Automatic segmentation of Computed Tomography (CT) images of domestic pig skeleton using a 3D expansion of Dijkstra’s algorithm

2016 ◽  
Vol 121 ◽  
pp. 191-194 ◽  
Author(s):  
Lars Erik Gangsei ◽  
Jørgen Kongsro
2017 ◽  
Author(s):  
◽  
D. E. Rodríguez-Obregón

A method to estimate the pulmonary fibrosis in computed tomography (CT) imaging is presented. A semi-automatic segmentation algorithm based on the Chan-Vese method was used. The proposed method shows a similar fibrosis region with respect to clinical expert. However, the results need to be validated in a bigger data base. The proposed method approximates a fibrosis percentage that allows to achieve this procedure easily in order to support its implementation in the clinical practice minimizing the clinical expert subjectivity and generating a quantitativeestimation of fibrosis region.


2017 ◽  
Author(s):  
◽  
D. E. Rodríguez-Obregón

A method to estimate the pulmonary fibrosis in computed tomography (CT) imaging is presented. A semi-automatic segmentation algorithm based on the Chan-Vese method was used. The proposed method shows a similar fibrosis region with respect to clinical expert. However, the results need to be validated in a bigger data base. The proposed method approximates a fibrosis percentage that allows to achieve this procedure easily in order to support its implementation in the clinical practice minimizing the clinical expert subjectivity and generating a quantitativeestimation of fibrosis region.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jared Hamwood ◽  
Beat Schmutz ◽  
Michael J. Collins ◽  
Mark C. Allenby ◽  
David Alonso-Caneiro

AbstractThis paper proposes a fully automatic method to segment the inner boundary of the bony orbit in two different image modalities: magnetic resonance imaging (MRI) and computed tomography (CT). The method, based on a deep learning architecture, uses two fully convolutional neural networks in series followed by a graph-search method to generate a boundary for the orbit. When compared to human performance for segmentation of both CT and MRI data, the proposed method achieves high Dice coefficients on both orbit and background, with scores of 0.813 and 0.975 in CT images and 0.930 and 0.995 in MRI images, showing a high degree of agreement with a manual segmentation by a human expert. Given the volumetric characteristics of these imaging modalities and the complexity and time-consuming nature of the segmentation of the orbital region in the human skull, it is often impractical to manually segment these images. Thus, the proposed method provides a valid clinical and research tool that performs similarly to the human observer.


Author(s):  
Valeria Vendries ◽  
Tamas Ungi ◽  
Jordan Harry ◽  
Manuela Kunz ◽  
Jana Podlipská ◽  
...  

Abstract Purpose Osteophytes are common radiographic markers of osteoarthritis. However, they are not accurately depicted using conventional imaging, thus hampering surgical interventions that rely on pre-operative images. Studies have shown that ultrasound (US) is promising at detecting osteophytes and monitoring the progression of osteoarthritis. Furthermore, three-dimensional (3D) ultrasound reconstructions may offer a means to quantify osteophytes. The purpose of this study was to compare the accuracy of osteophyte depiction in the knee joint between 3D US and conventional computed tomography (CT). Methods Eleven human cadaveric knees were pre-screened for the presence of osteophytes. Three osteoarthritic knees were selected, and then, 3D US and CT images were obtained, segmented, and digitally reconstructed in 3D. After dissection, high-resolution structured light scanner (SLS) images of the joint surfaces were obtained. Surface matching and root mean square (RMS) error analyses of surface distances were performed to assess the accuracy of each modality in capturing osteophytes. The RMS errors were compared between 3D US, CT and SLS models. Results Average RMS error comparisons for 3D US versus SLS and CT versus SLS models were 0.87 mm ± 0.33 mm (average ± standard deviation) and 0.95 mm ± 0.32 mm, respectively. No statistical difference was found between 3D US and CT. Comparative observations of imaging modalities suggested that 3D US better depicted osteophytes with cartilage and fibrocartilage tissue characteristics compared to CT. Conclusion Using 3D US can improve the depiction of osteophytes with a cartilaginous portion compared to CT. It can also provide useful information about the presence and extent of osteophytes. Whilst algorithm improvements for automatic segmentation and registration of US are needed to provide a more robust investigation of osteophyte depiction accuracy, this investigation puts forward the potential application for 3D US in routine diagnostic evaluations and pre-operative planning of osteoarthritis.


