Sol-gel based antireflective coatings with superhydrophobicity and exceptionally low refractive indices built from trimethylsilanized hollow silica nanoparticles

2016 ◽  
Vol 509 ◽  
pp. 307-313 ◽  
Author(s):  
Chaoyou Tao ◽  
Hongwei Yan ◽  
Xiaodong Yuan ◽  
Qiang Yin ◽  
Jiayi Zhu ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Sol Gel ◽  
Refractive Indices ◽  
Antireflective Coatings ◽  
Hollow Silica ◽  
Hollow Silica Nanoparticles

scholarly journals Investigation of In Vitro Drug Release from Porous Hollow Silica Nanospheres Prepared of ZnS@SiO2Core-Shell

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Leila Vafayi ◽  
Soodabe Gharibe
Keyword(s):  
Electron Microscopy ◽  
Silica Nanoparticles ◽  
Sol Gel ◽  
In Vitro Release ◽  
Drug Carriers ◽  
Spherical Form ◽  
Zinc Blend ◽  
Hollow Silica ◽  
Hollow Silica Nanoparticles

In this contribution, porous hollow silica nanoparticles using inorganic nanosized ZnS as a template were prepared. The hydrothermal method was used to synthesize pure ZnS nanospheres material. The ZnS@SiO2core-shell nanocomposites were prepared using a simple sol-gel method successfully. The hollow silica nanostructures were achieved by selective removal of the ZnS core. The morphology, structure, and composition of the product were determined using powder X-ray diffraction (XRD), emission scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR). The results demonstrated clearly that the pure ZnS nanoparticles are in a spherical form with the average size of 40 nm and correspond with zinc blend structure. The porous hollow silica nanoparticles obtained were exploited as drug carriers to investigate in vitro release behavior of amoxicillin in simulated body fluid (SBF). UV-visible spectrometry was carried out to determine the amount of amoxicillin entrapped in the carrier. Amoxicillin release profile from porous hollow silica nanoparticles followed a three-stage pattern and indicated a delayed release effect.

Porous Hollow Silica Nanoparticles as Carriers for Controlled Delivery of Ibuprofen to Small Intestine

2006 ◽  
Vol 6 (9) ◽  
pp. 3139-3144 ◽  
Author(s):  
Li-Xiong Wen ◽  
Hao-Min Ding ◽  
Jie-Xin Wang ◽  
Jian-Feng Chen
Keyword(s):  
Small Intestine ◽  
Drug Release ◽  
Silica Nanoparticles ◽  
Sol Gel ◽  
Gastric Fluid ◽  
Sustained Drug Release ◽  
Hollow Silica ◽  
The Matrix ◽  
Hollow Silica Nanoparticles ◽  
Almost All

With two different methods, ibuprofen was entrapped into porous hollow silica nanoparticles (PHSNs) carriers, which were synthesized through a sol–gel route by using CaCO3 nanoparticles as the inorganic templates. By employing pressured CO2 as the loading medium, the amount of ibuprofen that was pressed into the carriers was ∼52% higher than that by simply soaking. The drug release behaviors of the ibuprofen-loaded PHSNs were investigated in a simulated intestine juice and an artificial gastric fluid, respectively, and it demonstrated a sustained release pattern in all cases and the sample prepared under high pressure had a lower release rate in both fluids and thus owned a greater sustained drug release capacity. In the acidic artificial gastric fluid, no silica was degraded and only 16% of the loaded ibuprofen was released from the matrix in 300 min. However, much more silica was degraded in the simulated intestine juice in a shorter time and almost all the loaded ibuprofen was dissolved into the solution eventually, resulting in a quicker and complete ibuprofen release. Therefore, the PHSNs can be utilized for applications of controlled drug delivery to small intestine.

Hollow Silica Nanoparticles Penetrate the Peripheral Nerve and Enhance the Nerve Blockade from Tetrodotoxin

Nano Letters ◽  
2017 ◽  
Vol 18 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Qian Liu ◽  
Claudia M. Santamaria ◽  
Tuo Wei ◽  
Chao Zhao ◽  
Tianjiao Ji ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Silica Nanoparticles ◽  
Hollow Silica ◽  
Nerve Blockade ◽  
Hollow Silica Nanoparticles
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