Inverted colloidal crystal scaffolds with induced pluripotent stem cells for nerve tissue engineering

2013 ◽  
Vol 102 ◽  
pp. 789-794 ◽  
Author(s):  
Yung-Chih Kuo ◽  
Chun-Wei Chen
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Colloidal Crystal ◽  
Nerve Tissue ◽  
Nerve Tissue Engineering ◽  
Induced Pluripotent ◽  
Colloidal Crystal Scaffolds

scholarly journals Induced Pluripotent Stem Cells from Human Placental Chorion for Perinatal Tissue Engineering Applications

2014 ◽  
Vol 20 (9) ◽  
pp. 731-740 ◽  
Author(s):  
Guihua Jiang ◽  
Julie Di Bernardo ◽  
Cynthia J. DeLong ◽  
André Monteiro da Rocha ◽  
K. Sue O'Shea ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Engineering Applications ◽  
Induced Pluripotent

scholarly journals Tissue Engineering of Cartilage Using Collagen Scaffold Enriched with Plant Polysaccharides

Cartilage ◽  
2021 ◽  
pp. 194760352110078
Author(s):  
K. Uday Chandrika ◽  
Sapna Kacha ◽  
Anuja S. Nair ◽  
Vijayishwer S. Jamwal ◽  
Shruti Sandilya ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Gum Arabic ◽  
In Vitro Cytotoxicity ◽  
Health Care Economics ◽  
Self Healing ◽  
Induced Pluripotent

Degenerative diseases associated with articular cartilage pose a huge burden on health care economics. The nature of the tissue involved and the changes therein do not allow self-healing; and most of these problems are progressive. Tissue engineering offers some solutions provided we focus on the right kind of cells and the appropriate surrounding niches created for a particular tissue. The present study deals with the formation of polysaccharide rich stable scaffold of collagen after cross-linking with oxidized gum arabic. The scaffold was tested for its biocompatibility and ability to support cells. The in vitro cytotoxicity of the scaffolds toward induced pluripotent stem cells and chondrocytes was evaluated. Evaluation of expression of lineage specific markers indicates differentiation of induced pluripotent stem cells to chondrogenic lineage and maintenance of chondrocytes per se when grown in the scaffold. Animal studies were carried out to study the efficacy of the scaffold to repair the knee injuries. Cells along with the scaffold appeared to be the best filling, in repair of injured cartilage. These studies show that these scaffolds are potential candidates in applications such as tissue engineering of cartilage.

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