Determinants of new-onset diabetes in older adults–Results of a national cohort study

2015 ◽  
Vol 34 (5) ◽  
pp. 937-942 ◽  
Author(s):  
Alan C. Tsai ◽  
Shu-Hui Lee
Keyword(s):  
Older Adults ◽  
Cohort Study ◽  
Onset Diabetes ◽  
National Cohort ◽  
New Onset

scholarly journals The comparative risk of new-onset diabetes after prescription of drugs for cardiovascular risk prevention in primary care: a national cohort study

BMJ Open ◽  
2013 ◽  
Vol 3 (11) ◽  
pp. e003475 ◽  
Author(s):  
Olivia Currie ◽  
Dee Mangin ◽  
Jonathan Williman ◽  
Bianca McKinnon-Gee ◽  
Paul Bridgford
Keyword(s):  
Primary Care ◽  
Cohort Study ◽  
Cardiovascular Risk ◽  
Risk Prevention ◽  
Onset Diabetes ◽  
Comparative Risk ◽  
National Cohort ◽  
New Onset

scholarly journals Epidemiology and Mortality of New-Onset Diabetes After Dialysis: Taiwan national cohort study

Diabetes Care ◽  
2013 ◽  
Vol 36 (10) ◽  
pp. 3027-3032 ◽  
Author(s):  
K.-J. Tien ◽  
Z.-Z. Lin ◽  
C.-C. Chio ◽  
J.-J. Wang ◽  
C.-C. Chu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Onset Diabetes ◽  
National Cohort ◽  
New Onset

A multicenter prospective hospital-based cohort study on the efficacy and safety of pitavastatin.

2020 ◽  
Vol 17 ◽  
Author(s):  
Abdullah Shehab ◽  
Asim Ahmed Elnour ◽  
Akshaya Srikanth Bhagavathula ◽  
Joseph Pulavelil Kurian ◽  
Gazi Hassan ◽  
...  
Keyword(s):  
Cohort Study ◽  
Adverse Events ◽  
United Arab Emirates ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Efficacy And Safety ◽  
Onset Diabetes ◽  
The Mean ◽  
New Onset

Aims: We aim to investigate the efficacy and safety of pitavastatin 4 mg in a population of people living in the United Arab Emirates (UAE). Background: Pitavastatin is a member of the HMG-CoA reductase inhibitors family which was approved for use in adult subjects with primary hyperlipidemia or mixed dyslipidemia. To date, no published studies have assessed the efficacy and safety of pitavastatin in the United Arab Emirates. Objective: The main objective of the current study was to investigate the efficacy and safety of pitavastatin in subjects with dyslipidemia for primary prevention of cardiovascular diseases based on total cardiovascular risk. Methods: This was a multicentre (four private hospitals) prospective cohort study to analyze data on the use of pitavastatin for dyslipidemia in adult outpatients in Abu Dhabi and Dubai emirates, United Arab Emirates. We have followed-up the clinical profiles of subjects in four hospitals for six-weeks during the period from June 2015 to June 2017. Efficacy was based on the evaluation of the mean (± standard deviation) change in low-density lipoprotein cholesterol between baseline and week six after the initiation of pitavastatin therapy. Safety was reported as the incidence of adverse events occurred with the use of pitavastatin and the development of new-onset diabetes. Results: A total of 400 subjects who were receiving pitavastatin 4 mg were included. The mean age of subjects was 50.7 ±10.8 years, of these 79.0% were males. At the baseline, the mean level of total cholesterol was 185.4 ±41.5 mg/dL, low density lipoprotein was 154.9 ±48.55 mg/dL, high-density lipoprotein cholesterol was 40.5 ±11.23 mg/dL and fasting blood glucose was 115.0 (±16.63) mg/dl. At the end of six weeks, low density lipoprotein levels significantly decreased to 112.09 ±41.90 mg/dl (standard mean difference [SMD] (-42.8%), 95% CI: -42.88 [-49.17 to -36.58] mg/dl, P <0.001), while high density lipoprotein levels improved (SMD, 95% CI: 1.77% [0.25 to 3.28] mg/dl, P <0.022). There were 55 subjects (13.7%) reported various adverse events such as myalgia (7.5%), sleep disorders (2.5%), and myopathy (2.2%). Furthermore, 4 (1.0%) have had developed new-onset diabetes post six-weeks of initiation of pitavastatin therapy. Conclusion: Pitavastatin 4 mg had howed robust efficacy in reducing LDL-C levels and improving HDL-C levels in subjects with dyslipidemias. The use of pitavastatin was associated with a low discontinuation rate, fewer adverse events, and very limited cases of new-onset diabetes.

scholarly journals Psoriasis and New-Onset Diabetes: A Danish nationwide cohort study

Diabetes Care ◽  
2013 ◽  
Vol 36 (8) ◽  
pp. 2402-2407 ◽  
Author(s):  
U. Khalid ◽  
P. R. Hansen ◽  
G. H. Gislason ◽  
J. Lindhardsen ◽  
S. L. Kristensen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Onset Diabetes ◽  
New Onset
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