Bath Psoralen-ultraviolet A and Narrowband Ultraviolet B Phototherapy as Initial Therapy for Early-stage Mycosis Fungoides: A Retrospective Cohort of 267 Cases at the University of Toronto

2017 ◽  
Vol 17 (9) ◽  
pp. 604-612 ◽  
Author(s):  
Mohammad Almohideb ◽  
Sandra Walsh ◽  
Scott Walsh ◽  
Neil Shear ◽  
Raed Alhusayen
Keyword(s):  
Mycosis Fungoides ◽  
Retrospective Cohort ◽  
Early Stage ◽  
Initial Therapy ◽  
Ultraviolet B ◽  
Ultraviolet A ◽  
University Of Toronto ◽  
The University

scholarly journals Phototherapy as a treatment of early-stage mycosis fungoides and predictive factors for disease recurrence: A 17-year retrospective study

2021 ◽  
Vol 0 ◽  
pp. 1-7
Author(s):  
Ploysyne Rattanakaemakorn ◽  
Monthanat Ploydaeng ◽  
Siriorn Udompanich ◽  
Kunlawat Thadanipon ◽  
Suthinee Rutnin ◽  
...  
Keyword(s):  
Complete Remission ◽  
Effective Treatment ◽  
Median Time ◽  
Mycosis Fungoides ◽  
Predictive Factors ◽  
Early Stage ◽  
Treatment Options ◽  
Ultraviolet B ◽  
Disease Stage ◽  
Ultraviolet A

Background: Mycosis fungoides is the most common form of cutaneous T-cell lymphoma. Narrowband ultraviolet B and psoralen and ultraviolet A are effective treatment options, but studies of their treatment efficacy and disease relapse remain limited. Objectives: This study aimed (1) to determine the efficacy of narrowband ultraviolet B and psoralen and ultraviolet A as a treatment for early-stage mycosis fungoides and explore the predictive factors for complete remission and (2) to determine the relapse rate and analyze their predictive factors, including the utility of maintenance therapy. Methods: This was a retrospective cohort study consisting of 61 patients with early-stage mycosis fungoides (IA - IB) treated with narrowband ultraviolet B or psoralen and ultraviolet A as the first-line therapy from January 2002 to December 2018 at the Division of Dermatology, Ramathibodi Hospital, Bangkok, Thailand. Cox regression analysis and Kaplan–Meier survival curve were performed for the main outcomes. Results: A complete remission was achieved by 57 (93.5%) patients. The median time to remission was 7.80 ± 0.27 months. Types of phototherapy (narrowband ultraviolet B or psoralen and ultraviolet A), age and gender did not associate with time to remission, while the presence of poikiloderma and higher disease stage led to a longer time to remission. The cumulative incidence of relapse was 50.8%. The median time to relapse was 24.78 ± 5.48 months. In patients receiving phototherapy during the maintenance period, a treatment duration longer than six months was associated with a significantly longer relapse-free interval. Conclusion: Narrow-band-ultraviolet B and psoralen and ultraviolet A are effective treatment options for early-stage mycosis fungoides. Maintenance treatment by phototherapy for at least six months seems to prolong remission.

scholarly journals Narrowband Ultraviolet B Phototherapy of Early Stage Mycosis Fungoides in Korean Patients

2011 ◽  
Vol 23 (4) ◽  
pp. 474 ◽  
Author(s):  
Min Soo Jang ◽  
Jae Woo Baek ◽  
Jong Bin Park ◽  
Dong Young Kang ◽  
Jin Seuk Kang ◽  
...  
Keyword(s):  
Mycosis Fungoides ◽  
Early Stage ◽  
Ultraviolet B ◽  
Korean Patients

Efficacy of Low-Dose Ultraviolet A-1 Phototherapy for Parapsoriasis/Early-Stage Mycosis Fungoides

2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Kenan Aydogan ◽  
Serkan Yazici ◽  
Saduman Balaban Adim ◽  
Isil Tilki Gunay ◽  
Ferah Budak ◽  
...  
Keyword(s):  
Mycosis Fungoides ◽  
Low Dose ◽  
Early Stage ◽  
Ultraviolet A

A chart review of patients with early-stage mycosis fungoides treated with psoralen plus ultraviolet A

2009 ◽  
Vol 23 (2) ◽  
pp. 218-219
Author(s):  
C Antoniou ◽  
V Nikoloau ◽  
M Siakantaris ◽  
C Bamia ◽  
A Stratigos ◽  
...  
Keyword(s):  
Mycosis Fungoides ◽  
Chart Review ◽  
Early Stage ◽  
Ultraviolet A

Role of bath psoralen plus ultraviolet A in early-stage mycosis fungoides

2014 ◽  
Vol 71 (3) ◽  
pp. 536-541 ◽  
Author(s):  
Felix Pavlotsky ◽  
Emmilia Hodak ◽  
Dan Ben Amitay ◽  
Aviv Barzilai
Keyword(s):  
Mycosis Fungoides ◽  
Early Stage ◽  
Ultraviolet A

Ultraviolet-B Phototherapy Is Successful in Japanese Patients with Early-Stage Mycosis Fungoides

2003 ◽  
Vol 30 (11) ◽  
pp. 789-796 ◽  
Author(s):  
Masatoshi Abe ◽  
Kazunori Ohnishi ◽  
Chie Kan ◽  
Osamu Ishikawa
Keyword(s):  
Mycosis Fungoides ◽  
Early Stage ◽  
Japanese Patients ◽  
Ultraviolet B
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