Author(s):  
Qi Yang ◽  
Yunke Li ◽  
Mengyi Zhang ◽  
Tian Wang ◽  
Fei Yan ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Junyoung Park ◽  
Jae Sung Lee ◽  
Dongkyu Oh ◽  
Hyun Gee Ryoo ◽  
Jeong Hee Han ◽  
...  

AbstractQuantitative single-photon emission computed tomography/computed tomography (SPECT/CT) using Tc-99m pertechnetate aids in evaluating salivary gland function. However, gland segmentation and quantitation of gland uptake is challenging. We develop a salivary gland SPECT/CT with automated segmentation using a deep convolutional neural network (CNN). The protocol comprises SPECT/CT at 20 min, sialagogue stimulation, and SPECT at 40 min post-injection of Tc-99m pertechnetate (555 MBq). The 40-min SPECT was reconstructed using the 20-min CT after misregistration correction. Manual salivary gland segmentation for %injected dose (%ID) by human experts proved highly reproducible, but took 15 min per scan. An automatic salivary segmentation method was developed using a modified 3D U-Net for end-to-end learning from the human experts (n = 333). The automatic segmentation performed comparably with human experts in voxel-wise comparison (mean Dice similarity coefficient of 0.81 for parotid and 0.79 for submandibular, respectively) and gland %ID correlation (R2 = 0.93 parotid, R2 = 0.95 submandibular) with an operating time less than 1 min. The algorithm generated results that were comparable to the reference data. In conclusion, with the aid of a CNN, we developed a quantitative salivary gland SPECT/CT protocol feasible for clinical applications. The method saves analysis time and manual effort while reducing patients’ radiation exposure.


2021 ◽  
Vol 17 (4) ◽  
pp. 1-16
Author(s):  
Xiaowe Xu ◽  
Jiawei Zhang ◽  
Jinglan Liu ◽  
Yukun Ding ◽  
Tianchen Wang ◽  
...  

As one of the most commonly ordered imaging tests, the computed tomography (CT) scan comes with inevitable radiation exposure that increases cancer risk to patients. However, CT image quality is directly related to radiation dose, and thus it is desirable to obtain high-quality CT images with as little dose as possible. CT image denoising tries to obtain high-dose-like high-quality CT images (domain Y ) from low dose low-quality CT images (domain X ), which can be treated as an image-to-image translation task where the goal is to learn the transform between a source domain X (noisy images) and a target domain Y (clean images). Recently, the cycle-consistent adversarial denoising network (CCADN) has achieved state-of-the-art results by enforcing cycle-consistent loss without the need of paired training data, since the paired data is hard to collect due to patients’ interests and cardiac motion. However, out of concerns on patients’ privacy and data security, protocols typically require clinics to perform medical image processing tasks including CT image denoising locally (i.e., edge denoising). Therefore, the network models need to achieve high performance under various computation resource constraints including memory and performance. Our detailed analysis of CCADN raises a number of interesting questions that point to potential ways to further improve its performance using the same or even fewer computation resources. For example, if the noise is large leading to a significant difference between domain X and domain Y , can we bridge X and Y with a intermediate domain Z such that both the denoising process between X and Z and that between Z and Y are easier to learn? As such intermediate domains lead to multiple cycles, how do we best enforce cycle- consistency? Driven by these questions, we propose a multi-cycle-consistent adversarial network (MCCAN) that builds intermediate domains and enforces both local and global cycle-consistency for edge denoising of CT images. The global cycle-consistency couples all generators together to model the whole denoising process, whereas the local cycle-consistency imposes effective supervision on the process between adjacent domains. Experiments show that both local and global cycle-consistency are important for the success of MCCAN, which outperforms CCADN in terms of denoising quality with slightly less computation resource consumption.


2020 ◽  
Author(s):  
Fredrik Ljunggren ◽  
Kristian Persson ◽  
Anders Peterson ◽  
Christiane Schmidt

Abstract We present an algorithm to insert a train path in an existing railway timetable close to operation, when we want to affect the existing (passenger) traffic as little as possible. Thus, we consider all other trains as fixed, and aim for a resulting train path that maximizes the bottleneck robustness, that is, a train path that maximizes the temporal distance to neighboring trains in the timetable. Our algorithm is based on a graph formulation of the problem and uses a variant of Dijkstra’s algorithm. We present an extensive experimental evaluation of our algorithm for the Swedish railway stretch from Malmö to Hallsberg. Moreover, we analyze the size of our constructed graph.


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