Rational design of hierarchical porous Fe3O4/rGO composites with lightweight and high-efficiency microwave absorption

2020 ◽  
Vol 22 ◽  
pp. 100492 ◽  
Author(s):  
Zhicheng Liu ◽  
Zhen Xiang ◽  
Baiwen Deng ◽  
Fei Pan ◽  
Juan Xiong ◽  
...  
Keyword(s):  
Microwave Absorption ◽  
Rational Design ◽  
High Efficiency ◽  
Hierarchical Porous

Rational design of core-shell Co@C nanotubes towards lightweight and high-efficiency microwave absorption

2020 ◽  
Vol 196 ◽  
pp. 108119 ◽  
Author(s):  
Huanqin Zhao ◽  
Yan Cheng ◽  
Zhu Zhang ◽  
Jiwen Yu ◽  
Jing Zheng ◽  
...  
Keyword(s):  
Microwave Absorption ◽  
Rational Design ◽  
High Efficiency ◽  
Core Shell ◽  
C Nanotubes

Hierarchical porous Ni@boehmite/nickel aluminum oxide flakes with enhanced microwave absorption ability

2017 ◽  
Vol 19 (13) ◽  
pp. 9128-9136 ◽  
Author(s):  
Biao Zhao ◽  
Junwei Liu ◽  
Xiaoqin Guo ◽  
Wanyu Zhao ◽  
Luyang Liang ◽  
...  
Keyword(s):  
Aluminum Oxide ◽  
Microwave Absorption ◽  
High Efficiency ◽  
Wide Band ◽  
Core Shell ◽  
Nickel Aluminum ◽  
Small Thickness ◽  
Hierarchical Porous

Hierarchical core–shell composites with porous cores and flaky shells show superior absorption which possess many features, such as lightweight, wide band, small thickness and high efficiency absorption.

Nucleoside Transporter-guided Cytarabine Conjugated Liposomes for Intracellular Methotrexate Delivery and Cooperative Choriocarcinoma Therapy

2021 ◽  
Author(s):  
Weidong Fei ◽  
Yunchun Zhao ◽  
Xiaodong Wu ◽  
Dongli Sun ◽  
Yao Yao ◽  
...  
Keyword(s):  
Targeted Delivery ◽  
Rational Design ◽  
High Efficiency ◽  
Nucleoside Transporter ◽  
Childbearing Age ◽  
Equilibrative Nucleoside Transporter ◽  
Choriocarcinoma Cells ◽  
Tumor Accumulation ◽  
Novel Strategy ◽  
Distribution Studies

Abstract The gestational trophoblastic tumor seriously endangers child productive needs and the health of women in childbearing age. Nanodrug-based therapy mediated by transporters provides novel strategy for the treatment of trophoblastic tumors. Focus on the overexpressed human equilibrative nucleoside transporter 1 (ENT1) on the membrane of choriocarcinoma cells (JEG-3), the cytarabine (Cy, a substrate of ENT1) grafted liposome (Cy-Lipo) was introduced for targeted delivery of methotrexate (Cy-Lipo@MTX) for choriocarcinoma therapy in this study. The ENT1 has high affinity for Cy-Lipo and can mediate the endocytosis of the designed nanovehicles into JEG-3 cells. The ENT1 protein maintains its transporting function through circulation and regeneration during endocytosis. Therefore, Cy-Lipo-based formulations achieved high tumor accumulation and retention in pharmacokinetic and distribution studies. More importantly, the designed Cy-lipid conjugation exhibited a synergistic therapeutic effect on choriocarcinoma. Finally, Cy-Lipo@MTX exerts an extremely powerful anti-choriocarcinoma effect with fewer side effects. This study suggests that the overexpressed ENT1 on choriocarcinoma cells holds a great potential to be a high-efficiency target for the rational design of active targeting nanotherapeutics.

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