽  
Bahri Basaran ◽  
Sumathi Vijayan ◽  
Ali Mert ◽  
Oğuz Bayraktar ◽  
...  

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0163902 ◽  
Author(s):  
Hee Jeong Yoon ◽  
Su Ryon Shin ◽  
Jae Min Cha ◽  
Soo-Hong Lee ◽  
Jin-Hoi Kim ◽  
...  

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