scholarly journals Health-Related Quality of Life of Patients With Multiple Myeloma Treated in Routine Clinical Practice in France

2019 ◽  
Vol 19 (1) ◽  
pp. e13-e28 ◽  
Author(s):  
Nicolas Despiégel ◽  
Chantal Touboul ◽  
Alain Flinois ◽  
Grèce Saba ◽  
Florence Suzan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Myeloma ◽  
Clinical Practice ◽  
Routine Clinical Practice ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

R-Scale for Pulmonary Fibrosis (PF): a simple, visual tool for the assessment of health-related quality of life

2021 ◽  
pp. 2100917
Author(s):  
Ciaran Scallan ◽  
Lauren Strand ◽  
Jennifer Hayes ◽  
Suha Kadura ◽  
Bridget Collins ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Practice ◽  
Pulmonary Fibrosis ◽  
Concurrent Validity ◽  
Rating Scale ◽  
Routine Clinical Practice ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

RationalePatients with Idiopathic Pulmonary Fibrosis (IPF) experience impaired health related quality of life (HRQoL). Several tools have been developed to objectively assess HRQoL in this patient population, but none are in use in routine clinical practice.ObjectivesTo develop a rapid, specific tool that can be used for patients with IPF during routine clinic visits.MethodsA novel and simple 5-item numerical rating scale (NRS) was developed and compared with two other previously validated tools. 100 consecutive patients with IPF managed at the center for ILD, were recruited to complete the R-Scale-PF, the Kings Brief Interstitial Lung Disease Questionnaire (K-BILD), and the EuroQol 5-Dimensional 5-Level Questionnaire (EQ-5D-5 L) in addition to pulmonary function and 6-min walk tests.Measurements and Main ResultsAll 100 patients successfully completed the three HRQoL tools with 53 completing them again at follow up visits. Internal consistency was high (Cronbach's α 0.825) with minimal floor/ceiling effect. Concurrent validity of the R-Scale-PF was moderate to high compared with the K-BILD (r=−0.713) and the EQ-5D-5 L (r=−0.665). Concurrent validity was moderate with physiologic measures (forced vital capacity, r=−0.307, 6-min walk distance, r=−0.383). The R-Scale-PF demonstrated good known-groups validity when comparing scores across stages of disease severity.ConclusionsThe R-Scale-PF correlates well with the K-BILD and EQ-5D-5 L. It is hoped that this novel simple NRS tool subject to validation in patients from other centers will provide the opportunity to objectively measure HRQoL in routine clinical practice for patients with IPF.

scholarly journals Health-Related Quality of Life Following Allogeneic Hematopoietic Stem Cell Transplantation

Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 248-254 ◽  
Author(s):  
Margaret Bevans
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Clinical Practice ◽  
Hematopoietic Stem Cell Transplantation ◽  
Health Related Quality ◽  
Hematopoietic Stem ◽  
Allogeneic Hsct ◽  
Related Quality ◽  
Health Related

Abstract It is common knowledge that an allogeneic hematopoietic stem cell transplantation (HSCT) will have an enormous impact on the lives of transplant recipients and their families. Once an appropriate donor is identified, the curative potential of this treatment often drives the decision to proceed knowing that there will be intense physiologic toxicities and adverse effects on health-related quality of life (HRQL). Twenty-five years ago, HRQL was identified as an efficacy parameter in the evaluation of new anticancer drug therapy. Overall, the evidence suggests that an allogeneic HSCT has a significant impact on the overall HRQL of recipients, which is a result of decrements across all dimensions, including a significant symptom profile. The degree of impact on overall HRQL and the multiple dimensions varies across the transplant trajectory. Specific HRQL dimensions, such as physical function and symptoms, are easily incorporated into a clinician's assessment whereas other dimensions (eg, psychosocial) are less commonly integrated. The translation of HRQL results to improve clinical practice is not well established. Clinicians are often uncertain when to assess the scope of HRQL and how to interpret the information in a clinically meaningful way. The purpose of this review is to highlight the quality-of-life effects of allogeneic HSCT and discuss application into clinical practice.

Measurement of health‐related quality of life in multiple myeloma

1996 ◽  
Vol 92 (3) ◽  
pp. 604-613 ◽  
Author(s):  
Finn Wisløff ◽  
Sverre Eika ◽  
Erik Hippe ◽  
Martin Hjorth ◽  
Erik Holmberg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Myeloma ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related
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