Dual Arc Volumetric-modulated Arc Radiotherapy (VMAT) of Nasopharyngeal Carcinomas: A Simultaneous Integrated Boost Treatment Plan Comparison with Intensity-modulated Radiotherapies and Single Arc VMAT

2012 ◽  
Vol 24 (3) ◽  
pp. 196-207 ◽  
Author(s):  
T.-F. Lee ◽  
H.-M. Ting ◽  
P.-J. Chao ◽  
F.-M. Fang
Keyword(s):  
Treatment Plan ◽  
Simultaneous Integrated Boost ◽  
Plan Comparison ◽  
Intensity Modulated ◽  
Integrated Boost ◽  
Single Arc ◽  
Volumetric Modulated Arc Radiotherapy

PO-1087: Simultaneous integrated boost and volumetric modulated arc radiotherapy in rectal cancer

2020 ◽  
Vol 152 ◽  
pp. S575
Author(s):  
B. Low ◽  
J. Saunders ◽  
A. Othman ◽  
P. McLoone ◽  
N. Mohammed ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Simultaneous Integrated Boost ◽  
Integrated Boost ◽  
Volumetric Modulated Arc Radiotherapy

scholarly journals Single-Institute Clinical Experiences Using Whole-Field Simultaneous Integrated Boost (SIB) Intensity-Modulated Radiotherapy (IMRT) and Sequential IMRT in Postoperative Patients With Oral Cavity Cancer (OCC)

2020 ◽  
Vol 27 (1) ◽  
pp. 107327482090470
Author(s):  
Chen-Hsi Hsieh ◽  
Pei-Wei Shueng ◽  
Li-Ying Wang ◽  
Li-Jen Liao ◽  
Wu-Chia Lo ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Oral Cavity Cancer ◽  
Locally Advanced ◽  
Intensity Modulated Radiotherapy ◽  
Simultaneous Integrated Boost ◽  
Clinical Experiences ◽  
Risk Of Death ◽  
Intensity Modulated ◽  
Integrated Boost ◽  
Sequential Technique

This study aimed to review clinical experiences using whole-field simultaneous integrated boost (SIB) intensity-modulated radiotherapy (IMRT) and sequential IMRT in postoperative patients with oral cavity cancer (OCC). From November 2006 to December 2014, a total of 182 postoperative patients with OCC who underwent either SIB-IMRT (n = 63) or sequential IMRT (n = 119) were enrolled retrospectively and matched randomly according to multiple risk factors by a computer. The differences were well balanced after patient matching ( P = .38). The median follow-up time was 65 months. For patients treated with the SIB technique and the sequential technique, the respective mortality rates were 36.8% and 20.0% ( P = .04). The primary recurrence rates were 26.3% and 10.0% ( P = .02), respectively. The respective marginal failure rates were 26.7% and 16.7%. A multivariate logistic regression analysis showed that patients who received the SIB technique had a 2.74 times higher risk of death than those who received the sequential technique (95% confidence interval = 1.10-6.79, P = .03). Sequential IMRT provided a significantly lower dose to the esophagus (5.2 Gy, P = .02) and trachea (4.6 Gy, P = .03) than SIB-IMRT. For patients with locally advanced OCC, postoperative sequential IMRT may overcome an unpredictable geographic miss, potentially with a lower marginal failure rate in the primary area. Patients treated by sequential IMRT show equal overall survival benefits to those treated by SIB-IMRT and a lower mortality rate than those treated by SIB-IMRT. Additionally, a reduced dose to the esophagus and trachea compared to sequential IMRT was noted.

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