scholarly journals Transcranial magnetic stimulation over dorsolateral prefrontal cortex in Parkinson’s disease

2007 ◽  
Vol 118 (1) ◽  
pp. 131-139 ◽  
Author(s):  
Miguel Fernández del Olmo ◽  
Olalla Bello ◽  
Javier Cudeiro
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Prefrontal Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Dorsolateral Prefrontal Cortex ◽  
Dorsolateral Prefrontal

scholarly journals Dorsolateral Prefrontal Cortex: A Possible Target for Modulating Dyskinesias in Parkinson's Disease by Repetitive Transcranial Magnetic Stimulation

2008 ◽  
Vol 2008 ◽  
pp. 1-6 ◽  
Author(s):  
I. Rektorova ◽  
S. Sedlackova ◽  
S. Telecka ◽  
A. Hlubocky ◽  
I. Rektor
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Prefrontal Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Motor Cortex ◽  
Magnetic Stimulation ◽  
Dorsolateral Prefrontal Cortex ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Controlled Study ◽  
Dorsolateral Prefrontal

We studied whether five sessions of 10 Hz repetitive transcranial magnetic stimulation (rTMS treatment) applied over the dorsolateral prefrontal cortex (DLPFC) or the primary motor cortex (MC) in advanced Parkinson's disease (PD) patients would have any effect on L-dopa-induced dyskinesias and cortical excitability. We aimed at a randomised, controlled study. Single-pulse transcranial magnetic stimulation (TMS), paired-pulse transcranial magnetic stimulation, and the Unified Parkinson's Disease Rating Scale (UPDRS parts III and IV) were performed prior to, immediately after, and one week after an appropriate rTMS treatment. Stimulation of the left DLPFC induced a significant motor cortex depression and a trend towards the improvement of L-dopa-induced dyskinesias.

scholarly journals Single-Pulse Transcranial Magnetic Stimulation-Evoked Potential Amplitudes and Latencies in the Motor and Dorsolateral Prefrontal Cortex among Young, Older Healthy Participants, and Schizophrenia Patients

2021 ◽  
Vol 11 (1) ◽  
pp. 54
Author(s):  
Yoshihiro Noda ◽  
Mera S. Barr ◽  
Reza Zomorrodi ◽  
Robin F. H. Cash ◽  
Pantelis Lioumis ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Dorsolateral Prefrontal Cortex ◽  
Evoked Potential ◽  
Single Pulse ◽  
Signal Propagation ◽  
Lower Amplitude ◽  
Dorsolateral Prefrontal ◽  
The Right

Background: The combination of transcranial magnetic stimulation (TMS) with electroencephalography (EEG) allows for non-invasive investigation of cortical response and connectivity in human cortex. This study aimed to examine the amplitudes and latencies of each TMS-evoked potential (TEP) component induced by single-pulse TMS (spTMS) to the left motor (M1) and dorsolateral prefrontal cortex (DLPFC) among healthy young participants (YNG), older participants (OLD), and patients with schizophrenia (SCZ). Methods: We compared the spatiotemporal characteristics of TEPs induced by spTMS among the groups. Results: Compared to YNG, M1-spTMS induced lower amplitudes of N45 and P180 in OLD and a lower amplitude of P180 in SCZ, whereas the DLPFC-spTMS induced a lower N45 in OLD. Further, OLD demonstrated latency delays in P60 after M1-spTMS and in N45-P60 over the right central region after left DLPFC-spTMS, whereas SCZ demonstrated latency delays in N45-P60 over the midline and right central regions after DLPFC-spTMS. Conclusions: These findings suggest that inhibitory and excitatory mechanisms mediating TEPs may be altered in OLD and SCZ. The amplitude and latency changes of TEPs with spTMS may reflect underlying neurophysiological changes in OLD and SCZ, respectively. The spTMS administered to M1 and the DLPFC can probe cortical functions by examining TEPs. Thus, TMS-EEG can be used to study changes in cortical connectivity and signal propagation from healthy to pathological brains.

Repetitive Transcranial Magnetic Stimulation Improves Depersonalization: A Case Report

CNS Spectrums ◽  
2004 ◽  
Vol 9 (5) ◽  
pp. 375-376 ◽  
Author(s):  
Alejandro M. Jiménez-Genchi
Keyword(s):  
Prefrontal Cortex ◽  
Case Report ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Dorsolateral Prefrontal Cortex ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Treatment Resistant ◽  
Depersonalization Disorder ◽  
Dorsolateral Prefrontal

AbstractDepersonalization disorder is a poorly understood and treatment-resistant condition. This report describes a patient with depersonalization disorder who underwent six sessions of repetitive transcranial magnetic stimulation on the left dorsolateral prefrontal cortex. Repetitive transcranial magnetic stimulation produced a 28% reduction on depersonalization scores.

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