scholarly journals Rapid diagnostic tests for infectious diseases in the emergency department

2020 ◽  
Author(s):  
D. Bouzid ◽  
M.-C. Zanella ◽  
S. Kerneis ◽  
B. Visseaux ◽  
L. May ◽  
...  
Keyword(s):  
Emergency Department ◽  
Infectious Diseases ◽  
Diagnostic Tests ◽  
Rapid Diagnostic Tests

scholarly journals Potential for community based surveillance of febrile diseases: Feasibility of self-administered rapid diagnostic tests in Iquitos, Peru and Phnom Penh, Cambodia

2021 ◽  
Vol 15 (4) ◽  
pp. e0009307
Author(s):  
Amy C. Morrison ◽  
Julia Schwarz ◽  
Jennie L. Mckenney ◽  
Jhonny Cordova ◽  
Jennifer E. Rios ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Disease Transmission ◽  
Diagnostic Tests ◽  
Large Scale ◽  
Health Workers ◽  
Rapid Diagnostic Tests ◽  
Community Members ◽  
Phnom Penh ◽  
Local Public Health ◽  
At Home

Rapid diagnostic tests (RDTs) have the potential to identify infectious diseases quickly, minimize disease transmission, and could complement and improve surveillance and control of infectious and vector-borne diseases during outbreaks. The U.S. Defense Threat Reduction Agency’s Joint Science and Technology Office (DTRA-JSTO) program set out to develop novel point-of-need RDTs for infectious diseases and deploy them for home use with no training. The aim of this formative study was to address two questions: 1) could community members in Iquitos, Peru and Phnom Penh, Cambodia competently use RDTs of different levels of complexity at home with visually based instructions provided, and 2) if an RDT were provided at no cost, would it be used at home if family members displayed febrile symptoms? Test kits with written and video (Peru only) instructions were provided to community members (Peru [n = 202]; Cambodia [n = 50]) or community health workers (Cambodia [n = 45]), and trained observers evaluated the competency level for each of the several steps required to successfully operate one of two multiplex RDTs on themselves or other consenting participant (i.e., family member). In Iquitos, >80% of residents were able to perform 11/12 steps and 7/15 steps for the two- and five-pathogen test, respectively. Competency in Phnom Penh never reached 80% for any of the 12 or 15 steps for either test; the percentage of participants able to perform a step ranged from 26–76% and 23–72%, for the two- and five-pathogen tests, respectively. Commercially available NS1 dengue rapid tests were distributed, at no cost, to households with confirmed exposure to dengue or Zika virus; of 14 febrile cases reported, six used the provided RDT. Our findings support the need for further implementation research on the appropriate level of instructions or training needed for diverse devices in different settings, as well as how to best integrate RDTs into existing local public health and disease surveillance programs at a large scale.

Posttravel Evaluation

2019 ◽  
pp. 603-652
Author(s):  
Gary W. Brunette ◽  
Jeffrey B. Nemhauser
Keyword(s):  
Antimicrobial Resistance ◽  
Infectious Diseases ◽  
Sexually Transmitted Infections ◽  
Diagnostic Tests ◽  
Rapid Diagnostic Tests ◽  
Sexually Transmitted

General Approach to the Returned Traveler Jessica K. Fairley Screening Asymptomatic Returned Travelers Michael Libman, Sapha Barkati Fever Mary Elizabeth Wilson Rapid Diagnostic Tests for Infectious Diseases Elizabeth Rabold, Jesse Waggoner Antimicrobial Resistance D. Cal Ham, Joseph Lutgring, Aditya Sharma Sexually Transmitted Infections Jodie Dionne-Odom...

scholarly journals Rapid Diagnostic Tests for Neglected Infectious Diseases: Case Study Highlights Need for Customer Awareness and Postmarket Surveillance

2016 ◽  
Vol 10 (11) ◽  
pp. e0004655 ◽  
Author(s):  
Barbara Barbé ◽  
Kristien Verdonck ◽  
Sayda El-Safi ◽  
Basudha Khanal ◽  
Syna Teav ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Diagnostic Tests ◽  
Rapid Diagnostic Tests

Peripheral Brain: Rapid Diagnostic Tests for Infectious Diseases Suitable for Office Use

2005 ◽  
Vol 26 (10) ◽  
pp. 383-387 ◽  
Author(s):  
Echezona Ezeanolue ◽  
Chinenye Ezeanolue ◽  
Barry Dashefsky
Keyword(s):  
Infectious Diseases ◽  
Diagnostic Tests ◽  
Rapid Diagnostic Tests

scholarly journals Diagnosis value of SARS-CoV-2 antigen/antibody combined testing using rapid diagnostic tests at hospital admission

2020 ◽  
Author(s):  
Nicolas Veyrenche ◽  
Karine Bollore ◽  
Amandine Pisoni ◽  
Anne-Sophie Bedin ◽  
Anne-Marie Mondain ◽  
...  
Keyword(s):  
Emergency Department ◽  
Hospital Admission ◽  
Diagnostic Tests ◽  
Rapid Diagnostic Tests ◽  
Rt Pcr ◽  
Cycle Threshold ◽  
Igm Elisa ◽  
Antigen Antibody ◽  
Negative Controls

Objectives: The implementation of rapid diagnostic tests (RDTs) may enhance the efficiency of SARS-CoV-2 testing, as RDTs are widely accessible and easy to use. The aim of this study was to evaluate the performance of a diagnosis strategy based on a combination of antigen and IgM/IgG serological RDTs. Methods: Plasma and nasopharyngeal samples were collected between 14 March and 11 April 2020 at hospital admission from 45 patients with RT-PCR confirmed COVID-19 and 20 negative controls. SARS-CoV-2 antigen (Ag) was assessed in nasopharyngeal swabs using the Coris Respi-Strip. For IgM/IgG detection, SureScreen Diagnostics and Szybio Biotech RDTs were used in addition to laboratory assays (Abbott Alinity i SARS-CoV-2 IgG and Theradiag COVID-19 IgM ELISA). Results: Using the Ag RDT, 13 out of 45 (29.0%) specimens tested positive, the sensitivity was 87.0% for Cycle Threshold (CT) values ≤ 25 and 0% for CT values > 25. IgG detection was associated with high CT values and the amount of time after the onset of symptoms. The profile of isolated IgM on RDTs was more frequently observed during the first and second week after the onset of symptoms. The combination of Ag and IgM/IgG RDTs enabled the detection of up to 84.0% of COVID-19 confirmed cases at hospital admission. Conclusion: Antigen and antibody-based RDTs showed suboptimal performances when used alone. However when used in combination, they are able to identify most COVID-19 patients admitted in an emergency department.

Peripheral Brain: Rapid Diagnostic Tests for Infectious Diseases Suitable for Office Use

2005 ◽  
Vol 26 (10) ◽  
pp. 383-387
Author(s):  
Echezona Ezeanolue ◽  
Chinenye Ezeanolue ◽  
Barry Dashefsky
Keyword(s):  
Infectious Diseases ◽  
Diagnostic Tests ◽  
Rapid Diagnostic Tests
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